6CR6
Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CH-CH3, beta, gamma dATP analogue
Summary for 6CR6
Entry DOI | 10.2210/pdb6cr6/pdb |
Descriptor | Template Strand, Primer Strand, Downstream Primer Strand, ... (8 entities in total) |
Functional Keywords | conformational change, enzyme mechanism, lfer, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 48263.37 |
Authors | Batra, V.K.,Wilson, S.H. (deposition date: 2018-03-16, release date: 2018-08-22, Last modification date: 2023-10-04) |
Primary citation | Batra, V.K.,Oertell, K.,Beard, W.A.,Kashemirov, B.A.,McKenna, C.E.,Goodman, M.F.,Wilson, S.H. Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs. Biochemistry, 57:3934-3944, 2018 Cited by PubMed: 29874056DOI: 10.1021/acs.biochem.8b00418 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.097 Å) |
Structure validation
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