PDB: 1513 件ウェブページステータス検索Chemie searchBIRD

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6HMO	Solution structure of the RNA duplex formed by the 5'-end of U1snRNA and the 5'-splice site of SMN2 exon7 in complex with the SMN-C5 splicing modifier 分子名称: 2-(8-fluoranyl-2-methyl-imidazo[1,2-a]pyridin-6-yl)-7-(4-methylpiperazin-1-yl)pyrido[1,2-a]pyrimidin-4-one, RNA (5'-R(*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3') 著者 Campagne, S, Allain, F.H. 登録日 2018-09-12 公開日 2019-08-14 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural basis of a small molecule targeting RNA for a specific splicing correction. Nat.Chem.Biol., 15, 2019
6HHQ	Crystal structure of compound C45 bound to the yeast 80S ribosome 分子名称: (3~{R})-3-[(1~{S})-2-[(1~{S},4~{a}~{R},6~{S},7~{S},8~{a}~{R})-6,7-bis(chloranyl)-5,5,8~{a}-trimethyl-2-methylidene-3,4,4~{a},6,7,8-hexahydro-1~{H}-naphthalen-1-yl]-1-oxidanyl-ethyl]pyrrolidine-2,5-dione, 18S ribosomal RNA, 25S ribosomal RNA, ... 著者 Pellegrino, S, Vanderwal, C.D, Yusupov, M. 登録日 2018-08-28 公開日 2019-02-20 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (3.10000038 Å) 主引用文献 Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome. Nucleic Acids Res., 47, 2019
6GQV	Cryo-EM recosntruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GMPPCP) 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Pellegrino, S, Yusupov, M, Yusupova, G, Hashem, Y. 登録日 2018-06-08 公開日 2018-07-11 最終更新日 2018-08-08 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance. J. Mol. Biol., 430, 2018
6FT6	Structure of the Nop53 pre-60S particle bound to the exosome nuclear cofactors 分子名称: 25S ribosomal RNA, 5S ribosomal RNA, 60S ribosomal protein L11-A, ... 著者 Schuller, J.M, Falk, S, Conti, E. 登録日 2018-02-20 公開日 2018-03-28 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structure of the nuclear exosome captured on a maturing preribosome. Science, 360, 2018
1N0Z	Solution structure of the first zinc-finger domain from ZNF265 分子名称: ZINC ION, ZNF265 著者 Plambeck, C.A, Fairley, K, Kwan, A.H.Y, Westman, B.J, Adams, D, Morris, B, Mackay, J.P. 登録日 2002-10-15 公開日 2003-07-22 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 The structure of the zinc finger domain from human splicing factor ZNF265 fold J.BIOL.CHEM., 278, 2003
1PYS	PHENYLALANYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS 分子名称: MAGNESIUM ION, PHENYLALANYL-TRNA SYNTHETASE 著者 Safro, M, Mosyak, L, Goldgur, Y, Reshetnikova, L, Delarue, M. 登録日 1996-11-14 公開日 1997-11-19 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure of phenylalanyl-tRNA synthetase from Thermus thermophilus. Nat.Struct.Biol., 2, 1995
2K8Q	NMR Structure of Shq1p N-terminal domain 分子名称: Protein SHQ1 著者 Godin, K.S, Varani, G. 登録日 2008-09-18 公開日 2009-05-05 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 The box H/ACA snoRNP assembly factor Shq1p is a chaperone protein homologous to Hsp90 cochaperones that binds to the Cbf5p enzyme J.Mol.Biol., 390, 2009
6SN1	Crystal structure of the human INTS13-INTS14 complex 分子名称: Integrator complex subunit 13, Integrator complex subunit 14, SULFATE ION 著者 Jonas, S, Sabath, K, Staeubli, M.L. 登録日 2019-08-23 公開日 2020-07-22 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.54 Å) 主引用文献 INTS10-INTS13-INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module. Nat Commun, 11, 2020
5MKL	Crystal structure of SmAP (LSm) protein from Sulfolobus acidocaldarius 分子名称: Sm ribonucleo 著者 Nikulin, A.D, Lekontseva, N.V, Tishchenko, S.V. 登録日 2016-12-05 公開日 2017-12-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.086 Å) 主引用文献 Crystal structures and RNA-binding properties of Lsm proteins from archaea Sulfolobus acidocaldarius and Methanococcus vannielii: Similarity and difference of the U-binding mode. Biochimie, 175, 2020
7OH3	Nog1-TAP associated immature ribosomal particle population B from S. cerevisiae 分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Milkereit, P, Poell, G. 登録日 2021-05-08 公開日 2021-11-03 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors. Plos One, 16, 2021
7OHQ	Nog1-TAP associated immature ribosomal particle population C from S. cerevisiae 分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Milkereit, P, Poell, G. 登録日 2021-05-11 公開日 2021-11-03 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors. Plos One, 16, 2021
3BO4	A relaxed active site following exon ligation by a group I intron 分子名称: DNA/RNA (5'-R(*AP*AP*GP*CP*CP*AP*CP*AP*CP*AP*AP*AP*CP*CP*A)-D(P*DG)-3'), DNA/RNA (5'-R(*CP*A)-D(P*DU)-R(P*AP*CP*GP*GP*CP*C)-3'), Group I intron P9, ... 著者 Lipchock, S.V, Strobel, S.A. 登録日 2007-12-17 公開日 2008-04-01 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.33 Å) 主引用文献 A relaxed active site after exon ligation by the group I intron Proc.Natl.Acad.Sci.Usa, 105, 2008
