PDB: 19952 件ウェブページステータス検索Chemie searchBIRD

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6Y0F	Structure of human FAPalpha in complex with linagliptin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 8-[(3R)-3-Aminopiperidin-1-yl]-7-but-2-yn-1-yl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-3,7-dihydro-1H-purine-2,6-d ione, ... 著者 Nar, H, Schnapp, G, Schreiner, P. 登録日 2020-02-07 公開日 2021-02-17 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.924 Å) 主引用文献 Structure of human FAPalpha in complex with linagliptin To Be Published
2XUI	CRYSTAL STRUCTURE OF MACHE-Y337A-TZ2PA6 SYN COMPLEX (1 WK) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3,8-DIAMINO-6-PHENYL-5-[6-[1-[2-[(1,2,3,4-TETRAHYDRO-9-ACRIDINYL)AMINO]ETHYL]-1H-1,2,3-TRIAZOL-5-YL]HEXYL]-PHENANTHRIDINIUM, ACETYLCHOLINESTERASE, ... 著者 Bourne, Y, Radic, Z, Taylor, P, Marchot, P. 登録日 2010-10-19 公開日 2010-12-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Conformational Remodeling of Femtomolar Inhibitor-Acetylcholinesterase Complexes in the Crystalline State J.Am.Chem.Soc., 132, 2010
2XUG	Crystal structure of mAChE-Y337A-TZ2PA6 anti complex (1 wk) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3,8-DIAMINO-6-PHENYL-5-[6-[1-[2-[(1,2,3,4-TETRAHYDRO-9-ACRIDINYL)AMINO]ETHYL]-1H-1,2,3-TRIAZOL-4-YL]HEXYL]-PHENANTHRIDINIUM, ACETYLCHOLINESTERASE, ... 著者 Bourne, Y, Radic, Z, Taylor, P, Marchot, P. 登録日 2010-10-19 公開日 2010-12-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Conformational Remodeling of Femtomolar Inhibitor-Acetylcholinesterase Complexes in the Crystalline State J.Am.Chem.Soc., 132, 2010
2GOL	Xray Structure of Gag278 分子名称: Capsid protein p24 (CA), Matrix protein p17 (MA), SULFATE ION 著者 Kelly, B.N. 登録日 2006-04-13 公開日 2006-09-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Implications for Viral Capsid Assembly from Crystal Structures of HIV-1 Gag 1-278 and CAN 133-278. Biochemistry, 45, 2006
2HDE	Solution Structure of Human SAP18 分子名称: Histone deacetylase complex subunit SAP18 著者 McCallum, S.A, Yin, J.P, Pan, B, Fairbrother, W.J. 登録日 2006-06-20 公開日 2007-04-24 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structure of SAP18: a ubiquitin fold in histone deacetylase complex assembly. Biochemistry, 45, 2006
8K2B	Cryo-EM structure of the human 39S mitoribosome with Tigecycline 分子名称: 16s rRNA, 39S ribosomal protein L22, mitochondrial, ... 著者 Li, X, Wang, M, Cheng, J. 登録日 2023-07-12 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
8K4E	Cryo-EM structure of 30S ribosome with cleaved AP-mRNA bound complex-II 分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Ramachandran, R, Afsar, M, Shukla, A. 登録日 2023-07-18 公開日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Cryo-EM structure of 30S ribosome with cleaved AP-mRNA bound complex-II To Be Published
8K2A	Cryo-EM structure of the human 55S mitoribosome with Tigecycline 分子名称: 12S rRNA, 16S rRNA, 39S ribosomal protein L22, ... 著者 Li, X, Wang, M, Cheng, J. 登録日 2023-07-12 公開日 2024-07-10 最終更新日 2024-10-09 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
6XGF	Escherichia coli transcription-translation complex B (TTC-B) containing an 30 nt long mRNA spacer, NusG, and fMet-tRNAs at E-site and P-site 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... 著者 Molodtsov, V, Wang, C, Su, M, Ebright, R.H. 登録日 2020-06-17 公開日 2020-09-02 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (5 Å) 主引用文献 Structural basis of transcription-translation coupling. Science, 369, 2020
