PDB: 37819 件ウェブページステータス検索Chemie searchBIRD

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3MMS	Crystal structure of Streptococcus pneumoniae MTA/SAH nucleosidase in complex with 8-aminoadenine 分子名称: 5'-methylthioadenosine / S-adenosylhomocysteine nucleosidase, 9H-purine-6,8-diamine, GLYCEROL 著者 Siu, K.K.W, Lee, J.E, Horvatin-Mrakovcic, C, Howell, P.L. 登録日 2010-04-20 公開日 2010-05-12 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of Streptococcus pneumoniae MTA/SAH nucleosidase in complex with 8-aminoadenine TO BE PUBLISHED
5GVQ	Solution structure of the first RRM domain of human spliceosomal protein SF3b49 分子名称: Splicing factor 3B subunit 4 著者 Kuwasako, K, Nameki, N, Tsuda, K, Takahashi, M, Sato, A, Tochio, N, Inoue, M, Terada, T, Kigawa, T, Kobayashi, N, Shirouzu, M, Ito, T, Sakamoto, T, Wakamatsu, K, Guntert, P, Takahashi, S, Yokoyama, S, Muto, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2016-09-06 公開日 2017-04-12 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution structure of the first RNA recognition motif domain of human spliceosomal protein SF3b49 and its mode of interaction with a SF3b145 fragment. Protein Sci., 26, 2017
5FIU	Binding and structural studies of a 5,5-difluoromethyl adenosine nucleoside with the fluorinase enzyme 分子名称: 5'-FLUORO-5'-DEOXY-ADENOSINE SYNTHASE, 5,5-DIFLUOROMETHYL ADENOSINE, L(+)-TARTARIC ACID 著者 Thompson, S, McMahon, S.A, Naismith, J.H, O'Hagan, D. 登録日 2015-10-02 公開日 2015-12-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Exploration of a Potential Difluoromethyl-Nucleoside Substrate with the Fluorinase Enzyme. Bioorg.Chem., 64, 2015
7B9C	Structure of a minimal SF3B core in complex with spliceostatin A (form I) 分子名称: PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, Splicing factor 3B subunit 3, ... 著者 Cretu, C, Pena, V. 登録日 2020-12-14 公開日 2021-08-04 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors. Nat Commun, 12, 2021
1M18	LIGAND BINDING ALTERS THE STRUCTURE AND DYNAMICS OF NUCLEOSOMAL DNA 分子名称: Histone H2A.1, Histone H2B.1, Histone H3.2, ... 著者 Suto, R.K, Edayathumangalam, R.S, White, C.L, Melander, C, Gottesfeld, J.M, Dervan, P.B, Luger, K. 登録日 2002-06-18 公開日 2003-02-18 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal Structures of Nucleosome Core Particles in Complex with Minor Groove DNA-binding Ligands J.Mol.Biol., 326, 2003
1M1A	LIGAND BINDING ALTERS THE STRUCTURE AND DYNAMICS OF NUCLEOSOMAL DNA 分子名称: 3-AMINO-(DIMETHYLPROPYLAMINE), 4-AMINO-(1-METHYLIMIDAZOLE)-2-CARBOXYLIC ACID, 4-AMINO-(1-METHYLPYRROLE)-2-CARBOXYLIC ACID, ... 著者 Suto, R.K, Edayathumangalam, R.S, White, C.L, Melander, C, Gottesfeld, J.M, Dervan, P.B, Luger, K. 登録日 2002-06-18 公開日 2003-02-18 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Crystal Structures of Nucleosome Core Particles in Complex with Minor Groove DNA-binding Ligands J.MOL.BIOL., 326, 2003
1HIY	Binding of nucleotides to NDP kinase 分子名称: 3'-DEOXY 3'-AMINO ADENOSINE-5'-DIPHOSPHATE, NUCLEOSIDE DIPHOSPHATE KINASE 著者 Cervoni, L, Lascu, I, Xu, Y, Gonin, P, Morr, M, Merouani, M, Janin, J, Giartoso, A. 登録日 2001-01-05 公開日 2001-05-31 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Binding of Nucleotides to Nucleoside Diphosphate Kinase: A Calorimetric Study. Biochemistry, 40, 2001
5VZ4	Receptor-growth factor crystal structure at 2.20 Angstrom resolution 分子名称: 1,2-ETHANEDIOL, BROMIDE ION, GDNF family receptor alpha-like, ... 著者 Lakshminarasimhan, D, White, A, Suto, R.K. 登録日 2017-05-26 公開日 2017-09-27 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15. Nature, 550, 2017
