PDB: 46984 件ウェブページステータス検索Chemie searchBIRD

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8W8Q	Cryo-EM structure of the GPR101-Gs complex 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Sun, J.P, Gao, N, Yu, X, Wang, G.P, Yang, F, Wang, J.Y, Yang, Z, Guan, Y. 登録日 2023-09-04 公開日 2024-01-03 最終更新日 2024-04-10 実験手法 ELECTRON MICROSCOPY (2.89 Å) 主引用文献 Structure of GPR101-Gs enables identification of ligands with rejuvenating potential. Nat.Chem.Biol., 20, 2024
8S1P	YlmH bound to PtRNA-50S 分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... 著者 Paternoga, H, Dimitrova-Paternoga, L, Wilson, D.N. 登録日 2024-02-15 公開日 2024-06-12 実験手法 ELECTRON MICROSCOPY (1.96 Å) 主引用文献 A role for the S4-domain containing protein YlmH in ribosome-associated quality control in Bacillus subtilis. Nucleic Acids Res., 2024
8W8S	Cryo-EM structure of the AA14-bound GPR101 complex 分子名称: 1-(4-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]thiourea, Probable G-protein coupled receptor 101 著者 Sun, J.P, Yu, X, Gao, N, Yang, F, Wang, J.Y, Yang, Z, Guan, Y, Wang, G.P. 登録日 2023-09-04 公開日 2024-01-03 最終更新日 2024-04-10 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structure of GPR101-Gs enables identification of ligands with rejuvenating potential. Nat.Chem.Biol., 20, 2024
7LTA	Galectin-1 in complex with Trehalose 分子名称: DIMETHYL SULFOXIDE, Galectin-1, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose 著者 Grimm, C, Bechold, J, Seibel, J. 登録日 2021-02-19 公開日 2022-02-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Galectin-1 in complex with Trehalose To Be Published
8R8M	70S Escherichia coli ribosome with Paenilamicin B2 bound with hybrid A/P- and hybrid P/E-tRNA. 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S16, ... 著者 Koller, T.O, Wilson, D.N. 登録日 2023-11-29 公開日 2024-07-24 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Paenilamicins from the honey bee pathogen Paenibacillus larvae are context-specific translocation inhibitors of protein synthesis. Biorxiv, 2024
8R6C	70S Escherichia coli ribosome with Paenilamicin B2 bound with A- and P-site tRNA. 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S16, ... 著者 Koller, T.O, Wilson, D.N. 登録日 2023-11-22 公開日 2024-07-24 実験手法 ELECTRON MICROSCOPY (2.2 Å) 主引用文献 Paenilamicins from the honey bee pathogen Paenibacillus larvae are context-specific translocation inhibitors of protein synthesis. Biorxiv, 2024
7UAV	Structure of Clostridium botulinum prophage Tad1 in apo state 分子名称: ABC transporter ATPase 著者 Lu, A, Leavitt, A, Yirmiya, E, Amitai, G, Garb, J, Morehouse, B.R, Hobbs, S.J, Sorek, R, Kranzusch, P.J. 登録日 2022-03-14 公開日 2022-10-05 最終更新日 2022-11-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Viruses inhibit TIR gcADPR signalling to overcome bacterial defence. Nature, 611, 2022
6L49	H3-CA-H3 tri-nucleosome with the 22 base-pair linker DNA 分子名称: DNA (485-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... 著者 Takizawa, Y, Ho, C.-H, Tachiwana, H, Matsunami, H, Ohi, M, Wolf, M, Kurumizaka, H. 登録日 2019-10-16 公開日 2019-12-04 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (18.9 Å) 主引用文献 Cryo-EM Structures of Centromeric Tri-nucleosomes Containing a Central CENP-A Nucleosome. Structure, 28, 2020
7MD7	Crystal structure of the Thermus thermophilus 70S ribosome in complex with triphenylphosphonium analog of chloramphenicol CAM-C4-TPP and protein Y (YfiA) at 2.80A resolution 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... 著者 Chen, C.-W, Pavlova, J.A, Lukianov, D.A, Tereshchenkov, A.G, Makarov, G.I, Khairullina, Z.Z, Tashlitsky, V.N, Paleskava, A, Konevega, A.L, Bogdanov, A.A, Osterman, I.A, Sumbatyan, N.V, Polikanov, Y.S. 登録日 2021-04-03 公開日 2021-04-21 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Binding and Action of Triphenylphosphonium Analog of Chloramphenicol upon the Bacterial Ribosome. Antibiotics, 10, 2021
8SIY	Origin Recognition Complex Associated (ORCA) protein bound to H4K20me3-nucleosome 分子名称: Histone H2A, Histone H2B, Histone H3.2, ... 著者 Bleichert, F, Ekundayo, B.E. 登録日 2023-04-17 公開日 2023-08-02 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 A dual role for the chromatin reader ORCA/LRWD1 in targeting the origin recognition complex to chromatin. Embo J., 42, 2023
7UXH	cryo-EM structure of the mTORC1-TFEB-Rag-Ragulator complex 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Cui, Z, Hurley, J. 登録日 2022-05-05 公開日 2022-11-30 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex. Nature, 614, 2023
7UXC	cryo-EM structure of the mTORC1-TFEB-Rag-Ragulator complex with symmetry expansion 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Cui, Z, Hurley, J. 登録日 2022-05-05 公開日 2022-11-30 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex. Nature, 614, 2023
7MSC	Mtb 70SIC in complex with MtbEttA at Pre_R0 state 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Cui, Z, Zhang, J. 登録日 2021-05-11 公開日 2022-02-02 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.97 Å) 主引用文献 Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis. Nat Commun, 13, 2022
