Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6A5P

RNA polymerase II elongation complex stalled at SHL(-5) of the nucleosome

Functional Information from GO Data
ChainGOidnamespacecontents
A0000428cellular_componentDNA-directed RNA polymerase complex
A0001055molecular_functionRNA polymerase II activity
A0003677molecular_functionDNA binding
A0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
A0005634cellular_componentnucleus
A0005665cellular_componentRNA polymerase II, core complex
A0006351biological_processDNA-templated transcription
A0006366biological_processtranscription by RNA polymerase II
A0016740molecular_functiontransferase activity
A0016779molecular_functionnucleotidyltransferase activity
A0034062molecular_function5'-3' RNA polymerase activity
A0046872molecular_functionmetal ion binding
B0000428cellular_componentDNA-directed RNA polymerase complex
B0001055molecular_functionRNA polymerase II activity
B0003677molecular_functionDNA binding
B0003723molecular_functionRNA binding
B0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
B0005665cellular_componentRNA polymerase II, core complex
B0005721cellular_componentpericentric heterochromatin
B0006351biological_processDNA-templated transcription
B0006366biological_processtranscription by RNA polymerase II
B0006367biological_processtranscription initiation at RNA polymerase II promoter
B0016740molecular_functiontransferase activity
B0016779molecular_functionnucleotidyltransferase activity
B0032549molecular_functionribonucleoside binding
B0034062molecular_function5'-3' RNA polymerase activity
B0046872molecular_functionmetal ion binding
B0140727biological_processsiRNA-mediated pericentric heterochromatin formation
C0000428cellular_componentDNA-directed RNA polymerase complex
C0001055molecular_functionRNA polymerase II activity
C0003677molecular_functionDNA binding
C0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
C0005665cellular_componentRNA polymerase II, core complex
C0006351biological_processDNA-templated transcription
C0046872molecular_functionmetal ion binding
C0046983molecular_functionprotein dimerization activity
C0055029cellular_componentnuclear DNA-directed RNA polymerase complex
D0000166molecular_functionnucleotide binding
D0000288biological_processnuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
D0000932cellular_componentP-body
D0001172biological_processRNA-templated transcription
D0003697molecular_functionsingle-stranded DNA binding
D0003727molecular_functionsingle-stranded RNA binding
D0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
D0003968molecular_functionRNA-dependent RNA polymerase activity
D0005634cellular_componentnucleus
D0005665cellular_componentRNA polymerase II, core complex
D0005737cellular_componentcytoplasm
D0006352biological_processDNA-templated transcription initiation
D0006366biological_processtranscription by RNA polymerase II
D0006367biological_processtranscription initiation at RNA polymerase II promoter
D0006368biological_processtranscription elongation by RNA polymerase II
D0030880cellular_componentRNA polymerase complex
D0031369molecular_functiontranslation initiation factor binding
D0034402biological_processrecruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex
D0044237biological_processcellular metabolic process
D0045948biological_processpositive regulation of translational initiation
D1990328cellular_componentRPB4-RPB7 complex
E0001054molecular_functionRNA polymerase I activity
E0001055molecular_functionRNA polymerase II activity
E0001056molecular_functionRNA polymerase III activity
E0001172biological_processRNA-templated transcription
E0003677molecular_functionDNA binding
E0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
E0003968molecular_functionRNA-dependent RNA polymerase activity
E0005634cellular_componentnucleus
E0005665cellular_componentRNA polymerase II, core complex
E0005666cellular_componentRNA polymerase III complex
E0005736cellular_componentRNA polymerase I complex
E0006351biological_processDNA-templated transcription
E0006360biological_processtranscription by RNA polymerase I
E0006361biological_processtranscription initiation at RNA polymerase I promoter
E0006362biological_processtranscription elongation by RNA polymerase I
E0006363biological_processtermination of RNA polymerase I transcription
E0006366biological_processtranscription by RNA polymerase II
E0006367biological_processtranscription initiation at RNA polymerase II promoter
E0006368biological_processtranscription elongation by RNA polymerase II
E0006383biological_processtranscription by RNA polymerase III
E0006384biological_processtranscription initiation at RNA polymerase III promoter
E0006386biological_processtermination of RNA polymerase III transcription
E0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
E0042797biological_processtRNA transcription by RNA polymerase III
E0055029cellular_componentnuclear DNA-directed RNA polymerase complex
F0000428cellular_componentDNA-directed RNA polymerase complex
F0001054molecular_functionRNA polymerase I activity
F0001055molecular_functionRNA polymerase II activity
F0001056molecular_functionRNA polymerase III activity
F0001172biological_processRNA-templated transcription
F0003677molecular_functionDNA binding
F0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
F0003968molecular_functionRNA-dependent RNA polymerase activity
F0005634cellular_componentnucleus
F0005665cellular_componentRNA polymerase II, core complex
F0005666cellular_componentRNA polymerase III complex
F0005736cellular_componentRNA polymerase I complex
