7P6X

Cryo-Em structure of the hexameric RUVBL1-RUVBL2 in complex with ZNHIT2

Summary for 7P6X

• Entry DOI: 10.2210/pdb7p6x/pdb
• EMDB information: 13233
• Descriptor: RuvB-like 1, RuvB-like 2, ADENOSINE-5'-DIPHOSPHATE (3 entities in total)
• Functional Keywords: u5 assembly, protein complex assembly, r2tp, cochaperone, spliceosome, splicing
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 305839.74

Authors

Llorca, O.,Serna, M.,Fernandez-Leiro, R. (deposition date: 2021-07-18, release date: 2021-12-15, Last modification date: 2023-01-25)

• Primary citation: Serna, M.,Gonzalez-Corpas, A.,Cabezudo, S.,Lopez-Perrote, A.,Degliesposti, G.,Zarzuela, E.,Skehel, J.M.,Munoz, J.,Llorca, O.; CryoEM of RUVBL1-RUVBL2-ZNHIT2, a complex that interacts with pre-mRNA-processing-splicing factor 8.; Nucleic Acids Res., 50:1128-1146, 2022; PubMed: 34951455; DOI: 10.1093/nar/gkab1267

Experimental method

ELECTRON MICROSCOPY (4.1 Å)