7JOA	2:1 cGAS-nucleosome complex 分子名称: Cyclic GMP-AMP synthase, DNA (145-MER), Histone H2A type 1, ... 著者 Boyer, J.A, Spangler, C.J, Strauss, J.D, Cesmat, A.P, Liu, P, McGinty, R.K, Zhang, Q. 登録日 2020-08-06 公開日 2020-09-16 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural basis of nucleosome-dependent cGAS inhibition. Science, 370, 2020
5W2E	HCV NS5B RNA-dependent RNA polymerase in complex with non-nucleoside inhibitor MK-8876 分子名称: 2-(4-fluorophenyl)-5-(11-fluoro-6H-pyrido[2',3':5,6][1,3]oxazino[3,4-a]indol-2-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide, Genome polyprotein 著者 Lesburg, C.A, Ummat, A. 登録日 2017-06-06 公開日 2017-08-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Development of a New Structural Class of Broadly Acting HCV Non-Nucleoside Inhibitors Leading to the Discovery of MK-8876. ChemMedChem, 12, 2017
1KX3	X-Ray Structure of the Nucleosome Core Particle, NCP146, at 2.0 A Resolution 分子名称: DNA (5'(ATCAATATCCACCTGCAGATTCTACCAAAAGTGTATTTGGAAACTGCTCCATCAAAAGGCATGTTCAGCTGAATTCAGCTGAACATGCCTTTTGATGGAGCAGTTTCCAAATACACTTTTGGTAGAATCTGCAGGTGGATATTGAT)3'), MANGANESE (II) ION, histone H2A.1, ... 著者 Davey, C.A, Sargent, D.F, Luger, K, Maeder, A.W, Richmond, T.J. 登録日 2002-01-31 公開日 2002-12-25 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Solvent Mediated Interactions in the Structure of the Nucleosome Core Particle at 1.9 A Resolution J.Mol.Biol., 319, 2002
1KX4	X-Ray Structure of the Nucleosome Core Particle, NCP146b, at 2.6 A Resolution 分子名称: CHLORIDE ION, DNA (5'(ATCTCCAAATATCCCTTGCGGATCGTAGAAAAAGTGTGTCAAACTGCGCTATCAAAGGGAAACTTCAACTGAATTCAGTTGAAGTTTCCCTTTGATAGCGCAGTTTGACACACTTTTTCTACGATCCGCAAGGGATATTTGGAGAT)3'), MANGANESE (II) ION, ... 著者 Davey, C.A, Sargent, D.F, Luger, K, Maeder, A.W, Richmond, T.J. 登録日 2002-01-31 公開日 2002-12-25 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Solvent Mediated Interactions in the Structure of the Nucleosome Core Particle at 1.9 A Resolution J.Mol.Biol., 319, 2002
6A5L	RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA 分子名称: DNA (198-MER), DNA (42-MER), DNA-directed RNA polymerase subunit, ... 著者 Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. 登録日 2018-06-24 公開日 2018-10-03 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (5.6 Å) 主引用文献 Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
6PVU	RNase A in complex with hexametaphosphate 分子名称: 2,4,6,8,10,12-hexahydroxy-2lambda~5~,4lambda~5~,6lambda~5~,8lambda~5~,10lambda~5~,12lambda~5~-cyclohexaphosphoxane-2,4,6,8,10,12-hexone, Ribonuclease pancreatic 著者 Windsor, I.W, Sheppard, S.M, Cummins, C.C, Raines, R.T. 登録日 2019-07-21 公開日 2019-11-06 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Nucleoside Tetra- and Pentaphosphates Prepared Using a Tetraphosphorylation Reagent Are Potent Inhibitors of Ribonuclease A. J.Am.Chem.Soc., 141, 2019
6PVW	RNase A in complex with cp4pA 分子名称: 2,4,6,8-tetrahydroxy-1,3,5,7,2lambda~5~,4lambda~5~,6lambda~5~,8lambda~5~-tetroxatetraphosphocane-2,4,6,8-tetrone, 5'-O-[(R)-hydroxy{[(4R,8S)-4,6,8-trihydroxy-2,4,6,8-tetraoxo-1,3,5,7,2lambda~5~,4lambda~5~,6lambda~5~,8lambda~5~-tetroxatetraphosphocan-2-yl]oxy}phosphoryl]adenosine, Ribonuclease pancreatic 著者 Windsor, I.W, Sheppard, S.M, Cummins, C.C, Raines, R.T. 登録日 2019-07-21 公開日 2019-11-06 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Nucleoside Tetra- and Pentaphosphates Prepared Using a Tetraphosphorylation Reagent Are Potent Inhibitors of Ribonuclease A. J.Am.Chem.Soc., 141, 2019
