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6NUO
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BU of 6nuo by Molmil
Modified tRNA(Pro) bound to Thermus thermophilus 70S (cognate)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Hoffer, E.D, Subaramanian, S, Hong, S, Maehigashi, T, Dunham, C.M.
登録日2019-02-01
公開日2020-10-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
6NWY
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BU of 6nwy by Molmil
Modified tRNA(Pro) bound to Thermus thermophilus 70S (near-cognate)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Hoffer, E.D, Subaramanian, S, Hong, S, Maehigashi, T, Dunham, C.M.
登録日2019-02-07
公開日2020-10-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
6O3M
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BU of 6o3m by Molmil
Unmodified tRNA(Pro) bound to Thermus thermophilus 70S (cognate)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Hoffer, E.D, Subaramanian, S, Hong, S, Maehigashi, T, Dunham, C.M.
登録日2019-02-26
公開日2020-10-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.97 Å)
主引用文献Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
6NSH
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BU of 6nsh by Molmil
Modified ASL proline bound to Thermus thermophilus 70S (near-cognate)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Hoffer, E.D, Maehigashi, T, Subaramanian, S, Hong, S, Dunham, C.M.
登録日2019-01-24
公開日2020-10-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.397 Å)
主引用文献Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
6O9K
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BU of 6o9k by Molmil
70S initiation complex
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Frank, J, Gonzalez Jr, R.L, kaledhonkar, S, Fu, Z, Caban, K, Li, W, Chen, B, Sun, M.
登録日2019-03-14
公開日2019-05-29
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Late steps in bacterial translation initiation visualized using time-resolved cryo-EM.
Nature, 570, 2019
6OKK
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BU of 6okk by Molmil
Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, small subunit
分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Wong, W, Scheres, S.H.W.
登録日2019-04-13
公開日2019-05-22
最終更新日2020-01-08
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.
Elife, 3, 2014
6O97
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BU of 6o97 by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with propylamycin and bound to mRNA and A-, P-, and E-site tRNAs at 2.75A resolution
分子名称: (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxyc yclohexyl 2-amino-2,4-dideoxy-4-propyl-alpha-D-glucopyranoside, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
著者Matsushita, T, Sati, G.C, Kondasinghe, N, Pirrone, M.G, Kato, T, Waduge, P, Kumar, H.S, Sanchon, A.C, Dobosz-Bartoszek, M, Shcherbakov, D, Juhas, M, Hobbie, S.N, Schrepfer, T, Chow, C.S, Polikanov, Y.S, Schacht, J, Vasella, A, Bottger, E.C, Crich, D.
登録日2019-03-13
公開日2019-04-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Design, Multigram Synthesis, and in Vitro and in Vivo Evaluation of Propylamycin: A Semisynthetic 4,5-Deoxystreptamine Class Aminoglycoside for the Treatment of Drug-Resistant Enterobacteriaceae and Other Gram-Negative Pathogens.
J. Am. Chem. Soc., 141, 2019
6OLI
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BU of 6oli by Molmil
Structure of human ribosome nascent chain complex selectively stalled by a drug-like small molecule (USO1-RNC)
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-16
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6ORL
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BU of 6orl by Molmil
RF1 pre-accommodated 70S complex at 24 ms
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J.
登録日2019-04-30
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
6O9J
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BU of 6o9j by Molmil
70S Elongation Competent Ribosome
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Frank, J, Gonzalez Jr, R.L, Kaledhonkar, S, Fu, Z, Caban, K, Li, W, Chen, B, Sun, M.
登録日2019-03-14
公開日2019-05-29
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Late steps in bacterial translation initiation visualized using time-resolved cryo-EM.
Nature, 570, 2019
6OFX
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BU of 6ofx by Molmil
Non-rotated ribosome (Structure I)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Svidritskiy, E, Demo, G, Loveland, A.B, Xu, C, Korostelev, A.A.
登録日2019-04-01
公開日2019-09-25
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Extensive ribosome and RF2 rearrangements during translation termination.
Elife, 8, 2019
6OM0
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BU of 6om0 by Molmil
Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAs
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-17
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OT3
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BU of 6ot3 by Molmil
RF2 accommodated state bound Release complex 70S at 24 ms
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J.