F0006351biological_processDNA-templated transcription
F0006360biological_processtranscription by RNA polymerase I
F0006361biological_processtranscription initiation at RNA polymerase I promoter
F0006362biological_processtranscription elongation by RNA polymerase I
F0006363biological_processtermination of RNA polymerase I transcription
F0006366biological_processtranscription by RNA polymerase II
F0006367biological_processtranscription initiation at RNA polymerase II promoter
F0006368biological_processtranscription elongation by RNA polymerase II
F0006383biological_processtranscription by RNA polymerase III
F0006384biological_processtranscription initiation at RNA polymerase III promoter
F0006386biological_processtermination of RNA polymerase III transcription
F0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
F0042797biological_processtRNA transcription by RNA polymerase III
G0000291biological_processnuclear-transcribed mRNA catabolic process, exonucleolytic
G0000428cellular_componentDNA-directed RNA polymerase complex
G0000932cellular_componentP-body
G0003676molecular_functionnucleic acid binding
G0003697molecular_functionsingle-stranded DNA binding
G0003727molecular_functionsingle-stranded RNA binding
G0005634cellular_componentnucleus
G0005665cellular_componentRNA polymerase II, core complex
G0006351biological_processDNA-templated transcription
G0006352biological_processDNA-templated transcription initiation
G0006367biological_processtranscription initiation at RNA polymerase II promoter
G0010590biological_processregulation of septum digestion after cytokinesis
G0031369molecular_functiontranslation initiation factor binding
G0045948biological_processpositive regulation of translational initiation
G0055029cellular_componentnuclear DNA-directed RNA polymerase complex
G0060213biological_processpositive regulation of nuclear-transcribed mRNA poly(A) tail shortening
H0001054molecular_functionRNA polymerase I activity
H0001055molecular_functionRNA polymerase II activity
H0001056molecular_functionRNA polymerase III activity
H0001172biological_processRNA-templated transcription
H0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
H0003968molecular_functionRNA-dependent RNA polymerase activity
H0005634cellular_componentnucleus
H0005665cellular_componentRNA polymerase II, core complex
H0005666cellular_componentRNA polymerase III complex
H0005736cellular_componentRNA polymerase I complex
H0006351biological_processDNA-templated transcription
H0006360biological_processtranscription by RNA polymerase I
H0006361biological_processtranscription initiation at RNA polymerase I promoter
H0006362biological_processtranscription elongation by RNA polymerase I
H0006363biological_processtermination of RNA polymerase I transcription
H0006366biological_processtranscription by RNA polymerase II
H0006367biological_processtranscription initiation at RNA polymerase II promoter
H0006368biological_processtranscription elongation by RNA polymerase II
H0006383biological_processtranscription by RNA polymerase III
H0006384biological_processtranscription initiation at RNA polymerase III promoter
H0006386biological_processtermination of RNA polymerase III transcription
H0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
H0042797biological_processtRNA transcription by RNA polymerase III
I0000428cellular_componentDNA-directed RNA polymerase complex
I0001193biological_processmaintenance of transcriptional fidelity during transcription elongation by RNA polymerase II
I0003676molecular_functionnucleic acid binding
I0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
I0005634cellular_componentnucleus
I0005665cellular_componentRNA polymerase II, core complex
I0005730cellular_componentnucleolus
I0006283biological_processtranscription-coupled nucleotide-excision repair
I0006351biological_processDNA-templated transcription
I0006367biological_processtranscription initiation at RNA polymerase II promoter
I0008270molecular_functionzinc ion binding
I0046872molecular_functionmetal ion binding
J0000428cellular_componentDNA-directed RNA polymerase complex
J0001054molecular_functionRNA polymerase I activity
J0001055molecular_functionRNA polymerase II activity
J0001056molecular_functionRNA polymerase III activity
J0003677molecular_functionDNA binding
J0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
J0005665cellular_componentRNA polymerase II, core complex
J0005666cellular_componentRNA polymerase III complex
J0005736cellular_componentRNA polymerase I complex
J0006351biological_processDNA-templated transcription
J0006360biological_processtranscription by RNA polymerase I
J0006366biological_processtranscription by RNA polymerase II
J0006367biological_processtranscription initiation at RNA polymerase II promoter
J0006383biological_processtranscription by RNA polymerase III
J0008270molecular_functionzinc ion binding
J0042797biological_processtRNA transcription by RNA polymerase III
J0046872molecular_functionmetal ion binding
K0000428cellular_componentDNA-directed RNA polymerase complex
K0001055molecular_functionRNA polymerase II activity
K0001172biological_processRNA-templated transcription
K0003677molecular_functionDNA binding
K0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
K0003968molecular_functionRNA-dependent RNA polymerase activity
K0005634cellular_componentnucleus
K0005665cellular_componentRNA polymerase II, core complex
K0006351biological_processDNA-templated transcription
K0006366biological_processtranscription by RNA polymerase II
K0006367biological_processtranscription initiation at RNA polymerase II promoter
