PDB: 30805 件ウェブページステータス検索Chemie searchBIRD

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6M31	Structural and Functional Insights into an Archaeal Lipid Synthase 分子名称: Digeranylgeranylglyceryl phosphate synthase, LAURYL DIMETHYLAMINE-N-OXIDE, MAGNESIUM ION, ... 著者 Ren, S, Cheng, W. 登録日 2020-03-02 公開日 2021-02-03 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural and Functional Insights into an Archaeal Lipid Synthase Cell Rep, 33, 2020
6TYQ	Salmonella Typhi PltB Homopentamer with Neu-5NAc-9OAc-alpha-2-6-Gal-beta-1-4-GlcNAc Glycans 分子名称: 9-O-acetyl-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Pertussis-like toxin subunit B 著者 Nguyen, T, Milano, S.K, Yang, Y.A, Song, J. 登録日 2019-08-09 公開日 2020-02-12 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 The role of 9-O-acetylated glycan receptor moieties in the typhoid toxin binding and intoxication. Plos Pathog., 16, 2020
6OHS	Structure of compound 3 (ML299) bound human Phospholipase D2 catalytic domain 分子名称: 4-bromo-N-{(2S)-1-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]propan-2-yl}benzamide, Phospholipase D2 著者 Metrick, C.M, Chodaparambil, J.V. 登録日 2019-04-06 公開日 2020-02-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Human PLD structures enable drug design and characterization of isoenzyme selectivity. Nat.Chem.Biol., 16, 2020
7NGT	Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound 分子名称: HTH-type transcriptional regulator EthR, SULFATE ION, ~{N}-butyl-4-methyl-piperidine-1-carboxamide 著者 Tomlinson, C.W.E, Tatum, N.J, Pohl, E. 登録日 2021-02-09 公開日 2022-02-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Systematic exploration of the hydrophobic capacity of the EthR binding site for lead compound optimization To Be Published
7NGN	Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound 分子名称: HTH-type transcriptional regulator EthR, SULFATE ION, ~{N}-cycloheptyl-4-methyl-piperidine-1-carboxamide 著者 Tomlinson, C.W.E, Tatum, N.J, Pohl, E. 登録日 2021-02-09 公開日 2022-02-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Systematic exploration of the hydrophobic capacity of the EthR binding site for lead compound optimization To Be Published
8CHX	Structure and function of LolA from Vibrio cholerae 分子名称: Outer-membrane lipoprotein carrier protein, ZINC ION 著者 Jaiman, D, Nagampalli, R, Persson, K. 登録日 2023-02-08 公開日 2023-06-21 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A comparative analysis of lipoprotein transport proteins: LolA and LolB from Vibrio cholerae and LolA from Porphyromonas gingivalis. Sci Rep, 13, 2023
6LX9	X-ray structure of human PPARalpha ligand binding domain-arachidonic acid co-crystals obtained by delipidation and cross-seeding 分子名称: ARACHIDONIC ACID, GLYCEROL, Peroxisome proliferator-activated receptor alpha 著者 Kamata, S, Saito, K, Honda, A, Ishikawa, R, Oyama, T, Ishii, I. 登録日 2020-02-10 公開日 2020-11-11 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 PPAR alpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates. Iscience, 23, 2020
7NGU	Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound 分子名称: HTH-type transcriptional regulator EthR, SULFATE ION, ~{N}-(4-methoxyphenyl)-4-methyl-piperidine-1-carboxamide 著者 Tomlinson, C.W.E, Tatum, N.J, Pohl, E. 登録日 2021-02-09 公開日 2022-02-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.26 Å) 主引用文献 Systematic exploration of the hydrophobic capacity of the EthR binding site for lead compound optimization To Be Published
