PDB: 66507 件ウェブページステータス検索Chemie searchBIRD

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6AV8	Exploring Cystine Dense Peptide Space to Open a Unique Molecular Toolbox 分子名称: U5-theraphotoxin-Hs1b 1 著者 Gewe, M.M, Rupert, P, Strong, R.K. 登録日 2017-09-01 公開日 2018-02-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Screening, large-scale production and structure-based classification of cystine-dense peptides. Nat. Struct. Mol. Biol., 25, 2018
5DRQ	Crystal structure of the Pseudomonas aeruginosa LpxC/LPC-040 complex 分子名称: N-[(2S)-3-amino-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl]-4-[4-(4-aminophenyl)buta-1,3-diyn-1-yl]benzamide, NITRATE ION, UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase, ... 著者 Lee, C.-J, Najeeb, J, Zhou, P. 登録日 2015-09-16 公開日 2016-03-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Drug design from the cryptic inhibitor envelope. Nat Commun, 7, 2016
5CYV	Crystal structure of CouR from Rhodococcus jostii RHA1 bound to p-coumaroyl-CoA 分子名称: ACETATE ION, CHLORIDE ION, MAGNESIUM ION, ... 著者 Stogios, P.J, Xu, X, Dong, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2015-07-30 公開日 2015-08-12 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 The activity of CouR, a MarR family transcriptional regulator, is modulated through a novel molecular mechanism. Nucleic Acids Res., 44, 2016
6B28	Crystal structure of human STAC2 Tandem SH3 Domains Q347I (296-411) 分子名称: SH3 and cysteine-rich domain-containing protein 2 著者 Wong King Yuen, S.M, Tung, C.C, Van Petegem, F. 登録日 2017-09-19 公開日 2017-10-25 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural insights into binding of STAC proteins to voltage-gated calcium channels. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5DV5	The fatty acid-responsive FadR repressor of Vibrio alginolyticus complex with Palmitoyl-CoA 分子名称: GntR family transcriptional regulator, Palmitoyl-CoA 著者 Lin, Y, Li, D.F, Feng, Y.J. 登録日 2015-09-21 公開日 2016-10-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Snapshort of Vibrio FadR-ligand complex structure reveals a new mechanism for bacterial fatty acid sensing To Be Published
6AOY	F9 pilus adhesin FmlH lectin domain from E. coli UTI89 co-crystallized with o-nitrophenyl beta-galactoside (ONPG) 分子名称: 2-nitrophenyl beta-D-galactopyranoside, Fml fimbrial adhesin FmlD, SULFATE ION 著者 Kalas, V, Hultgren, S.J. 登録日 2017-08-16 公開日 2018-02-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection. Proc.Natl.Acad.Sci.USA, 115, 2018
6B5Z	IMPase (AF2372) with 25 mM Asp 分子名称: 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, ASPARTIC ACID, Fructose-1,6-bisphosphatase/inositol-1-monophosphatase, ... 著者 Goldstein, R.I, Roberts, M. 登録日 2017-10-01 公開日 2018-10-03 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Osmolyte binding capacity of a dual action IMPase/FBPase (AF2372) To Be Published
2H9L	WDR5delta23 分子名称: SULFATE ION, WD-repeat protein 5 著者 Min, J.R, Schuetz, A, Allali-Hassani, A, Martin, F, Loppnau, P, Vedadi, M, Weigelt, J, Sundstrom, M, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC) 登録日 2006-06-10 公開日 2006-08-01 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural basis for molecular recognition and presentation of histone H3 By WDR5. Embo J., 25, 2006
6BA7	Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 2-Cl-4-OH-phenyldiketoacid 分子名称: (2Z)-4-(2-chloro-4-hydroxyphenyl)-2-hydroxy-4-oxobut-2-enoic acid, MAGNESIUM ION, Malate synthase G 著者 Krieger, I.V, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) 登録日 2017-10-12 公開日 2018-09-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.496 Å) 主引用文献 Anion-pi Interactions in Computer-Aided Drug Design: Modeling the Inhibition of Malate Synthase by Phenyl-Diketo Acids. J Chem Inf Model, 58, 2018