K0006368biological_processtranscription elongation by RNA polymerase II
K0006369biological_processtermination of RNA polymerase II transcription
K0046983molecular_functionprotein dimerization activity
L0001054molecular_functionRNA polymerase I activity
L0001055molecular_functionRNA polymerase II activity
L0001056molecular_functionRNA polymerase III activity
L0003677molecular_functionDNA binding
L0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
L0005665cellular_componentRNA polymerase II, core complex
L0005666cellular_componentRNA polymerase III complex
L0005736cellular_componentRNA polymerase I complex
L0006351biological_processDNA-templated transcription
L0008270molecular_functionzinc ion binding
L0046872molecular_functionmetal ion binding
a0000775cellular_componentchromosome, centromeric region
a0000781cellular_componentchromosome, telomeric region
a0000785cellular_componentchromatin
a0000786cellular_componentnucleosome
a0000939cellular_componentinner kinetochore
a0000978molecular_functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
a0000979molecular_functionRNA polymerase II core promoter sequence-specific DNA binding
a0001556biological_processoocyte maturation
a0001649biological_processosteoblast differentiation
a0001740cellular_componentBarr body
a0003677molecular_functionDNA binding
a0005515molecular_functionprotein binding
a0005576cellular_componentextracellular region
a0005634cellular_componentnucleus
a0005654cellular_componentnucleoplasm
a0005694cellular_componentchromosome
a0006334biological_processnucleosome assembly
a0006997biological_processnucleus organization
a0007283biological_processspermatogenesis
a0007286biological_processspermatid development
a0007338biological_processsingle fertilization
a0007566biological_processembryo implantation
a0008283biological_processcell population proliferation
a0008584biological_processmale gonad development
a0030307biological_processpositive regulation of cell growth
a0030527molecular_functionstructural constituent of chromatin
a0031492molecular_functionnucleosomal DNA binding
a0031508biological_processpericentric heterochromatin formation
a0031509biological_processsubtelomeric heterochromatin formation
a0032200biological_processtelomere organization
a0032991cellular_componentprotein-containing complex
a0035264biological_processmulticellular organism growth
a0042692biological_processmuscle cell differentiation
a0043229cellular_componentintracellular organelle
a0046982molecular_functionprotein heterodimerization activity
a0048477biological_processoogenesis
a0070062cellular_componentextracellular exosome
a0090230biological_processregulation of centromere complex assembly
a1902340biological_processnegative regulation of chromosome condensation
b0000781cellular_componentchromosome, telomeric region
b0000786cellular_componentnucleosome
b0003677molecular_functionDNA binding
b0003723molecular_functionRNA binding
b0005515molecular_functionprotein binding
b0005576cellular_componentextracellular region
b0005634cellular_componentnucleus
b0005654cellular_componentnucleoplasm
b0005694cellular_componentchromosome
b0006325biological_processchromatin organization
b0006334biological_processnucleosome assembly
b0016020cellular_componentmembrane
b0030527molecular_functionstructural constituent of chromatin
b0032200biological_processtelomere organization
b0032991cellular_componentprotein-containing complex
b0043505cellular_componentCENP-A containing nucleosome
b0045653biological_processnegative regulation of megakaryocyte differentiation
b0046982molecular_functionprotein heterodimerization activity
b0061644biological_processprotein localization to CENP-A containing chromatin
b0070062cellular_componentextracellular exosome
c0000786cellular_componentnucleosome
c0003677molecular_functionDNA binding
c0005515molecular_functionprotein binding
c0005634cellular_componentnucleus
c0005694cellular_componentchromosome
c0006325biological_processchromatin organization
c0008285biological_processnegative regulation of cell population proliferation
c0030527molecular_functionstructural constituent of chromatin
c0031492molecular_functionnucleosomal DNA binding
c0043229cellular_componentintracellular organelle
c0043505cellular_componentCENP-A containing nucleosome
c0046982molecular_functionprotein heterodimerization activity
c0061644biological_processprotein localization to CENP-A containing chromatin
c0070062cellular_componentextracellular exosome
c0070828biological_processheterochromatin organization
d0000786cellular_componentnucleosome
d0001530molecular_functionlipopolysaccharide binding
d0002227biological_processinnate immune response in mucosa
d0003677molecular_functionDNA binding
d0005515molecular_functionprotein binding
d0005615cellular_componentextracellular space
d0005634cellular_componentnucleus
d0005654cellular_componentnucleoplasm
d0005694cellular_componentchromosome
d0005829cellular_componentcytosol
d0005886cellular_componentplasma membrane
d0006325biological_processchromatin organization
d0006334biological_processnucleosome assembly
d0010804biological_processnegative regulation of tumor necrosis factor-mediated signaling pathway
d0019731biological_processantibacterial humoral response
d0030527molecular_functionstructural constituent of chromatin
d0031640biological_processkilling of cells of another organism
d0042742biological_processdefense response to bacterium
d0043229cellular_componentintracellular organelle
d0043505cellular_componentCENP-A containing nucleosome
d0046982molecular_functionprotein heterodimerization activity
