5AES

Crystal Structure of murine Chronophin (Pyridoxal Phosphate Phosphatase) in Complex with a PNP-derived Inhibitor

Summary for 5AES

Entry DOI	10.2210/pdb5aes/pdb
Descriptor	PYRIDOXAL PHOSPHATE PHOSPHATASE, MAGNESIUM ION, {2-[5-hydroxy-4-(hydroxymethyl)-6-methylpyridin-3-yl]ethyl}phosphonic acid, ... (5 entities in total)
Functional Keywords	hydrolase, pdxp, plpp, haloacid dehalogenase, had phosphatase, had hydrolase
Biological source	MUS MUSCULUS (HOUSE MOUSE)
Cellular location	Cytoplasm, cytosol : P60487
Total number of polymer chains	2
Total formula weight	63864.93
Authors	Knobloch, G.,Jabari, N.,Koehn, M.,Gohla, A.,Schindelin, H. (deposition date: 2015-01-09, release date: 2015-04-01, Last modification date: 2024-01-10)
Primary citation	Knobloch, G.,Jabari, N.,Stadlbauer, S.,Schindelin, H.,Kohn, M.,Gohla, A. Synthesis of Hydrolysis-Resistant Pyridoxal 5'-Phosphate Analogs and Their Biochemical and X-Ray Crystallographic Characterization with the Pyridoxal Phosphatase Chronophin. Bioorg.Med.Chem., 23:2819-, 2015 Cited by PubMed: 25783190 DOI: 10.1016/J.BMC.2015.02.049 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.751 Å)

Structure validation