6BBX	Crystal structure of TnmS3 in complex with TNM C 分子名称: Glyoxalase/bleomycin resisance protein/dioxygenase, methyl (2R,3R)-2,3-dihydroxy-3-[(1aS,11S,11aR,14Z,18R)-3,7,8,18-tetrahydroxy-4,9-dioxo-4,9,10,11-tetrahydro-11aH-11,1a-hept[3]ene[1,5]diynonaphtho[2,3-h]oxireno[c]quinolin-11a-yl]butanoate 著者 Chang, C.Y, Chang, C, Nocek, B, Rudolf, J.D, Joachimiak, A, Phillips Jr, G.N, Shen, B, Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG) 登録日 2017-10-19 公開日 2018-07-04 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Resistance to Enediyne Antitumor Antibiotics by Sequestration. Cell Chem Biol, 25, 2018
5D9P	Crystal structure of PbGH5A, a glycoside hydrolase family 5 enzyme from Prevotella bryantii B14, in complex with an inhibitory N-bromoacetylglycosylamine derivative of XXXG 分子名称: B-1,4-endoglucanase, CALCIUM ION, alpha-D-xylopyranose-(1-6)-beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-N-acetyl-beta-D-glucopyranosylamine 著者 Morar, M, Stogios, P.J, Xu, X, Cui, H, Di Leo, R, Yim, V, Savchenko, A. 登録日 2015-08-18 公開日 2015-11-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure-Function Analysis of a Mixed-linkage beta-Glucanase/Xyloglucanase from the Key Ruminal Bacteroidetes Prevotella bryantii B14. J.Biol.Chem., 291, 2016
6BC2	Cryo X-ray structure of acetylsisomicin bound AAC-VIa 分子名称: AAC 3-VI protein, MAGNESIUM ION, acetylsisomicin 著者 Cuneo, M.J, Kumar, P, Serpersu, E.H. 登録日 2017-10-20 公開日 2018-02-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.195 Å) 主引用文献 A low-barrier hydrogen bond mediates antibiotic resistance in a noncanonical catalytic triad. Sci Adv, 4, 2018
6BC7	Cryo X-ray structure of sisomicin bound AAC-VIa 分子名称: (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, AAC 3-VI protein, ACETATE ION 著者 Cuneo, M.J, Kumar, P. 登録日 2017-10-20 公開日 2018-02-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A low-barrier hydrogen bond mediates antibiotic resistance in a noncanonical catalytic triad. Sci Adv, 4, 2018
5DD1	Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques 分子名称: ANTI-HIV ANTIBODY DH570 FAB HEAVY CHAIN, ANTI-HIV ANTIBODY DH570 FAB LIGHT CHAIN 著者 Zhang, R, Verkoczy, L, Wiehe, K, Alam, S.M, Nicely, N.I, Santra, S, Bradley, T, Pemble, C, Gao, F, Montefiori, D.C, Bouton-Verville, H, Kelsoe, G, Parks, R, Foulger, A, Tomaras, G, Keple, T.B, Moody, M.A, Liao, H.-X, Haynes, B.F. 登録日 2015-08-24 公開日 2016-05-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.597 Å) 主引用文献 Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages. Sci Transl Med, 8, 2016
6BFM	Galactose-binding Lectin from Mytilus californianus, Isoform1 分子名称: ACETATE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Hernandez-Santoyo, A, Garcia-Maldonado, E. 登録日 2017-10-26 公開日 2019-01-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.488 Å) 主引用文献 Glycan-induced oligomerization of a lectin from Mytilus californianus To Be Published
6AU7	Exploring Cystine Dense Peptide Space to Open a Unique Molecular Toolbox 分子名称: GLYCEROL, Potassium channel toxin gamma-KTx 2.2, SULFATE ION 著者 Gewe, M.M, Rupert, P, Strong, R.K. 登録日 2017-08-30 公開日 2018-02-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Screening, large-scale production and structure-based classification of cystine-dense peptides. Nat. Struct. Mol. Biol., 25, 2018
6CB5	Macrophage Migration Inhibitory Factor in complex with a Pyrazole Inhibitor (8g) 分子名称: 2-[(naphthalen-2-yl)oxy]-5-(1H-pyrazol-4-yl)benzoic acid, Macrophage migration inhibitory factor, SULFATE ION 著者 Krimmer, S.G, Robertson, M.J, Jorgensen, W.L. 登録日 2018-02-02 公開日 2018-04-04 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Optimization of Pyrazoles as Phenol Surrogates to Yield Potent Inhibitors of Macrophage Migration Inhibitory Factor. ChemMedChem, 13, 2018