6OC5	Lanthanide-dependent methanol dehydrogenase XoxF from Methylobacterium extorquens, in complex with Lanthanum 分子名称: LANTHANUM (III) ION, Lanthanide-dependent methanol dehydrogenase XoxF 著者 Fellner, M, Good, N.M, Martinez-Gomez, N.C, Hausinger, R.P, Hu, J. 登録日 2019-03-21 公開日 2020-05-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Lanthanide-dependent alcohol dehydrogenases require an essential aspartate residue for metal coordination and enzymatic function. J.Biol.Chem., 295, 2020
5AHK	Crystal structure of acetohydroxy acid synthase Pf5 from Pseudomonas protegens 分子名称: ACETOLACTATE SYNTHASE II, LARGE SUBUNIT, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Dobritzsch, D, Loschonsky, S, Mueller, M, Schneider, G. 登録日 2015-02-06 公開日 2016-03-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 The Crystal Structure of the Acetohydroxy Acid Synthase Pf5 from Pseudomonas Protegens To be Published
6M4Q	Cytochrome P450 monooxygenase StvP2 substrate-free structure 分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Sun, G, Hu, C, Mei, Q, Luo, M, Chen, X, Li, Z, Liu, Y, Deng, Z, Zhang, Z, Sun, Y. 登録日 2020-03-08 公開日 2020-08-12 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Uncovering the cytochrome P450-catalyzed methylenedioxy bridge formation in streptovaricins biosynthesis. Nat Commun, 11, 2020
8P4U	Alpha-1-antitrypsin - Sydney variant (G192C) 分子名称: Alpha-1-antitrypsin 著者 Kamuda, K, Lomas, D.A, Irving, J.A. 登録日 2023-05-23 公開日 2024-04-03 最終更新日 2024-07-17 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A novel pathological mutant reveals the role of torsional flexibility in the serpin breach in adoption of an aggregation-prone intermediate. Febs J., 291, 2024
6OIY	Structure of Escherichia coli bound to dGTP 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxyguanosinetriphosphate triphosphohydrolase, MANGANESE (II) ION 著者 Barnes, C.O, Wu, Y, Calero, G. 登録日 2019-04-09 公開日 2019-05-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.29 Å) 主引用文献 The crystal structure of dGTPase reveals the molecular basis of dGTP selectivity. Proc.Natl.Acad.Sci.USA, 116, 2019
6OCT	Crystal structure of human KCTD16 T1 domain 分子名称: BTB/POZ domain-containing protein KCTD16 著者 Zuo, H, Glaaser, I, Zhao, Y, Kurinov, I, Mosyak, L, Wang, H, Liu, J, Park, J, Frangaj, A, Sturchler, E, Zhou, M, McDonald, P, Geng, Y, Slesinger, P.A, Fan, Q.R. 登録日 2019-03-25 公開日 2019-04-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis for auxiliary subunit KCTD16 regulation of the GABABreceptor. Proc.Natl.Acad.Sci.USA, 116, 2019
8C16	Crystal structure of asymmetric ferredoxin/flavodoxin NADP+ oxidoreductase 2 (FNR2) H326V mutant from Bacillus cereus 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Ferredoxin--NADP reductase 著者 Rugtveit, A.K, Hammerstad, M, Hersleth, H.-P. 登録日 2022-12-20 公開日 2023-07-12 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 Functional Diversity of Homologous Oxidoreductases-Tuning of Substrate Specificity by a FAD-Stacking Residue for Iron Acquisition and Flavodoxin Reduction. Antioxidants, 12, 2023
8P6G	Crystal structure of the improved version of the Genetically Encoded Green Calcium Indicator YTnC2-5 分子名称: DI(HYDROXYETHYL)ETHER, Genetically Encoded Green Calcium Indicator YTnC2-5 based on Troponin C from toadfish 著者 Boyko, K.M, Nikolaeva, A.Y, Subach, O.M, Vlaskina, A.V, Agapova, Y.K, Popov, V.O, Subach, F.V. 登録日 2023-05-26 公開日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 YTnC2, an improved genetically encoded green calcium indicator based on toadfish troponin C. Febs Open Bio, 13, 2023
