5O6H
Human NMT1 in complex with myristoyl-CoA and inhibitor IMP-917
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Glycylpeptide N-tetradecanoyltransferase 1 | polymer | 391 | 45453.3 | 2 | UniProt (P30419) Pfam (PF01233) Pfam (PF02799) In PDB | Homo sapiens (Human) | Myristoyl-CoA:protein N-myristoyltransferase 1,Type I N-myristoyltransferase,Peptide N-myristoyltransferase 1 |
2 | A, B | TETRADECANOYL-COA | non-polymer | 977.9 | 2 | Chemie (MYA) | |||
3 | A, B | PHOSPHATE ION | non-polymer | 95.0 | 8 | Chemie (PO4) | |||
4 | A, B | 1-[5-[4-fluoranyl-2-[2-(1,3,5-trimethylpyrazol-4-yl)ethoxy]phenyl]-2~{H}-indazol-3-yl]-~{N},~{N}-dimethyl-methanamine | non-polymer | 421.5 | 2 | Chemie (9M2) | |||
5 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
6 | A, B | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
7 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
8 | water | water | 18.0 | 1018 | Chemie (HOH) |
Sequence modifications
A, B: 109 - 496 (UniProt: P30419)
PDB | External Database | Details |
---|---|---|
Gly 106 | - | expression tag |
Pro 107 | - | expression tag |
His 108 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 90906.7 | |
Non-Polymers* | Number of molecules | 18 |
Total formula weight | 3961.6 | |
All* | Total formula weight | 94868.3 |