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6SN1

Crystal structure of the human INTS13-INTS14 complex

Summary for 6SN1
Entry DOI10.2210/pdb6sn1/pdb
DescriptorIntegrator complex subunit 13, Integrator complex subunit 14, SULFATE ION, ... (4 entities in total)
Functional Keywordsintegrator, interlocked chains, vwa, pseudosymmetrical heterodimer, rna binding protein
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight144172.24
Authors
Jonas, S.,Sabath, K.,Staeubli, M.L. (deposition date: 2019-08-23, release date: 2020-07-22)
Primary citationSabath, K.,Staubli, M.L.,Marti, S.,Leitner, A.,Moes, M.,Jonas, S.
INTS10-INTS13-INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module.
Nat Commun, 11:3422-3422, 2020
Cited by
PubMed: 32647223
DOI: 10.1038/s41467-020-17232-2
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.54 Å)
Structure validation

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