6CR8	Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CHCL (R & S isomers), beta, gamma dATP analogue 分子名称: 5'-O-[(R)-{[(R)-[(R)-chloro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]-2'-deoxyadenosine, CHLORIDE ION, DNA polymerase beta, ... 著者 Batra, V.K, Wilson, S.H. 登録日 2018-03-16 公開日 2018-07-04 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs. Biochemistry, 57, 2018
5CYG	Crystal Structure of isoform 2 of uridine phosphorylase from Schistosoma mansoni APO form 分子名称: Putative uridine phosphorylase 著者 Romanello, L, Torini, J.R, DeMarco, R, Pereira, H.M. 登録日 2015-07-30 公開日 2016-03-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.017 Å) 主引用文献 Analysis of two Schistosoma mansoni uridine phosphorylases isoforms suggests the emergence of a protein with a non-canonical function. Biochimie, 125, 2016
6CVW	Crystal structure of HCV NS3/4A WT protease in complex with AJ-52 (MK-5172 linear analogue) 分子名称: N-[(cyclopentyloxy)carbonyl]-3-methyl-L-valyl-(4R)-N-[(1R,2S)-2-ethenyl-1-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}cyclopropyl]-4-[(7-methoxy-3-methylquinoxalin-2-yl)oxy]-L-prolinamide, NS3 protease, SULFATE ION, ... 著者 Matthew, A.N, Schiffer, C.A. 登録日 2018-03-29 公開日 2018-08-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Quinoxaline-Based Linear HCV NS3/4A Protease Inhibitors Exhibit Potent Activity against Drug Resistant Variants. ACS Med Chem Lett, 9, 2018
5AES	Crystal Structure of murine Chronophin (Pyridoxal Phosphate Phosphatase) in Complex with a PNP-derived Inhibitor 分子名称: GLYCEROL, MAGNESIUM ION, PYRIDOXAL PHOSPHATE PHOSPHATASE, ... 著者 Knobloch, G, Jabari, N, Koehn, M, Gohla, A, Schindelin, H. 登録日 2015-01-09 公開日 2015-04-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.751 Å) 主引用文献 Synthesis of Hydrolysis-Resistant Pyridoxal 5'-Phosphate Analogs and Their Biochemical and X-Ray Crystallographic Characterization with the Pyridoxal Phosphatase Chronophin. Bioorg.Med.Chem., 23, 2015
5BMP	Crystal Structure of Phosphoglucomutase from Xanthomonas citri complexed with glucose-1-phosphate 分子名称: 1-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, Phosphoglucomutase 著者 Goto, L.S, Pereira, H.M, Novo Mansur, M.T.M. 登録日 2015-05-22 公開日 2016-06-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural and functional characterization of the phosphoglucomutase from Xanthomonas citri subsp. citri. Biochim.Biophys.Acta, 1864, 2016
5BPV	Crystal Structure of Zaire ebolavirus VP35 RNA binding domain mutant I278A 分子名称: Polymerase cofactor VP35 著者 Fadda, V, Cannas, V, Zinzula, L, Distinto, S, Daino, G.L, Bianco, G, Corona, A, Esposito, F, Alcaro, S, Maccioni, E, Tramontano, E, Taylor, G.L. 登録日 2015-05-28 公開日 2016-06-29 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.952 Å) 主引用文献 Crystal Structure of Zaire ebolavirus VP35 RNA binding domain mutant I278A to be published
6CR6	Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CH-CH3, beta, gamma dATP analogue 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy({(R)-hydroxy[(1S)-1-phosphonoethyl]phosphoryl}oxy)phosphoryl]adenosine, DNA polymerase beta, Downstream Primer Strand, ... 著者 Batra, V.K, Wilson, S.H. 登録日 2018-03-16 公開日 2018-08-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.097 Å) 主引用文献 Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs. Biochemistry, 57, 2018
5GOK	K11/K63-branched tri-Ubiquitin 分子名称: D-ubiquitin, Ubiquitin 著者 Gao, S, Pan, M, Zheng, Y, Liu, L. 登録日 2016-07-27 公開日 2016-11-02 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Monomer/Oligomer Quasi-Racemic Protein Crystallography J.Am.Chem.Soc., 138, 2016

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