5AES
Crystal Structure of murine Chronophin (Pyridoxal Phosphate Phosphatase) in Complex with a PNP-derived Inhibitor
Summary for 5AES
Entry DOI | 10.2210/pdb5aes/pdb |
Descriptor | PYRIDOXAL PHOSPHATE PHOSPHATASE, MAGNESIUM ION, {2-[5-hydroxy-4-(hydroxymethyl)-6-methylpyridin-3-yl]ethyl}phosphonic acid, ... (5 entities in total) |
Functional Keywords | hydrolase, pdxp, plpp, haloacid dehalogenase, had phosphatase, had hydrolase |
Biological source | MUS MUSCULUS (HOUSE MOUSE) |
Cellular location | Cytoplasm, cytosol : P60487 |
Total number of polymer chains | 2 |
Total formula weight | 63864.93 |
Authors | Knobloch, G.,Jabari, N.,Koehn, M.,Gohla, A.,Schindelin, H. (deposition date: 2015-01-09, release date: 2015-04-01, Last modification date: 2024-01-10) |
Primary citation | Knobloch, G.,Jabari, N.,Stadlbauer, S.,Schindelin, H.,Kohn, M.,Gohla, A. Synthesis of Hydrolysis-Resistant Pyridoxal 5'-Phosphate Analogs and Their Biochemical and X-Ray Crystallographic Characterization with the Pyridoxal Phosphatase Chronophin. Bioorg.Med.Chem., 23:2819-, 2015 Cited by PubMed: 25783190DOI: 10.1016/J.BMC.2015.02.049 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.751 Å) |
Structure validation
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