6A5R	RNA polymerase II elongation complex stalled at SHL(-2) of the nucleosome 分子名称: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... 著者 Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. 登録日 2018-06-25 公開日 2018-10-03 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (8.7 Å) 主引用文献 Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
5VZ3	Growth Factor Crystal Structure at 1.97 Angstrom Resolution 分子名称: Growth/differentiation factor 15 著者 Lakshminarasimhan, D, White, A, Suto, R.K. 登録日 2017-05-26 公開日 2017-09-27 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15. Nature, 550, 2017
6A5T	RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome 分子名称: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... 著者 Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. 登録日 2018-06-25 公開日 2018-10-03 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (6.7 Å) 主引用文献 Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
6A5P	RNA polymerase II elongation complex stalled at SHL(-5) of the nucleosome 分子名称: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... 著者 Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. 登録日 2018-06-25 公開日 2018-10-03 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (7 Å) 主引用文献 Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
6A5U	RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA, tilt conformation 分子名称: DNA (198-MER), DNA (40-MER), DNA-directed RNA polymerase subunit, ... 著者 Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. 登録日 2018-06-25 公開日 2018-10-03 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (7.6 Å) 主引用文献 Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
6PVX	RNase A in complex with p5U 分子名称: 5'-O-[(R)-hydroxy{[(S)-hydroxy{[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]oxy}phosphoryl]uridine, Ribonuclease pancreatic 著者 Windsor, I.W, Sheppard, S.M, Cummins, C.C, Raines, R.T. 登録日 2019-07-21 公開日 2019-11-06 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Nucleoside Tetra- and Pentaphosphates Prepared Using a Tetraphosphorylation Reagent Are Potent Inhibitors of Ribonuclease A. J.Am.Chem.Soc., 141, 2019
7JO9	1:1 cGAS-nucleosome complex 分子名称: Cyclic GMP-AMP synthase, DNA (145-MER), Histone H2A type 1, ... 著者 Boyer, J.A, Spangler, C.J, Strauss, J.D, Cesmat, A.P, Liu, P, McGinty, R.K, Zhang, Q. 登録日 2020-08-06 公開日 2020-09-16 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural basis of nucleosome-dependent cGAS inhibition. Science, 370, 2020
5IOM	Crystal Structure of Nucleoside Diphosphate Kinase from Schistosoma mansoni is space group P6322 分子名称: Nucleoside diphosphate kinase 著者 Torini, J.R.S, Romanello, L, Bird, L.E, Nettleship, J.E, Owens, R.J, Aller, P, DeMarco, R, Brandao-Neto, J, Pereira, H.M. 登録日 2016-03-08 公開日 2017-08-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Characterization of a Schistosoma mansoni NDPK expressed in sexual and digestive organs. Mol.Biochem.Parasitol., 2019
6A5O	RNA polymerase II elongation complex stalled at SHL(-6) of the nucleosome 分子名称: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... 著者 Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H. 登録日 2018-06-25 公開日 2018-10-03 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (9.9 Å) 主引用文献 Structural basis of the nucleosome transition during RNA polymerase II passage. Science, 362, 2018
2PYO	Drosophila nucleosome core 分子名称: CHLORIDE ION, DNA (147-MER), Histone H2A, ... 著者 Clapier, C.R, Petosa, C, Mueller, C.W. 登録日 2007-05-16 公開日 2007-11-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Structure of the Drosophila nucleosome core particle highlights evolutionary constraints on the H2A-H2B histone dimer. Proteins, 71, 2007

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