d0050829biological_processdefense response to Gram-negative bacterium
d0050830biological_processdefense response to Gram-positive bacterium
d0061644biological_processprotein localization to CENP-A containing chromatin
d0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
e0000775cellular_componentchromosome, centromeric region
e0000781cellular_componentchromosome, telomeric region
e0000785cellular_componentchromatin
e0000786cellular_componentnucleosome
e0000939cellular_componentinner kinetochore
e0000978molecular_functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
e0000979molecular_functionRNA polymerase II core promoter sequence-specific DNA binding
e0001556biological_processoocyte maturation
e0001649biological_processosteoblast differentiation
e0001740cellular_componentBarr body
e0003677molecular_functionDNA binding
e0005515molecular_functionprotein binding
e0005576cellular_componentextracellular region
e0005634cellular_componentnucleus
e0005654cellular_componentnucleoplasm
e0005694cellular_componentchromosome
e0006334biological_processnucleosome assembly
e0006997biological_processnucleus organization
e0007283biological_processspermatogenesis
e0007286biological_processspermatid development
e0007338biological_processsingle fertilization
e0007566biological_processembryo implantation
e0008283biological_processcell population proliferation
e0008584biological_processmale gonad development
e0030307biological_processpositive regulation of cell growth
e0030527molecular_functionstructural constituent of chromatin
e0031492molecular_functionnucleosomal DNA binding
e0031508biological_processpericentric heterochromatin formation
e0031509biological_processsubtelomeric heterochromatin formation
e0032200biological_processtelomere organization
e0032991cellular_componentprotein-containing complex
e0035264biological_processmulticellular organism growth
e0042692biological_processmuscle cell differentiation
e0043229cellular_componentintracellular organelle
e0046982molecular_functionprotein heterodimerization activity
e0048477biological_processoogenesis
e0070062cellular_componentextracellular exosome
e0090230biological_processregulation of centromere complex assembly
e1902340biological_processnegative regulation of chromosome condensation
f0000781cellular_componentchromosome, telomeric region
f0000786cellular_componentnucleosome
f0003677molecular_functionDNA binding
f0003723molecular_functionRNA binding
f0005515molecular_functionprotein binding
f0005576cellular_componentextracellular region
f0005634cellular_componentnucleus
f0005654cellular_componentnucleoplasm
f0005694cellular_componentchromosome
f0006325biological_processchromatin organization
f0006334biological_processnucleosome assembly
f0016020cellular_componentmembrane
f0030527molecular_functionstructural constituent of chromatin
f0032200biological_processtelomere organization
f0032991cellular_componentprotein-containing complex
f0043505cellular_componentCENP-A containing nucleosome
f0045653biological_processnegative regulation of megakaryocyte differentiation
f0046982molecular_functionprotein heterodimerization activity
f0061644biological_processprotein localization to CENP-A containing chromatin
f0070062cellular_componentextracellular exosome
g0000786cellular_componentnucleosome
g0003677molecular_functionDNA binding
g0005515molecular_functionprotein binding
g0005634cellular_componentnucleus
g0005694cellular_componentchromosome
g0006325biological_processchromatin organization
g0008285biological_processnegative regulation of cell population proliferation
g0030527molecular_functionstructural constituent of chromatin
g0031492molecular_functionnucleosomal DNA binding
g0043229cellular_componentintracellular organelle
g0043505cellular_componentCENP-A containing nucleosome
g0046982molecular_functionprotein heterodimerization activity
g0061644biological_processprotein localization to CENP-A containing chromatin
g0070062cellular_componentextracellular exosome
g0070828biological_processheterochromatin organization
h0000786cellular_componentnucleosome
h0001530molecular_functionlipopolysaccharide binding
h0002227biological_processinnate immune response in mucosa
h0003677molecular_functionDNA binding
h0005515molecular_functionprotein binding
h0005615cellular_componentextracellular space
h0005634cellular_componentnucleus
h0005654cellular_componentnucleoplasm
h0005694cellular_componentchromosome
h0005829cellular_componentcytosol
h0005886cellular_componentplasma membrane
h0006325biological_processchromatin organization
h0006334biological_processnucleosome assembly
h0010804biological_processnegative regulation of tumor necrosis factor-mediated signaling pathway
h0019731biological_processantibacterial humoral response
h0030527molecular_functionstructural constituent of chromatin
h0031640biological_processkilling of cells of another organism
h0042742biological_processdefense response to bacterium
h0043229cellular_componentintracellular organelle
h0043505cellular_componentCENP-A containing nucleosome
h0046982molecular_functionprotein heterodimerization activity
h0050829biological_processdefense response to Gram-negative bacterium
h0050830biological_processdefense response to Gram-positive bacterium
h0061644biological_processprotein localization to CENP-A containing chromatin
h0061844biological_processantimicrobial humoral immune response mediated by antimicrobial peptide
Functional Information from PDB Data
site_idAC1
Number of Residues4
Detailsbinding site for residue ZN A 1801
ChainResidue
ACYS67
ACYS70
ACYS77
AHIS80