7NFJ	A heptameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-L28Y. 分子名称: CC-Type2-(LaId)4-L28Y 著者 Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. 登録日 2021-02-07 公開日 2022-03-02 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.19 Å) 主引用文献 Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
6AI2	Structure of the 328-692 fragment of FlhA (F459A) 分子名称: Flagellar biosynthesis protein FlhA 著者 Ogawa, Y, Kinoshita, M, Minamino, T, Imada, K. 登録日 2018-08-21 公開日 2019-03-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structural Insights into the Substrate Specificity Switch Mechanism of the Type III Protein Export Apparatus. Structure, 27, 2019
5AF4	Structure of Lys33-linked diUb 分子名称: GLYCEROL, SULFATE ION, UBIQUITIN 著者 Michel, M.A, Elliott, P.R, Swatek, K.N, Simicek, M, Pruneda, J.N, Wagstaff, J.L, Freund, S.M.V, Komander, D. 登録日 2015-01-19 公開日 2015-03-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Assembly and Specific Recognition of K29- and K33-Linked Polyubiquitin. Mol.Cell, 58, 2015
7NGG	Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound 分子名称: HTH-type transcriptional regulator EthR, ~{N}-(4-chlorophenyl)-4-methyl-piperidine-1-carboxamide 著者 Tomlinson, C.W.E, Tatum, N.J, Pohl, E. 登録日 2021-02-09 公開日 2022-02-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.17 Å) 主引用文献 Systematic exploration of the hydrophobic capacity of the EthR binding site for lead compound optimization To Be Published
8CR4	Crystal structure of recombinant LasBArtif from Pseudomonas aeruginosa AZPAE14816 分子名称: CALCIUM ION, Pro-elastase, ZINC ION 著者 Kolling, D, Koehnke, J. 登録日 2023-03-07 公開日 2023-07-05 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (0.91 Å) 主引用文献 Facile Production of the Pseudomonas aeruginosa Virulence Factor LasB in Escherichia coli for Structure-Based Drug Design. Chembiochem, 24, 2023
7NGM	Mycobacterium tuberculosis transcriptional regulator EthR with bound inhibitory compound 分子名称: 4-methyl-~{N}-[(1~{R})-1-phenylethyl]piperidine-1-carboxamide, HTH-type transcriptional regulator EthR 著者 Tomlinson, C.W.E, Tatum, N.J, Pohl, E. 登録日 2021-02-09 公開日 2022-02-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Systematic exploration of the hydrophobic capacity of the EthR binding site for lead compound optimization To Be Published
8P6I	Crystal structure of the 139H2 Fab fragment bound to Muc1 peptide epitope 分子名称: 139H2 HC, 139H2 LC, Mucin-1 著者 Beugelink, J.W, Peng, W, Siborova, M, Pronker, M.F, Snijder, J, Janssen, B.J.C. 登録日 2023-05-26 公開日 2024-04-03 最終更新日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Reverse-engineering the anti-MUC1 antibody 139H2 by mass spectrometry-based de novo sequencing. Life Sci Alliance, 7, 2024
6TZG	ADC-7 in complex with boronic acid transition state inhibitor S17083 分子名称: Beta-lactamase, [4-(3-aminocarbonylphenyl)-1,2,3-triazol-1-yl]methyl-phosphonooxy-borinic acid 著者 Fish, E.R, Powers, R.A, Wallar, B.J. 登録日 2019-08-12 公開日 2020-06-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.816 Å) 主引用文献 1,2,3-Triazolylmethaneboronate: A Structure Activity Relationship Study of a Class of beta-Lactamase Inhibitors againstAcinetobacter baumanniiCephalosporinase. Acs Infect Dis., 6, 2020
7SHB	Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI79 分子名称: 3C-like proteinase nsp5, benzyl [(2S)-1-({(2S)-1-[2-(3-amino-3-oxopropyl)-2-propanoylhydrazinyl]-4-methyl-1-oxopentan-2-yl}amino)-3-methyl-1-oxobutan-2-yl]carbamate (non-preferred name) 著者 Yang, K.S, Liu, W.R. 登録日 2021-10-08 公開日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure of the SARS-CoV-2 main protease in complex with inhibitors To Be Published

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