8K3O	Cryo-EM structure of 30S ribosome with cleaved AP-mRNA bound complex I 分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Afsar, M, Shukla, A, Ramachandran, R. 登録日 2023-07-16 公開日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.88 Å) 主引用文献 Cryo-EM structure of 30S ribosome with cleaved AP-mRNA bound complex I To Be Published
2H6I	W102T/Y365F Protein Farnesyltransferase Double Mutant Complexed with a Geranylgeranylated DDPTASACVLS Peptide Product at 3.0A 分子名称: GERAN-8-YL GERAN, Protein farnesyltransferase beta subunit, Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit, ... 著者 Terry, K.L, Beese, L.S. 登録日 2006-05-31 公開日 2006-08-29 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Conversion of protein farnesyltransferase to a geranylgeranyltransferase. Biochemistry, 45, 2006
8OIR	55S human mitochondrial ribosome with mtRF1 and P-site tRNA 分子名称: 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ... 著者 Saurer, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Ban, N. 登録日 2023-03-23 公開日 2023-06-14 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Molecular basis of translation termination at noncanonical stop codons in human mitochondria. Science, 380, 2023
8OIN	55S mammalian mitochondrial ribosome with mtRF1 and P-site tRNA 分子名称: 12S rRNA, 16S rRNA, 28S ribosomal protein S15, ... 著者 Saurer, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Ban, N. 登録日 2023-03-23 公開日 2023-06-14 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Molecular basis of translation termination at noncanonical stop codons in human mitochondria. Science, 380, 2023
6XTX	CryoEM structure of human CMG bound to ATPgammaS and DNA 分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45 homolog, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), ... 著者 Rzechorzek, N.J, Pellegrini, L. 登録日 2020-01-16 公開日 2020-05-27 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.29 Å) 主引用文献 CryoEM structures of human CMG-ATP gamma S-DNA and CMG-AND-1 complexes. Nucleic Acids Res., 48, 2020
6X9Q	Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B3 (TTC-B3) containing an mRNA with a 27 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... 著者 Molodtsov, V, Ebright, R.H, Wang, C, Su, M. 登録日 2020-06-03 公開日 2020-09-02 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 Structural basis of transcription-translation coupling. Science, 369, 2020
8PEG	Escherichia coli paused disome complex (queueing 70S non-rotated closed PRE state) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S1, ... 著者 Fluegel, T, Schacherl, M. 登録日 2023-06-13 公開日 2024-03-06 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Transient disome complex formation in native polysomes during ongoing protein synthesis captured by cryo-EM. Nat Commun, 15, 2024
8PKL	Escherichia coli paused disome complex (leading 70S non-rotated closed PRE state) 分子名称: 1,4-DIAMINOBUTANE, 16S ribosomal RNA, 23S ribosomal RNA, ... 著者 Fluegel, T, Schacherl, M. 登録日 2023-06-26 公開日 2024-03-06 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (3.09 Å) 主引用文献 Transient disome complex formation in native polysomes during ongoing protein synthesis captured by cryo-EM. Nat Commun, 15, 2024
2GCP	Crystal structure of the human RhoC-GSP complex 分子名称: 1,2-ETHANEDIOL, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, ... 著者 Dias, S.M.G, Cerione, R.A. 登録日 2006-03-14 公開日 2007-03-27 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 X-ray Crystal Structures Reveal Two Activated States for RhoC. Biochemistry, 46, 2007
