2RI9

Penicillium citrinum alpha-1,2-mannosidase in complex with a substrate analog

Summary for 2RI9

• Entry DOI: 10.2210/pdb2ri9/pdb
• Related: 1kkt 1kre 1krf 2RI8
• Descriptor: Mannosyl-oligosaccharide alpha-1,2-mannosidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: alternative conformations, modulation of activity, glycoprotein, glycosidase, hydrolase, secreted
• Biological source: Penicillium citrinum
• Total number of polymer chains: 2
• Total formula weight: 110052.45

Authors

Lobsanov, Y.D.,Yoshida, T.,Desmet, T.,Nerinckx, W.,Yip, P.,Claeyssens, M.,Herscovics, A.,Howell, P.L. (deposition date: 2007-10-10, release date: 2008-03-25, Last modification date: 2020-07-29)

• Primary citation: Lobsanov, Y.D.,Yoshida, T.,Desmet, T.,Nerinckx, W.,Yip, P.,Claeyssens, M.,Herscovics, A.,Howell, P.L.; Modulation of activity by Arg407: structure of a fungal alpha-1,2-mannosidase in complex with a substrate analogue.; Acta Crystallogr.,Sect.D, 64:227-236, 2008; PubMed: 18323617; DOI: 10.1107/S0907444907065572

Experimental method

X-RAY DIFFRACTION (1.95 Å)