登録日2019-05-02
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
6OST
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BU of 6ost by Molmil
RF2 pre-accommodated state bound Release complex 70S at 24ms
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J.
登録日2019-05-02
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
6O90
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BU of 6o90 by Molmil
Cryo-EM image reconstruction of the 70S Ribosome Enterococcus faecalis Class05
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Jogl, G, Khayat, R.
登録日2019-03-12
公開日2020-09-23
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.49 Å)
主引用文献Cryo-electron microscopy structure of the 70S ribosome from Enterococcus faecalis.
Sci Rep, 10, 2020
6OG7
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BU of 6og7 by Molmil
70S termination complex with RF2 bound to the UGA codon. Non-rotated ribosome with RF2 bound (Structure II)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Svidritskiy, E, Demo, G, Loveland, A.B, Xu, C, Korostelev, A.A.
登録日2019-04-01
公開日2019-09-25
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Extensive ribosome and RF2 rearrangements during translation termination.
Elife, 8, 2019
6OTR
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BU of 6otr by Molmil
Dimeric E.coli YoeB bound to Thermus thermophilus 70S post-cleavage (AAU)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Pavelich, I.P, Hoffer, E.D, Maehigashi, T, Dunham, C.M.
登録日2019-05-03
公開日2019-08-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.12 Å)
主引用文献Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability.
Nucleic Acids Res., 47, 2019
6O7K
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BU of 6o7k by Molmil
30S initiation complex
分子名称: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Frank, J, Gonzalez Jr, R.L, kaledhonkar, S, Fu, Z, Caban, K, Li, W, Chen, B, Sun, M.
登録日2019-03-08
公開日2019-05-29
最終更新日2020-01-29
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Late steps in bacterial translation initiation visualized using time-resolved cryo-EM.
Nature, 570, 2019
6O8Z
DownloadVisualize
BU of 6o8z by Molmil
Cryo-EM image reconstruction of the 70S Ribosome Enterococcus faecalis Class04
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Jogl, G, Khayat, R.
登録日2019-03-12
公開日2020-09-16
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.49 Å)
主引用文献Cryo-electron microscopy structure of the 70S ribosome from Enterococcus faecalis.
Sci Rep, 10, 2020
6OLE
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BU of 6ole by Molmil
Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-16
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6ORD
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BU of 6ord by Molmil
Crystal structure of tRNA^ Ala(GGC) U32-A38 bound to cognate 70S A site
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Nguyen, H.A, Sunita, S, Dunham, C.M.
登録日2019-04-30
公開日2020-06-24
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Disruption of evolutionarily correlated tRNA elements impairs accurate decoding.
Proc.Natl.Acad.Sci.USA, 117, 2020
6O8X
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BU of 6o8x by Molmil
Cryo-EM image reconstruction of the 70S Ribosome Enterococcus faecalis Class02
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Jogl, G, Khayat, R.
登録日2019-03-12
公開日2020-09-23
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.68 Å)
主引用文献Cryo-electron microscopy structure of the 70S ribosome from Enterococcus faecalis.
Sci Rep, 10, 2020
6OLF
DownloadVisualize
BU of 6olf by Molmil
Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-16
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OPE
DownloadVisualize
BU of 6ope by Molmil
Crystal structure of tRNA^ Ala(GGC) U32-A38 bound to near-cognate 70S A site
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Nguyen, H.A, Sunita, S, Dunham, C.M.
登録日2019-04-24
公開日2020-06-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Disruption of evolutionarily correlated tRNA elements impairs accurate decoding.
Proc.Natl.Acad.Sci.USA, 117, 2020
6OF6
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BU of 6of6 by Molmil
Crystal structure of tRNA^ Ala(GGC) bound to cognate 70S A-site
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Nguyen, H.A, Sunita, S, Dunham, C.M.
登録日2019-03-28
公開日2020-06-24
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Disruption of evolutionarily correlated tRNA elements impairs accurate decoding.
Proc.Natl.Acad.Sci.USA, 117, 2020

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件を2024-08-07に公開中

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