8K2A
Cryo-EM structure of the human 55S mitoribosome with Tigecycline
This is a non-PDB format compatible entry.
Summary for 8K2A
Entry DOI | 10.2210/pdb8k2a/pdb |
EMDB information | 36836 |
Descriptor | 16S rRNA, Large ribosomal subunit protein uL14m, Large ribosomal subunit protein uL15m, ... (87 entities in total) |
Functional Keywords | 55s mitoribosome, tigecycline, antibiotic, ribosome |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 83 |
Total formula weight | 2889198.22 |
Authors | |
Primary citation | Li, X.,Wang, M.,Denk, T.,Buschauer, R.,Li, Y.,Beckmann, R.,Cheng, J. Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15:5481-5481, 2024 Cited by PubMed: 38942792DOI: 10.1038/s41467-024-49797-7 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
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