8P6I

Crystal structure of the 139H2 Fab fragment bound to Muc1 peptide epitope

Summary for 8P6I

Entry DOI	10.2210/pdb8p6i/pdb
Descriptor	Mucin-1, 139H2 HC, 139H2 LC, ... (4 entities in total)
Functional Keywords	fab fragment, peptide complex, immune system
Biological source	Homo sapiens More
Total number of polymer chains	6
Total formula weight	101628.80
Authors	Beugelink, J.W.,Peng, W.,Siborova, M.,Pronker, M.F.,Snijder, J.,Janssen, B.J.C. (deposition date: 2023-05-26, release date: 2024-04-03, Last modification date: 2024-04-10)
Primary citation	Peng, W.,Giesbers, K.C.,Siborova, M.,Beugelink, J.W.,Pronker, M.F.,Schulte, D.,Hilkens, J.,Janssen, B.J.,Strijbis, K.,Snijder, J. Reverse-engineering the anti-MUC1 antibody 139H2 by mass spectrometry-based de novo sequencing. Life Sci Alliance, 7:-, 2024 Cited by PubMed: 38508723 DOI: 10.26508/lsa.202302366 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation