5FIU
Binding and structural studies of a 5,5-difluoromethyl adenosine nucleoside with the fluorinase enzyme
Summary for 5FIU
Entry DOI | 10.2210/pdb5fiu/pdb |
Descriptor | 5'-FLUORO-5'-DEOXY-ADENOSINE SYNTHASE, 5,5-DIFLUOROMETHYL ADENOSINE, L(+)-TARTARIC ACID, ... (4 entities in total) |
Functional Keywords | transferase, fluorinase, difluoromethyl, isothermal titration calorimetry |
Biological source | STREPTOMYCES CATTLEYA |
Total number of polymer chains | 3 |
Total formula weight | 98516.40 |
Authors | Thompson, S.,McMahon, S.A.,Naismith, J.H.,O'Hagan, D. (deposition date: 2015-10-02, release date: 2015-12-23, Last modification date: 2024-01-10) |
Primary citation | Thompson, S.,Mcmahon, S.A.,Naismith, J.H.,O'Hagan, D. Exploration of a Potential Difluoromethyl-Nucleoside Substrate with the Fluorinase Enzyme. Bioorg.Chem., 64:37-, 2015 Cited by PubMed: 26642178DOI: 10.1016/J.BIOORG.2015.11.003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.84 Å) |
Structure validation
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