6A5P

RNA polymerase II elongation complex stalled at SHL(-5) of the nucleosome

Summary for 6A5P

EMDB information6982
DescriptorDNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, RNA polymerase II third largest subunit B44, part of central core, ... (21 entities in total)
Functional Keywordsnucleosome, chromatin, rna polymerase, transcription, transcription-rna-dna complex, transcription/rna/dna
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains23
Total molecular weight748737.46
Authors
Kujirai, T.,Ehara, H.,Fujino, Y.,Shirouzu, M.,Sekine, S.,Kurumizaka, H. (deposition date: 2018-06-25, release date: 2018-10-03, Last modification date: 2018-11-14)
Primary citation
Kujirai, T.,Ehara, H.,Fujino, Y.,Shirouzu, M.,Sekine, S.I.,Kurumizaka, H.
Structural basis of the nucleosome transition during RNA polymerase II passage.
Science, 362:595-598, 2018
PubMed: 30287617 (PDB entries with the same primary citation)
DOI: 10.1126/science.aau9904
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
?

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone10 0.2% 0.9% 0.43MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures