PDB: 35140 件ウェブページステータス検索Chemie searchBIRD

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4Y88	Crystal structure of the N-terminal domain of CEACAM8 分子名称: 1,3-PROPANDIOL, CHLORIDE ION, Carcinoembryonic antigen-related cell adhesion molecule 8, ... 著者 Bonsor, D.A, Sundberg, E.J. 登録日 2015-02-16 公開日 2015-10-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Diverse oligomeric states of CEACAM IgV domains. Proc.Natl.Acad.Sci.USA, 112, 2015
6CAH	NMR-based structure of the FHA-2 domain from Mycobacterium tuberculosis ABC transporter Rv1747 分子名称: ABC transporter ATP-binding/permease protein Rv1747 著者 Heinkel, F, Okon, M, Gsponer, J, McIntosh, L.P. 登録日 2018-01-30 公開日 2018-06-20 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Biophysical Characterization of the Tandem FHA Domain Regulatory Module from the Mycobacterium tuberculosis ABC Transporter Rv1747. Structure, 26, 2018
1OW6	Paxillin LD4 motif bound to the Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase 分子名称: Focal adhesion kinase 1, Paxillin 著者 Hoellerer, M.K, Noble, M.E.M, Labesse, G, Campbell, I.D, Werner, J.M, Arold, S.T. 登録日 2003-03-28 公開日 2003-10-21 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Molecular Recognition of Paxillin LD motifs by the Focal Adhesion Targeting Domain Structure, 11, 2003
6T7D	Structure of human Sox11 transcription factor in complex with a nucleosome 分子名称: DNA (151-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... 著者 Dodonova, S.O, Zhu, F, Dienemann, C, Taipale, J, Cramer, P. 登録日 2019-10-21 公開日 2020-04-29 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function. Nature, 580, 2020
4YPA	ASH1L SET domain Q2265A mutant in complex with S-adenosyl methionine (SAM) 分子名称: Histone-lysine N-methyltransferase ASH1L, S-ADENOSYLMETHIONINE, ZINC ION 著者 Rogawski, D.S, Ndoj, J, Cho, H.J, Maillard, I, Grembecka, J, Cierpicki, T. 登録日 2015-03-12 公開日 2015-09-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Two Loops Undergoing Concerted Dynamics Regulate the Activity of the ASH1L Histone Methyltransferase. Biochemistry, 54, 2015
1OVE	The structure of p38 alpha in complex with a dihydroquinolinone 分子名称: 1-(2,6-DICHLOROPHENYL)-5-(2,4-DIFLUOROPHENYL)-7-PIPERIDIN-4-YL-3,4-DIHYDROQUINOLIN-2(1H)-ONE, GLYCEROL, Mitogen-activated protein kinase 14 著者 Fitzgerald, C.E, Patel, S.B, Becker, J.W, Cameron, P.M, Zaller, D, Pikounis, V.B, O'Keefe, S.J, Scapin, G. 登録日 2003-03-26 公開日 2003-09-02 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis for p38alpha MAP kinase quinazolinone and pyridol-pyrimidine inhibitor specificity Nat.Struct.Biol., 10, 2003
1OUK	The structure of p38 alpha in complex with a pyridinylimidazole inhibitor 分子名称: 4-[5-[2-(1-PHENYL-ETHYLAMINO)-PYRIMIDIN-4-YL]-1-METHYL-4-(3-TRIFLUOROMETHYLPHENYL)-1H-IMIDAZOL-2-YL]-PIPERIDINE, Mitogen-activated protein kinase 14, SULFATE ION 著者 Fitzgerald, C.E, Patel, S.B, Becker, J.W, Cameron, P.M, Zaller, D, Pikounis, V.B, O'Keefe, S.J, Scapin, G. 登録日 2003-03-24 公開日 2003-09-02 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for p38alpha MAP kinase quinazolinone and pyridol-pyrimidine inhibitor specificity Nat.Struct.Biol., 10, 2003
1OUY	The structure of p38 alpha in complex with a dihydropyrido-pyrimidine inhibitor 分子名称: 1-(2,6-DICHLOROPHENYL)-6-[(2,4-DIFLUOROPHENYL)SULFANYL]-7-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-3,4-DIHYDROPYRIDO[3,2-D]PYRIMIDIN-2(1H)-ONE, Mitogen-activated protein kinase 14 著者 Fitzgerald, C.E, Patel, S.B, Becker, J.W, Cameron, P.M, Zaller, D, Pikounis, V.B, O'Keefe, S.J, Scapin, G. 登録日 2003-03-25 公開日 2003-09-02 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for p38alpha MAP kinase quinazolinone and pyridol-pyrimidine inhibitor specificity Nat.Struct.Biol., 10, 2003