site_idAC2
Number of Residues4
Detailsbinding site for residue ZN A 1802
ChainResidue
ACYS107
ACYS148
AGLY167
ACYS168

site_idAC3
Number of Residues3
Detailsbinding site for residue MG A 1803
ChainResidue
AASP484
PC10
AASP482

site_idAC4
Number of Residues4
Detailsbinding site for residue ZN B 1301
ChainResidue
BCYS1163
BCYS1166
BCYS1182
BCYS1185

site_idAC5
Number of Residues4
Detailsbinding site for residue ZN C 401
ChainResidue
CCYS85
CCYS87
CCYS91
CGLU93

site_idAC6
Number of Residues6
Detailsbinding site for residue ZN I 201
ChainResidue
ICYS75
IGLU77
ICYS78
ICYS103
IASN105
ICYS106

site_idAC7
Number of Residues3
Detailsbinding site for residue ZN I 202
ChainResidue
IGLU9
ICYS10
ICYS32

site_idAC8
Number of Residues4
Detailsbinding site for residue ZN J 101
ChainResidue
JCYS7
JCYS10
JCYS44
JCYS45

site_idAC9
Number of Residues4
Detailsbinding site for residue ZN L 101
ChainResidue
LCYS33
LALA35
LCYS36
LCYS50

