6YCE

Structure the bromelain protease from Ananas comosus with a thiomethylated active cysteine

Summary for 6YCE

Entry DOI	10.2210/pdb6yce/pdb
Related	6Y6L 6YCB 6YCC 6YCD 6YCF 6YCG
Descriptor	FBSB, alpha-D-xylopyranose-(1-2)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	cysteine protease, stem bromelain protein, hydrolase
Biological source	Ananas comosus (Pineapple)
Total number of polymer chains	2
Total formula weight	47872.97
Authors	Azarkan, M.,Charlier, P.,Herman, R.,Delbrassine, F.,Sauvage, E.,M Rabet, N.,Calvo Esposito, R.,Kerff, F. (deposition date: 2020-03-18, release date: 2020-11-25, Last modification date: 2024-01-24)
Primary citation	Azarkan, M.,Maquoi, E.,Delbrassine, F.,Herman, R.,M'Rabet, N.,Calvo Esposito, R.,Charlier, P.,Kerff, F. Structures of the free and inhibitors-bound forms of bromelain and ananain from Ananas comosus stem and in vitro study of their cytotoxicity. Sci Rep, 10:19570-19570, 2020 Cited by PubMed: 33177555 DOI: 10.1038/s41598-020-76172-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation