8R9R
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5K5B
| Wild-type PAS-GAF fragment from Deinococcus radiodurans BphP | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, ACETATE ION, ... | 著者 | Takala, H, Edlund, P, Claesson, E, Ihalainen, J.A, Westenhoff, S. | 登録日 | 2016-05-23 | 公開日 | 2016-10-26 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | The room temperature crystal structure of a bacterial phytochrome determined by serial femtosecond crystallography. Sci Rep, 6, 2016
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5O6J
| Human NMT1 in complex with myristoyl-CoA and inhibitor IMP-1031 | 分子名称: | 1-[5-[3-fluoranyl-2-[2-(1,3,5-trimethylpyrazol-4-yl)ethoxy]phenyl]-1-methyl-indazol-3-yl]-~{N},~{N}-dimethyl-methanamine, Glycylpeptide N-tetradecanoyltransferase 1, MAGNESIUM ION, ... | 著者 | Brannigan, J.A, Wilkinson, A.J. | 登録日 | 2017-06-06 | 公開日 | 2018-05-16 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus. Nat Chem, 10, 2018
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5O6H
| Human NMT1 in complex with myristoyl-CoA and inhibitor IMP-917 | 分子名称: | 1-[5-[4-fluoranyl-2-[2-(1,3,5-trimethylpyrazol-4-yl)ethoxy]phenyl]-2~{H}-indazol-3-yl]-~{N},~{N}-dimethyl-methanamine, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Brannigan, J.A, Wilkinson, A.J. | 登録日 | 2017-06-06 | 公開日 | 2018-05-16 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | 主引用文献 | Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus. Nat Chem, 10, 2018
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5O48
| P.vivax NMT with an aminomethylindazole inhibitor bound | 分子名称: | 1-[5-(4-fluoranyl-2-methyl-phenyl)-1~{H}-indazol-3-yl]-~{N},~{N}-dimethyl-methanamine, 2-oxopentadecyl-CoA, CHLORIDE ION, ... | 著者 | Brannigan, J.A, Wilkinson, A.J. | 登録日 | 2017-05-26 | 公開日 | 2018-05-16 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus. Nat Chem, 10, 2018
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4E04
| RpBphP2 chromophore-binding domain crystallized by homologue-directed mutagenesis. | 分子名称: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, Bacteriophytochrome (Light-regulated signal transduction histidine kinase), PhyB1 | 著者 | Bellini, D, Papiz, M.Z. | 登録日 | 2012-03-02 | 公開日 | 2012-07-25 | 最終更新日 | 2013-01-23 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Dimerization properties of the RpBphP2 chromophore-binding domain crystallized by homologue-directed mutagenesis. Acta Crystallogr.,Sect.D, 68, 2012
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2YAL
| SinR, Master Regulator of biofilm formation in Bacillus subtilis | 分子名称: | HTH-TYPE TRANSCRIPTIONAL REGULATOR SINR, NICKEL (II) ION | 著者 | Colledge, V.L, Fogg, M.J, Levdikov, V.M, Leech, A, Dodson, E.J, Wilkinson, A.J. | 登録日 | 2011-02-23 | 公開日 | 2011-06-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Structure and Organisation of Sinr, the Master Regulator of Biofilm Formation in Bacillus Subtilis. J.Mol.Biol., 411, 2011
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6YCF
| Structure the bromelain protease from Ananas comosus in complex with the E64 inhibitor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, FBSB, ... | 著者 | Azarkan, M, Charlier, P, Herman, R, Delbrassine, F, Sauvage, E, M Rabet, N, Calvo Esposito, R, Kerff, F. | 登録日 | 2020-03-18 | 公開日 | 2020-11-25 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structures of the free and inhibitors-bound forms of bromelain and ananain from Ananas comosus stem and in vitro study of their cytotoxicity. Sci Rep, 10, 2020
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6YCE
| Structure the bromelain protease from Ananas comosus with a thiomethylated active cysteine | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FBSB, ISOPROPYL ALCOHOL, ... | 著者 | Azarkan, M, Charlier, P, Herman, R, Delbrassine, F, Sauvage, E, M Rabet, N, Calvo Esposito, R, Kerff, F. | 登録日 | 2020-03-18 | 公開日 | 2020-11-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structures of the free and inhibitors-bound forms of bromelain and ananain from Ananas comosus stem and in vitro study of their cytotoxicity. Sci Rep, 10, 2020
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6WPA
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6WP9
| AvaR1 bound to Avenolide | 分子名称: | (5S)-5-[(6R)-6-hydroxy-6-methyl-5-oxooctyl]furan-2(5H)-one, AvaR1 | 著者 | Kapoor, I, Olivares, P.J, Nair, S.K. | 登録日 | 2020-04-26 | 公開日 | 2020-07-22 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Biochemical basis for the regulation of biosynthesis of antiparasitics by bacterial hormones. Elife, 9, 2020
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4MDZ
| Crystal structure of a HD-GYP domain (a cyclic-di-GMP phosphodiesterase) containing a tri-nuclear metal centre | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), FE (III) ION, Metal dependent phosphohydrolase, ... | 著者 | Bellini, D, Walsh, M.A, Oxford Protein Production Facility (OPPF) | 登録日 | 2013-08-23 | 公開日 | 2014-02-19 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | Crystal structure of an HD-GYP domain cyclic-di-GMP phosphodiesterase reveals an enzyme with a novel trinuclear catalytic iron centre. Mol.Microbiol., 91, 2014
