2RI9
Penicillium citrinum alpha-1,2-mannosidase in complex with a substrate analog
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004571 | molecular_function | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0006486 | biological_process | obsolete protein glycosylation |
| A | 0016020 | cellular_component | membrane |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0036503 | biological_process | ERAD pathway |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004571 | molecular_function | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005783 | cellular_component | endoplasmic reticulum |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0006486 | biological_process | obsolete protein glycosylation |
| B | 0016020 | cellular_component | membrane |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0036503 | biological_process | ERAD pathway |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"11714724","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P45700","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"11714724","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1KKT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KRE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1KRF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2RI8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2RI9","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1dl2 |
| Chain | Residue | Details |
| A | ASP1267 | |
| A | ARG1126 | |
| A | GLU1122 | |
| A | GLU1409 |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1dl2 |
| Chain | Residue | Details |
| B | GLU2409 | |
| B | ASP2267 | |
| B | GLU2122 | |
| B | ARG2126 |
