7UXC
cryo-EM structure of the mTORC1-TFEB-Rag-Ragulator complex with symmetry expansion
Summary for 7UXC
| Entry DOI | 10.2210/pdb7uxc/pdb |
| EMDB information | 26852 26857 |
| Descriptor | Serine/threonine-protein kinase mTOR, Ragulator complex protein LAMTOR5, Transcription factor EB, ... (15 entities in total) |
| Functional Keywords | mtorc1, tfeb, lysosome biogenesis, autophagy, signaling protein |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 18 |
| Total formula weight | 822322.29 |
| Authors | Cui, Z.,Hurley, J. (deposition date: 2022-05-05, release date: 2022-11-30, Last modification date: 2023-03-01) |
| Primary citation | Cui, Z.,Napolitano, G.,de Araujo, M.E.G.,Esposito, A.,Monfregola, J.,Huber, L.A.,Ballabio, A.,Hurley, J.H. Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex. Nature, 614:572-579, 2023 Cited by PubMed: 36697823DOI: 10.1038/s41586-022-05652-7 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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