Functional Information from PROSITE/UniProt
site_idPS01166
Number of Residues13
DetailsRNA_POL_BETA RNA polymerases beta chain signature. GdKFASrHGQKGT
ChainResidueDetails
BGLY977-THR989

site_idPS00357
Number of Residues23
DetailsHISTONE_H2B Histone H2B signature. REIQTavRlLLpGELaKHAVSEG
ChainResidueDetails
dARG89-GLY111

site_idPS01110
Number of Residues14
DetailsRNA_POL_H_23KD RNA polymerases H / 23 Kd subunits signature. HELVPKHirLsdGE
ChainResidueDetails
EHIS146-GLU159

site_idPS00446
Number of Residues41
DetailsRNA_POL_D_30KD RNA polymerases D / 30 to 40 Kd subunits signature. NSLRRtmlaevptlAidlVeikmNtSvlaDEfIShRLGLIP
ChainResidueDetails
CASN30-PRO70

site_idPS01111
Number of Residues15
DetailsRNA_POL_K_14KD RNA polymerases K / 14 to 18 Kd subunits signature. TkYErARiLGtRAlQ
ChainResidueDetails
FTHR86-GLN100

site_idPS01030
Number of Residues27
DetailsRNA_POL_M_15KD RNA polymerases M / 15 Kd subunits signature. FClECNNMLypkedkenqrllysCrnC
ChainResidueDetails
IPHE6-CYS32

site_idPS00046
Number of Residues7
DetailsHISTONE_H2A Histone H2A signature. AGLqFPV
ChainResidueDetails
cALA21-VAL27

site_idPS01154
Number of Residues32
DetailsRNA_POL_L_13KD RNA polymerases L / 13 to 16 Kd subunits signature. FerEdHTLaNlLreeLalypdVtfvaYkveHP
ChainResidueDetails
KPHE35-PRO66

site_idPS00047
Number of Residues5
DetailsHISTONE_H4 Histone H4 signature. GAKRH
ChainResidueDetails
bGLY14-HIS18

site_idPS00322
Number of Residues7
DetailsHISTONE_H3_1 Histone H3 signature 1. KAPRKQL
ChainResidueDetails
aLYS14-LEU20

site_idPS00959
Number of Residues9
DetailsHISTONE_H3_2 Histone H3 signature 2. PFqRLVREI
ChainResidueDetails
aPRO66-ILE74

site_idPS00115
Number of Residues7
DetailsRNA_POL_II_REPEAT Eukaryotic RNA polymerase II heptapeptide repeat. YSPTSPS
ChainResidueDetails
ATYR1560-SER1566
ATYR1567-SER1573
ATYR1574-SER1580
ATYR1581-SER1587
ATYR1588-SER1594
ATYR1595-SER1601
ATYR1602-SER1608
ATYR1609-SER1615
ATYR1616-SER1622

site_idPS01112
Number of Residues10
DetailsRNA_POL_N_8KD RNA polymerases N / 8 Kd subunits signature. IIPVrCFSCG
ChainResidueDetails
JILE2-GLY11

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: N-acetylproline => ECO:0000250|UniProtKB:P23527
ChainResidueDetails
dPRO-2
hPRO-2

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: ADP-ribosyl glutamic acid => ECO:0000269|PubMed:27530147
ChainResidueDetails
dGLU-1
hGLU-1

site_idSWS_FT_FI3
Number of Residues16
DetailsMOD_RES: N6-lactoyllysine; alternate => ECO:0000269|PubMed:31645732
ChainResidueDetails
dLYS2
hLYS8
hLYS12
hLYS13
hLYS17
hLYS20
hLYS40
hLYS82
dLYS8
dLYS12
dLYS13
dLYS17
dLYS20
dLYS40
dLYS82
hLYS2

site_idSWS_FT_FI4
Number of Residues2
DetailsMOD_RES: ADP-ribosylserine => ECO:0000269|PubMed:34874266
ChainResidueDetails
dSER3
hSER3
gLYS9
gLYS95

site_idSWS_FT_FI5
Number of Residues2
DetailsMOD_RES: N6-crotonyllysine; alternate => ECO:0000269|PubMed:21925322
ChainResidueDetails
dLYS9
hLYS9
bLYS44
fLYS8
fLYS16
fLYS44

site_idSWS_FT_FI6
Number of Residues2
DetailsMOD_RES: Phosphoserine; by STK4/MST1 => ECO:0000269|PubMed:12757711
ChainResidueDetails
dSER11
hSER11
bLYS77
bLYS91
fLYS12
fLYS31
fLYS77
fLYS91

site_idSWS_FT_FI7
Number of Residues2
DetailsMOD_RES: N6-(2-hydroxyisobutyryl)lysine => ECO:0000269|PubMed:24681537
ChainResidueDetails
dLYS21
hLYS21
gLYS74
gLYS75

