2GEV

Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with a coenzyme A derivative, Form-II (LT)

Summary for 2GEV

Related2ges 2get 2geu
DescriptorPantothenate kinase, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL (3R)-3-HYDROXY-4-{[3-({2-[(2-HYDROXYETHYL)DITHIO]ETHYL}AMINO)-3-OXOPROPYL]AMINO}-2,2-DIMETHYL-4-OXOBUTYL DIHYDROGEN DIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total)
Functional Keywordshomodimer, coa biosynthesis, nucleotide binding, transferase
Biological sourceMycobacterium tuberculosis
Total number of polymer chains1
Total molecular weight37299.32
Authors
Das, S.,Kumar, P.,Bhor, V.,Surolia, A.,Vijayan, M. (deposition date: 2006-03-20, release date: 2006-06-06, Last modification date: 2017-10-18)
Primary citation
Das, S.,Kumar, P.,Bhor, V.,Surolia, A.,Vijayan, M.
Invariance and variability in bacterial PanK: a study based on the crystal structure of Mycobacterium tuberculosis PanK.
Acta Crystallogr.,Sect.D, 62:628-638, 2006
PubMed: 16699190 (PDB entries with the same primary citation)
DOI: 10.1107/S0907444906012728
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.35 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.230152.0%7.3%10.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution