PDB: 13258 件ウェブページステータス検索Chemie searchBIRD

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8E4H	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGAGGAAGTGGG) 分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*AP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*TP*CP*TP*TP*AP*T)-3'), Transcription factor PU.1 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-08-18 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.39 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8E3K	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGAAGTGGG) 分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-08-17 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8E5Y	Human PU.1 ETS-Domain Bound to d(AATAAGCGGAAGTGGG) Acetate Free at pH 5.4 分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-08-22 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EE9	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAAAGGAATGGGG) 分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*AP*AP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*TP*TP*TP*TP*AP*T)-3'), Transcription factor PU.1 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-09-06 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.22 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
5XV8	Solution structure of the complex between UVSSA acidic region and TFIIH p62 PH domain 分子名称: General transcription factor IIH subunit 1, UV-stimulated scaffold protein A 著者 Okuda, M, Nishimura, Y. 登録日 2017-06-27 公開日 2017-11-08 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Common TFIIH recruitment mechanism in global genome and transcription-coupled repair subpathways Nucleic Acids Res., 45, 2017
8EBH	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGAATGGGG) 分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), Transcription factor PU.1 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-08-31 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
1WPA	1.5 Angstrom crystal structure of human occludin fragment 413-522 分子名称: Occludin 著者 Li, Y, Lavie, A, Fanning, A.S, Anderson, J.M. 登録日 2004-09-01 公開日 2005-09-06 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure of the conserved cytoplasmic C-terminal domain of occludin: identification of the ZO-1 binding surface. J.Mol.Biol., 352, 2005
8EDG	Cryo-EM structure of the Hermes transposase bound to two left-ends of its DNA transposon 分子名称: DNA (46-MER), DNA (5'-D(*GP*CP*GP*TP*GP*AP*A)-3'), DNA (55-MER), ... 著者 Lannes, L, Dyda, F. 登録日 2022-09-04 公開日 2023-08-02 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (4.64 Å) 主引用文献 Zinc-finger BED domains drive the formation of the active Hermes transpososome by asymmetric DNA binding. Nat Commun, 14, 2023
8DSM	Human NAMPT in complex with inhibitor ZN-4-3 分子名称: (3S)-N-[(1-benzothiophen-5-yl)methyl]-1-[6-(4-{2-[(2E)-3-(pyridin-3-yl)prop-2-enamido]ethyl}phenyl)thieno[2,3-d]pyrimidin-4-yl]piperidine-3-carboxamide, CHLORIDE ION, GLYCEROL, ... 著者 Ratia, K, Xiong, R, Shen, Z, Thatcher, G.R. 登録日 2022-07-22 公開日 2023-08-02 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 A structural mechanism for positive allosteric modulation of nicotinamide phosphoribosyltransferase to elevate cellular NAD+ To Be Published
5X6U	Crystal structure of human heteropentameric complex 分子名称: Ragulator complex protein LAMTOR1, Ragulator complex protein LAMTOR2, Ragulator complex protein LAMTOR3, ... 著者 Yonehara, R, Nada, S, Nakai, T, Nakai, M, Kitamura, A, Ogawa, A, Nakatsumi, H, Nakayama, K.I, Li, S, Standley, D.M, Yamashita, E, Nakagawa, A, Okada, M. 登録日 2017-02-23 公開日 2017-12-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for the assembly of the Ragulator-Rag GTPase complex. Nat Commun, 8, 2017
8E67	ETV6 H396Y variant bound to DNA containing the sequence GGAT 分子名称: Complementary 15 bp strand, GGAT-containing 15 bp DNA, Transcription factor ETV6 著者 Scheu, K, Chan, A.C, Murphy, M.E, McIntosh, L.P. 登録日 2022-08-22 公開日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The functional role of histidine within the ETV6 ETS domain to be published
8E66	ETV6 H396Y variant bound to DNA containing the sequence GGAA 分子名称: CACODYLATE ION, Complementary 15 bp strand, GGAA-containing 15 bp DNA, ... 著者 Scheu, K, Chan, A.C, Murphy, M.E, McIntosh, L.P. 登録日 2022-08-22 公開日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 The functional role of histidine within the ETV6 ETS domain to be published
2X6U	Crystal structure of human TBX5 in the DNA-free form 分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, MAGNESIUM ION, T-BOX TRANSCRIPTION FACTOR TBX5 著者 Stirnimann, C.U, Mueller, C.W. 登録日 2010-02-22 公開日 2010-04-28 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural Basis of Tbx5-DNA Recognition: The T-Box Domain in its DNA-Bound and -Unbound Form. J.Mol.Biol., 400, 2010
