8OUW
Cryo-EM structure of CMG helicase bound to TIM-1/TIPN-1 and homodimeric DNSN-1 on fork DNA (Caenorhabditis elegans)
This is a non-PDB format compatible entry.
Summary for 8OUW
| Entry DOI | 10.2210/pdb8ouw/pdb |
| EMDB information | 17204 |
| Descriptor | DNA replication licensing factor MCM2, DNA replication complex GINS protein SLD5, Cell division control protein 45 homolog, ... (19 entities in total) |
| Functional Keywords | dna replication, dna replication initiation, replisome, donson, replication |
| Biological source | Caenorhabditis elegans More |
| Total number of polymer chains | 19 |
| Total formula weight | 1153734.08 |
| Authors | Jenkyn-Bedford, M.,Yeeles, J.T.P.,Labib, K.P.M. (deposition date: 2023-04-25, release date: 2023-08-16, Last modification date: 2023-10-04) |
| Primary citation | Xia, Y.,Sonneville, R.,Jenkyn-Bedford, M.,Ji, L.,Alabert, C.,Hong, Y.,Yeeles, J.T.P.,Labib, K.P.M. DNSN-1 recruits GINS for CMG helicase assembly during DNA replication initiation in Caenorhabditis elegans. Science, 381:eadi4932-eadi4932, 2023 Cited by PubMed: 37590372DOI: 10.1126/science.adi4932 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.75 Å) |
Structure validation
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