3BO3	A relaxed active site following exon ligation by a group I intron 分子名称: Group I intron P9, MAGNESIUM ION, POTASSIUM ION, ... 著者 Lipchock, S.V, Strobel, S.A. 登録日 2007-12-17 公開日 2008-04-01 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 A relaxed active site after exon ligation by the group I intron Proc.Natl.Acad.Sci.Usa, 105, 2008
7OF1	Nog1-TAP associated immature ribosomal particle population A from S. cerevisiae 分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Milkereit, P, Poell, G. 登録日 2021-05-04 公開日 2021-11-03 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors. Plos One, 16, 2021
7OHR	Nog1-TAP associated immature ribosomal particle population E from S. cerevisiae 分子名称: 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... 著者 Milkereit, P, Poell, G. 登録日 2021-05-11 公開日 2021-11-10 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (4.72 Å) 主引用文献 Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors. Plos One, 16, 2021
3BWP	Crystal structure of a self-spliced group II intron 分子名称: Group IIC intron, MAGNESIUM ION, POTASSIUM ION 著者 Toor, N, Keating, K.S, Taylor, S.D, Pyle, A.M. 登録日 2008-01-10 公開日 2008-04-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal structure of a self-spliced group II intron Science, 320, 2008
1XTQ	Structure of small GTPase human Rheb in complex with GDP 分子名称: GTP-binding protein Rheb, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION 著者 Yu, Y, Ding, J. 登録日 2004-10-24 公開日 2005-03-08 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Basis for the Unique Biological Function of Small GTPase RHEB J.Biol.Chem., 280, 2005
7P6X	Cryo-Em structure of the hexameric RUVBL1-RUVBL2 in complex with ZNHIT2 分子名称: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2 著者 Llorca, O, Serna, M, Fernandez-Leiro, R. 登録日 2021-07-18 公開日 2021-12-15 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 CryoEM of RUVBL1-RUVBL2-ZNHIT2, a complex that interacts with pre-mRNA-processing-splicing factor 8. Nucleic Acids Res., 50, 2022
7OYA	Cryo-EM structure of the 1 hpf zebrafish embryo 80S ribosome 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... 著者 Leesch, F, Lorenzo-Orts, L, Grishkovskaya, I, Kandolf, S, Belacic, K, Meinhart, A, Haselbach, D, Pauli, A. 登録日 2021-06-24 公開日 2022-07-13 最終更新日 2023-02-08 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 A molecular network of conserved factors keeps ribosomes dormant in the egg. Nature, 613, 2023
7OYB	Cryo-EM structure of the 6 hpf zebrafish embryo 80S ribosome 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... 著者 Leesch, F, Lorenzo-Orts, L, Grishkovskaya, I, Kandolf, S, Belacic, K, Meinhart, A, Haselbach, D, Pauli, A. 登録日 2021-06-24 公開日 2022-07-13 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 A molecular network of conserved factors keeps ribosomes dormant in the egg. Nature, 613, 2023
4O2R	Structure of Mus musculus Rheb G63V mutant bound to GDP 分子名称: GTP-binding protein Rheb, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION 著者 Mazhab-Jafari, M.T, Marshall, C.B, Ho, J, Ishiyama, N, Stambolic, V, Ikura, M. 登録日 2013-12-17 公開日 2014-03-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure-guided mutation of the conserved G3-box glycine in Rheb generates a constitutively activated regulator of mammalian target of rapamycin (mTOR). J.Biol.Chem., 289, 2014
4RG5	Crystal Structure of S. Pombe SMN YG-Dimer 分子名称: MALONATE ION, Maltose-binding periplasmic protein, Survival Motor Neuron protein chimera, ... 著者 Gupta, K, Martin, R.S, Sarachan, K.L, Sharp, B, Van Duyne, G.D. 登録日 2014-09-29 公開日 2015-07-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Oligomeric Properties of Survival Motor NeuronGemin2 Complexes. J.Biol.Chem., 290, 2015
4ROE	Human TFIIB-related factor 2 (Brf2) and TBP bound to RPPH1 promoter 分子名称: MAGNESIUM ION, Non-template strand, TATA-box-binding protein, ... 著者 Vannini, A, Gouge, J, Satia, K, Guthertz, N. 登録日 2014-10-28 公開日 2015-12-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2. Cell(Cambridge,Mass.), 163, 2015
5NDG	Crystal structure of geneticin (G418) bound to the yeast 80S ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G. 登録日 2017-03-08 公開日 2017-12-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 Aminoglycoside interactions and impacts on the eukaryotic ribosome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5NDV	Crystal structure of Paromomycin bound to the yeast 80S ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G. 登録日 2017-03-09 公開日 2017-12-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Aminoglycoside interactions and impacts on the eukaryotic ribosome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017

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