8DPU	The crystal structure of the IL-11 signalling complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-11, ... 著者 Metcalfe, R.D, Aizel, K, Griffin, M.D.W. 登録日 2022-07-17 公開日 2023-11-29 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (3.78 Å) 主引用文献 Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant. Nat Commun, 14, 2023
8DPV	The crystal structure of Interleukin-11, W147A mutant 分子名称: CHLORIDE ION, Interleukin-11, SULFATE ION 著者 Metcalfe, R.D, Griffin, M.D.W. 登録日 2022-07-17 公開日 2023-11-29 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant. Nat Commun, 14, 2023
2WHB	Truncation and Optimisation of Peptide Inhibitors of CDK2, Cyclin A Through Structure Guided Design 分子名称: ARG-ARG-L3O-PFF, CELL DIVISION PROTEIN KINASE 2, CYCLIN-A2 著者 Kontopidis, G, Andrews, M.J, McInnes, C, Plater, A, Innes, L, Renachowski, S, Cowan, A, Fischer, P.M. 登録日 2009-05-03 公開日 2009-06-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Truncation and optimisation of peptide inhibitors of cyclin-dependent kinase 2-cyclin a through structure-guided design. Chemmedchem, 4, 2009
8DPS	The structure of the interleukin 11 signalling complex, truncated gp130 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-11, ... 著者 Metcalfe, R.D, Hanssen, E, Griffin, M.D.W. 登録日 2022-07-17 公開日 2023-11-29 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.47 Å) 主引用文献 Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant. Nat Commun, 14, 2023
8DPT	The structure of the IL-11 signalling complex, with full-length extracellular gp130 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-11, ... 著者 Metcalfe, R.D, Hanssen, E, Griffin, M.D.W. 登録日 2022-07-17 公開日 2023-11-29 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant. Nat Commun, 14, 2023
8DPW	The structure of Interleukin-11 Mutein 分子名称: Interleukin-11, SULFATE ION 著者 Metcalfe, R.D, Griffin, M.D.W. 登録日 2022-07-17 公開日 2023-11-29 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant. Nat Commun, 14, 2023
2WMA	Structural and thermodynamic consequences of cyclization of peptide ligands for the recruitment site of cyclin A 分子名称: CELL DIVISION PROTEIN KINASE 2, CYCLIC RKLFN-NH2, CYCLIN-A2 著者 Robertson, G.F, Endicott, J.A, Noble, M.E.M, McDonnell, J.M. 登録日 2009-06-30 公開日 2010-09-01 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural and Thermodynamic Consequences of Cyclization of Peptide Ligands for the Recruitment Site of Cyclin A To be Published
1CYN	CYCLOPHILIN B COMPLEXED WITH [D-(CHOLINYLESTER)SER8]-CYCLOSPORIN 分子名称: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE B 著者 Mikol, V, Kallen, J, Walkinshaw, M.D. 登録日 1995-05-22 公開日 1996-01-29 最終更新日 2018-09-12 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 X-Ray Structure of a Cyclophilin B/Cyclosporin Complex: Comparison with Cyclophilin a and Delineation of its Calcineurin-Binding Domain. Proc.Natl.Acad.Sci.USA, 91, 1994
6B8J	Co-structure of human glycogen synthase kinase beta with a selective (5-imidazol-2-yl-4-phenylpyrimidin-2-yl)[2-(2-pyridylamino)ethyl]amine inhibitor 分子名称: CHIR99021, GLYCEROL, Glycogen synthase kinase-3 beta, ... 著者 Bussiere, D.E. 登録日 2017-10-08 公開日 2017-11-08 実験手法 X-RAY DIFFRACTION (2.595 Å) 主引用文献 Synthesis, Binding Mode, and Antihyperglycemic Activity of Potent and Selective (5-Imidazol-2-yl-4-phenylpyrimidin-2-yl)[2-(2-pyridylamino)ethyl]amine Inhibitors of Glycogen Synthase Kinase 3. J. Med. Chem., 60, 2017
1WJE	SOLUTION STRUCTURE OF H12C MUTANT OF THE N-TERMINAL ZN BINDING DOMAIN OF HIV-1 INTEGRASE COMPLEXED TO CADMIUM, NMR, MINIMIZED AVERAGE STRUCTURE 分子名称: CADMIUM ION, HIV-1 INTEGRASE 著者 Cai, M, Gronenborn, A.M, Clore, G.M. 登録日 1998-06-11 公開日 1998-12-16 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution structure of the His12 --> Cys mutant of the N-terminal zinc binding domain of HIV-1 integrase complexed to cadmium. Protein Sci., 7, 1998
1WWX	Solution structure of the ETS-domain of the Ets domain transcription factor 分子名称: E74-like factor 5 ESE-2b 著者 Goroncy, A, Kigawa, T, Koshiba, S, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-01-18 公開日 2005-07-18 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the ETS-domain of the Ets domain transcription factor To be Published
5Y38	Crystal structure of C7orf59-HBXIP complex 分子名称: Ragulator complex protein LAMTOR4, Ragulator complex protein LAMTOR5, SULFATE ION 著者 Zhang, T, Ding, J. 登録日 2017-07-28 公開日 2017-12-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1 Nat Commun, 8, 2017

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