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3UM7
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7VW9
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6R8H
| Triosephosphate isomerase from liver fluke (Fasciola hepatica). | 分子名称: | SULFATE ION, Triosephosphate isomerase | 著者 | Ferraro, F, Corvo, I, Bergalli, L, Ilarraz, A, Cabrera, M, Gil, J, Susuki, B, Caffrey, C, Timson, D.J, Robert, X, Guillon, C, Alvarez, G. | 登録日 | 2019-04-01 | 公開日 | 2020-02-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Novel and selective inactivators of Triosephosphate isomerase with anti-trematode activity. Sci Rep, 10, 2020
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6U0S
| Crystal structure of the flavin-dependent monooxygenase PieE in complex with FAD and substrate | 分子名称: | 2,4-dichlorophenol 6-monooxygenase, 2-[(2E,5E,7E,9R,10R,11E)-10-hydroxy-3,7,9,11-tetramethyltrideca-2,5,7,11-tetraen-1-yl]-6-methoxy-3-methylpyridin-4-ol, CHLORIDE ION, ... | 著者 | Shi, R, Manenda, M. | 登録日 | 2019-08-14 | 公開日 | 2020-03-11 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | Structural analyses of the Group A flavin-dependent monooxygenase PieE reveal a sliding FAD cofactor conformation bridging OUT and IN conformations. J.Biol.Chem., 295, 2020
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2YD6
| Crystal structure of the N-terminal Ig1-2 module of Human Receptor Protein Tyrosine Phosphatase Delta | 分子名称: | CHLORIDE ION, CITRATE ANION, PTPRD PROTEIN | 著者 | Coles, C.H, Shen, Y, Tenney, A.P, Siebold, C, Sutton, G.C, Lu, W, Gallagher, J.T, Jones, E.Y, Flanagan, J.G, Aricescu, A.R. | 登録日 | 2011-03-17 | 公開日 | 2011-04-13 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Proteoglycan-Specific Molecular Switch for Rptp Sigma Clustering and Neuronal Extension. Science, 332, 2011
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5ZVJ
| Crystal structure of HtrA1 from Mycobacterium tuberculosis | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Serine protease | 著者 | Khundrakpam, H.S, Yadav, S, Kumar, D, Biswal, B.K. | 登録日 | 2018-05-10 | 公開日 | 2018-09-05 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The crystal structure of an essential high-temperature requirement protein HtrA1 (Rv1223) from Mycobacterium tuberculosis reveals its unique features. Acta Crystallogr D Struct Biol, 74, 2018
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6D8Z
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8R7Y
| Deoxyribonucleoside regulator DeoR in complex with the DNA operator | 分子名称: | Deoxyribonucleoside regulator, OL18 DNA operator, strand 1, ... | 著者 | Pachl, P, Soltysova, M, Rezacova, P. | 登録日 | 2023-11-27 | 公開日 | 2024-06-19 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Structural characterization of two prototypical repressors of SorC family reveals tetrameric assemblies on DNA and mechanism of function. Nucleic Acids Res., 52, 2024
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5ZHV
| Crystal structure of the PadR-family transcriptional regulator Rv3488 of Mycobacterium tuberculosis H37Rv in complex with zinc ion | 分子名称: | Transcriptional regulator, ZINC ION | 著者 | Meera, K, Pal, R.K, Arora, A, Biswal, B.K. | 登録日 | 2018-03-13 | 公開日 | 2018-10-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural and functional characterization of the transcriptional regulator Rv3488 ofMycobacterium tuberculosisH37Rv. Biochem. J., 475, 2018
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8EMQ
| Mouse apoferritin heavy chain with zinc determined using single-particle cryo-EM with Apollo camera. | 分子名称: | FE (III) ION, Ferritin heavy chain, N-terminally processed, ... | 著者 | Peng, R, Fu, X, Mendez, J.H, Randolph, P.H, Bammes, B, Stagg, S.M. | 登録日 | 2022-09-28 | 公開日 | 2022-12-21 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (1.66 Å) | 主引用文献 | Characterizing the resolution and throughput of the Apollo direct electron detector. J Struct Biol X, 7, 2023
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8EN7
| Mouse apoferritin heavy chain without zinc determined using single-particle cryo-EM with Apollo camera. | 分子名称: | FE (III) ION, Ferritin heavy chain, N-terminally processed | 著者 | Peng, R, Fu, X, Mendez, J.H, Randolph, P.H, Bammes, B, Stagg, S.M. | 登録日 | 2022-09-28 | 公開日 | 2022-12-21 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (1.68 Å) | 主引用文献 | Characterizing the resolution and throughput of the Apollo direct electron detector. J Struct Biol X, 7, 2023
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4U85
| Human Pin1 with cysteine sulfinic acid 113 | 分子名称: | POLYETHYLENE GLYCOL (N=34), Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 著者 | Li, W, Zhang, Y. | 登録日 | 2014-08-01 | 公開日 | 2015-04-08 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease. Neurobiol.Dis., 76, 2015
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4U84
| Human Pin1 with S-hydroxyl-cysteine 113 | 分子名称: | POLYETHYLENE GLYCOL (N=34), Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 著者 | Li, W, Zhang, Y. | 登録日 | 2014-08-01 | 公開日 | 2015-04-08 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease. Neurobiol.Dis., 76, 2015
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