site_idSWS_FT_FI8
Number of Residues6
DetailsMOD_RES: N6-succinyllysine; alternate => ECO:0000269|PubMed:22389435
ChainResidueDetails
dLYS31
dLYS113
dLYS117
hLYS31
hLYS113
hLYS117

site_idSWS_FT_FI9
Number of Residues2
DetailsMOD_RES: PolyADP-ribosyl glutamic acid => ECO:0000250|UniProtKB:Q64475
ChainResidueDetails
dGLU32
hGLU32
cLYS125
gLYS118
gLYS119
gLYS125

site_idSWS_FT_FI10
Number of Residues2
DetailsMOD_RES: Phosphoserine; by AMPK => ECO:0000250|UniProtKB:Q64475
ChainResidueDetails
dSER33
hSER33

site_idSWS_FT_FI11
Number of Residues4
DetailsMOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:16627869
ChainResidueDetails
dLYS43
dLYS105
hLYS43
hLYS105

site_idSWS_FT_FI12
Number of Residues2
DetailsMOD_RES: N6-(2-hydroxyisobutyryl)lysine; alternate => ECO:0000269|PubMed:24681537
ChainResidueDetails
dLYS54
hLYS54
gLYS119

site_idSWS_FT_FI13
Number of Residues2
DetailsMOD_RES: Dimethylated arginine => ECO:0000250|UniProtKB:Q96A08
ChainResidueDetails
dARG76
hARG76
eLYS18
eLYS64

site_idSWS_FT_FI14
Number of Residues4
DetailsMOD_RES: Omega-N-methylarginine => ECO:0000250|UniProtKB:Q96A08
ChainResidueDetails
dARG83
dARG89
hARG83
hARG89

site_idSWS_FT_FI15
Number of Residues2
DetailsMOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q00729
ChainResidueDetails
dTHR112
hTHR112
fLYS91

site_idSWS_FT_FI16
Number of Residues2
DetailsCARBOHYD: O-linked (GlcNAc) serine => ECO:0000250|UniProtKB:P62807
ChainResidueDetails
dSER109
hSER109
bLYS79
fLYS20
fLYS59
fLYS79

site_idSWS_FT_FI17
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0000250|UniProtKB:P58876
ChainResidueDetails
dLYS2
hLYS2

site_idSWS_FT_FI18
Number of Residues4
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000269|PubMed:16307923, ECO:0000269|PubMed:16627869, ECO:0000269|PubMed:16713563
ChainResidueDetails
aSER31
dLYS117
hLYS117

site_idSWS_FT_FI19
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0000250|UniProtKB:Q5QNW6
ChainResidueDetails
dLYS17
hLYS17

site_idSWS_FT_FI20
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000269|PubMed:21726816
ChainResidueDetails
dLYS31
hLYS31

site_idSWS_FT_FI21
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0000269|PubMed:20850016
ChainResidueDetails
aSER57
eSER57

site_idSWS_FT_FI22
Number of Residues2
DetailsMOD_RES: N6-succinyllysine; alternate => ECO:0000269|PubMed:22389435, ECO:0000269|PubMed:29211711
ChainResidueDetails
aLYS79
eLYS79

site_idSWS_FT_FI23
Number of Residues2
DetailsMOD_RES: Phosphothreonine => ECO:0000269|PubMed:20850016
ChainResidueDetails
aTHR80
eTHR80

site_idSWS_FT_FI24
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569
ChainResidueDetails
aSER86
eSER86

site_idSWS_FT_FI25
Number of Residues2
DetailsMOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q71DI3
ChainResidueDetails
aTHR107
eTHR107

site_idSWS_FT_FI26
Number of Residues2
DetailsMOD_RES: N6-glutaryllysine; alternate => ECO:0000269|PubMed:31542297
ChainResidueDetails
aLYS115
eLYS115

site_idSWS_FT_FI27
Number of Residues2
DetailsMOD_RES: N6-succinyllysine; alternate => ECO:0000269|PubMed:22389435, ECO:0000269|PubMed:27436229
ChainResidueDetails
aLYS122
eLYS122

site_idSWS_FT_FI28
Number of Residues2
DetailsLIPID: N6-decanoyllysine => ECO:0000269|PubMed:35939806
ChainResidueDetails
aLYS18
eLYS18

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon