7SHB

Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI79

Summary for 7SHB

• Entry DOI: 10.2210/pdb7shb/pdb
• Descriptor: 3C-like proteinase nsp5, benzyl [(2S)-1-({(2S)-1-[2-(3-amino-3-oxopropyl)-2-propanoylhydrazinyl]-4-methyl-1-oxopentan-2-yl}amino)-3-methyl-1-oxobutan-2-yl]carbamate (non-preferred name) (3 entities in total)
• Functional Keywords: main protease, viral protein, hydrolase-inhibitor complex, hydrolase/inhibitor
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 1
• Total formula weight: 34379.15

Authors

Yang, K.S.,Liu, W.R. (deposition date: 2021-10-08, release date: 2024-07-10)

• Primary citation: Yang, K.S.,Sankaran, B.,Liu, W.R.; Structure of the SARS-CoV-2 main protease in complex with inhibitors; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.85 Å)