7MT7	Mtb 70S with P and E site tRNAs 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Cui, Z, Zhang, J. 登録日 2021-05-13 公開日 2022-02-02 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.71 Å) 主引用文献 Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis. Nat Commun, 13, 2022
8UD8	Crystal structure of the A2503-C2,C8-dimethylated Thermus thermophilus 70S ribosome in complex with cresomycin, mRNA, deacylated A-site tRNAphe, aminoacylated P-site fMet-tRNAmet, and deacylated E-site tRNAphe at 2.70A resolution 分子名称: (4S,5aS,8S,8aR)-4-(2-methylpropyl)-N-[(1R,5Z,7R,8R,9R,10R,11S,12R)-10,11,12-trihydroxy-7-methyl-13-oxa-2-thiabicyclo[7.3.1]tridec-5-en-8-yl]octahydro-2H-oxepino[2,3-c]pyrrole-8-carboxamide (non-preferred name), 16S Ribosomal RNA, 23S Ribosomal RNA, ... 著者 Aleksandrova, E.V, Syroegin, E.A, Wu, K.J.Y, Tresco, B.I.C, Ramkissoon, A, See, D.N.Y, Liow, P, Dittemore, G.A, Yu, M, Testolin, G, Mitcheltree, M.J, Liu, R.Y, Svetlov, M.S, Myers, A.G, Polikanov, Y.S. 登録日 2023-09-28 公開日 2024-02-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 An antibiotic preorganized for ribosomal binding overcomes antimicrobial resistance. Science, 383, 2024
8XMC	Post-translocated Pol IV transcription elongation complex 分子名称: DNA-directed RNA polymerase IV subunit 1, DNA-directed RNA polymerase IV subunit 7, DNA-directed RNA polymerases II and IV subunit 5A, ... 著者 Huang, K, Fang, C.L, Zhang, Y. 登録日 2023-12-27 公開日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Transcription of the Plant RNA polymerase IV is prone to backtracking To Be Published
8XMB	NTP-bound Pol IV transcription elongation complex 分子名称: DNA-directed RNA polymerase IV subunit 1, DNA-directed RNA polymerase IV subunit 7, DNA-directed RNA polymerases II and IV subunit 5A, ... 著者 Huang, K, Fang, C.L, Zhang, Y. 登録日 2023-12-27 公開日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Transcription of the Plant RNA polymerase IV is prone to backtracking To Be Published
7U2J	Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Gly-NH-tRNAgly, peptidyl P-site fMAC-NH-tRNAmet, deacylated E-site tRNAgly, and chloramphenicol at 2.55A resolution 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Syroegin, E.A, Aleksandrova, E.V, Polikanov, Y.S. 登録日 2022-02-24 公開日 2022-07-13 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural basis for the inability of chloramphenicol to inhibit peptide bond formation in the presence of A-site glycine. Nucleic Acids Res., 50, 2022
8XMD	Pre-translocated Pol IV transcription elongation complex 分子名称: DNA-directed RNA polymerase IV subunit 1, DNA-directed RNA polymerase IV subunit 7, DNA-directed RNA polymerases II and IV subunit 5A, ... 著者 Huang, K, Fang, C.L, Zhang, Y. 登録日 2023-12-27 公開日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Transcription of the Plant RNA polymerase IV is prone to backtracking To Be Published
8PV2	Chaetomium thermophilum pre-60S State 10 - pre-5S rotation with Ytm1-Erb1 分子名称: 26S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. 登録日 2023-07-17 公開日 2023-11-15 最終更新日 2023-12-20 実験手法 ELECTRON MICROSCOPY (2.63 Å) 主引用文献 Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation. Embo Rep., 24, 2023
8WIC	Cryo- EM structure of Mycobacterium smegmatis 50S ribosomal subunit (body 1) of 70S ribosome, E- tRNA and RafH. 分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... 著者 Kumar, N, Sharma, S, Kaushal, P.S. 登録日 2023-09-24 公開日 2024-02-28 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH. Nat Commun, 15, 2024
8WI8	Cryo- EM structure of Mycobacterium smegmatis 50S ribosomal subunit (body 1) of 70S ribosome, bS1 and RafH. 分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... 著者 Kumar, N, Sharma, S, Kaushal, P.S. 登録日 2023-09-24 公開日 2024-02-28 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH. Nat Commun, 15, 2024
8VY8	Recombinant alpha bungarotoxin complexed with HAP peptide 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Alpha-bungarotoxin isoform V31, HAP peptide 著者 Xu, J, Lei, X, Chen, L. 登録日 2024-02-07 公開日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of recombinant alpha bungarotoxin complexed with HAP peptide at 2.4 Angstroms resolution. To Be Published
8PV3	Chaetomium thermophilum pre-60S State 9 - pre-5S rotation - immature H68/H69 - composite structure 分子名称: 26S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. 登録日 2023-07-17 公開日 2023-11-15 最終更新日 2023-12-20 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation. Embo Rep., 24, 2023
7U2H	Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Gly-NH-tRNAgly, aminoacylated P-site fMet-NH-tRNAmet, and deacylated E-site tRNAgly at 2.55A resolution 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Syroegin, E.A, Aleksandrova, E.V, Polikanov, Y.S. 登録日 2022-02-24 公開日 2022-07-13 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural basis for the inability of chloramphenicol to inhibit peptide bond formation in the presence of A-site glycine. Nucleic Acids Res., 50, 2022

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