2XUF	CRYSTAL STRUCTURE OF MACHE-Y337A-TZ2PA6 ANTI COMPLEX (1 MTH) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3,8-DIAMINO-6-PHENYL-5-[6-[1-[2-[(1,2,3,4-TETRAHYDRO-9-ACRIDINYL)AMINO]ETHYL]-1H-1,2,3-TRIAZOL-4-YL]HEXYL]-PHENANTHRIDINIUM, ACETYLCHOLINESTERASE, ... 著者 Bourne, Y, Radic, Z, Taylor, P, Marchot, P. 登録日 2010-10-19 公開日 2010-12-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Conformational Remodeling of Femtomolar Inhibitor-Acetylcholinesterase Complexes in the Crystalline State J.Am.Chem.Soc., 132, 2010
2XQN	Complex of the 2nd and 3rd LIM domains of TES with the EVH1 DOMAIN of MENA and the N-Terminal domain of actin-like protein Arp7A 分子名称: ACTIN-LIKE PROTEIN 7A, ENABLED HOMOLOG, TESTIN, ... 著者 Knowles, P.P, Briggs, D.C, Murray-Rust, J, McDonald, N.Q. 登録日 2010-09-03 公開日 2011-01-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Molecular recognition of the Tes LIM2-3 domains by the actin-related protein Arp7A. J. Biol. Chem., 286, 2011
2XUJ	CRYSTAL STRUCTURE OF MACHE-Y337A-TZ2PA6 SYN COMPLEX (1 MTH) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3,8-DIAMINO-6-PHENYL-5-[6-[1-[2-[(1,2,3,4-TETRAHYDRO-9-ACRIDINYL)AMINO]ETHYL]-1H-1,2,3-TRIAZOL-5-YL]HEXYL]-PHENANTHRIDINIUM, ACETYLCHOLINESTERASE, ... 著者 Bourne, Y, Radic, Z, Taylor, P, Marchot, P. 登録日 2010-10-19 公開日 2010-12-08 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Conformational Remodeling of Femtomolar Inhibitor-Acetylcholinesterase Complexes in the Crystalline State J.Am.Chem.Soc., 132, 2010
2Y2V	Nonaged form of Mouse Acetylcholinesterase inhibited by sarin-Update 分子名称: 1-ETHOXY-2-(2-METHOXYETHOXY)ETHANE, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, 2-ETHOXYETHANOL, ... 著者 Akfur, C, Artursson, E, Ekstrom, F. 登録日 2010-12-16 公開日 2011-11-30 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Methylphosphonate Adducts of Acetylcholinesterase Investigated by Time Correlated Single Photon Counting and X-Ray Crystallography To be Published
8OO6	Pol I bound to extended and displaced DNA section - closed conformation 分子名称: DNA polymerase I, Displaced primer, Extending Primer, ... 著者 Botto, M, Borsellini, A, Lamers, M.H. 登録日 2023-04-04 公開日 2023-08-09 最終更新日 2023-11-01 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 A four-point molecular handover during Okazaki maturation. Nat.Struct.Mol.Biol., 30, 2023
8OOY	Pol I bound to extended and displaced DNA section - open conformation 分子名称: DNA polymerase I, Displacing Primer, Extending Primer, ... 著者 Botto, M, Borsellini, A, Lamers, M.H. 登録日 2023-04-06 公開日 2023-08-09 最終更新日 2023-11-01 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 A four-point molecular handover during Okazaki maturation. Nat.Struct.Mol.Biol., 30, 2023
8OUW	Cryo-EM structure of CMG helicase bound to TIM-1/TIPN-1 and homodimeric DNSN-1 on fork DNA (Caenorhabditis elegans) 分子名称: Cell division control protein 45 homolog, DNA Lagging Strand Template, DNA Leading Strand Template, ... 著者 Jenkyn-Bedford, M, Yeeles, J.T.P, Labib, K.P.M. 登録日 2023-04-25 公開日 2023-08-16 最終更新日 2023-10-04 実験手法 ELECTRON MICROSCOPY (3.75 Å) 主引用文献 DNSN-1 recruits GINS for CMG helicase assembly during DNA replication initiation in Caenorhabditis elegans. Science, 381, 2023

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