5O6H
Human NMT1 in complex with myristoyl-CoA and inhibitor IMP-917
Summary for 5O6H
| Entry DOI | 10.2210/pdb5o6h/pdb |
| Related | 5MU6 5O6J |
| Descriptor | Glycylpeptide N-tetradecanoyltransferase 1, TETRADECANOYL-COA, PHOSPHATE ION, ... (8 entities in total) |
| Functional Keywords | myristoyl, transferase, inhibitor |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 94868.29 |
| Authors | Brannigan, J.A.,Wilkinson, A.J. (deposition date: 2017-06-06, release date: 2018-05-16, Last modification date: 2024-01-17) |
| Primary citation | Mousnier, A.,Bell, A.S.,Swieboda, D.P.,Morales-Sanfrutos, J.,Perez-Dorado, I.,Brannigan, J.A.,Newman, J.,Ritzefeld, M.,Hutton, J.A.,Guedan, A.,Asfor, A.S.,Robinson, S.W.,Hopkins-Navratilova, I.,Wilkinson, A.J.,Johnston, S.L.,Leatherbarrow, R.J.,Tuthill, T.J.,Solari, R.,Tate, E.W. Fragment-derived inhibitors of human N-myristoyltransferase block capsid assembly and replication of the common cold virus. Nat Chem, 10:599-606, 2018 Cited by PubMed: 29760414DOI: 10.1038/s41557-018-0039-2 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.29 Å) |
Structure validation
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