6BJC	TPX2_mini decorated GMPCPP-microtubule 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... 著者 Zhang, R, Nogales, E. 登録日 2017-11-05 公開日 2017-11-22 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural insight into TPX2-stimulated microtubule assembly. Elife, 6, 2017
6T79	Structure of a human nucleosome at 3.2 A resolution 分子名称: DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... 著者 Dodonova, S.O, Zhu, F, Dienemann, C, Taipale, J, Cramer, P. 登録日 2019-10-21 公開日 2020-04-29 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function. Nature, 580, 2020
6T9J	SAGA Tra1 module 分子名称: Transcription factor SPT20, Transcription initiation factor TFIID subunit 12, Transcription-associated protein 1 著者 Wang, H, Cheung, A, Cramer, P. 登録日 2019-10-28 公開日 2020-01-29 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structure of the transcription coactivator SAGA. Nature, 577, 2020
4YNP	ASH1L SET domain S2259M mutant in complex with S-adenosyl methionine (SAM) 分子名称: Histone-lysine N-methyltransferase ASH1L, S-ADENOSYLMETHIONINE, ZINC ION 著者 Rogawski, D.S, Ndoj, J, Cho, H.-J, Maillard, I, Grembecka, J, Cierpicki, T. 登録日 2015-03-10 公開日 2015-09-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Two Loops Undergoing Concerted Dynamics Regulate the Activity of the ASH1L Histone Methyltransferase. Biochemistry, 54, 2015
6TQQ	Structural insight into tanapoxvirus mediated inhibition of apoptosis 分子名称: 16L protein, Bcl-2-like protein 11, SODIUM ION 著者 Suraweera, C.D, Hinds, M.G, Kvansakul, M. 登録日 2019-12-17 公開日 2020-06-03 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (3.0017972 Å) 主引用文献 Structural insight into tanapoxvirus-mediated inhibition of apoptosis. Febs J., 287, 2020
6TIW	Human kinesin-5 motor domain in the GSK state bound to microtubules (Conformation 2) 分子名称: 6-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1~{H}-quinolin-2-one, Kinesin-like protein KIF11, MAGNESIUM ION, ... 著者 Pena, A, Sweeney, A, Cook, A.D, Moores, C.A, Topf, M. 登録日 2019-11-22 公開日 2020-03-04 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy. Structure, 28, 2020
6T9I	cryo-EM structure of transcription coactivator SAGA 分子名称: Protein SPT3, SAGA-associated factor 73, Transcription factor SPT20, ... 著者 Wang, H, Cheung, A, Cramer, P. 登録日 2019-10-28 公開日 2020-01-29 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structure of the transcription coactivator SAGA. Nature, 577, 2020
6TKS	Tankyrase 2 in complex with an inhibitor (OM-1720) 分子名称: Tankyrase-2, ZINC ION, ~{N}-[3-[5-(5-ethoxypyridin-2-yl)-4-(2-fluorophenyl)-1,2,4-triazol-3-yl]cyclobutyl]-1,6-naphthyridine-2-carboxamide 著者 Sowa, S.T, Lehtio, L. 登録日 2019-11-28 公開日 2020-07-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Preclinical Lead Optimization of a 1,2,4-Triazole Based Tankyrase Inhibitor. J.Med.Chem., 63, 2020
6BWD	3.7 angstrom cryoEM structure of truncated mouse TRPM7 分子名称: CHOLESTEROL HEMISUCCINATE, MAGNESIUM ION, Transient receptor potential cation channel subfamily M member 7 著者 Zhang, J, Li, Z, Duan, J, Li, J, Hulse, R.E, Santa-Cruz, A, Abiria, S.A, Krapivinsky, G, Clapham, D.E. 登録日 2017-12-14 公開日 2018-08-15 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structure of the mammalian TRPM7, a magnesium channel required during embryonic development. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6S30	Crystal Structure of Seryl-tRNA Synthetase from Klebsiella pneumoniae 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Serine--tRNA ligase 著者 Pang, L, De Graef, S, Weeks, S.D, Strelkov, S.V. 登録日 2019-06-23 公開日 2020-01-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases. Acs Chem.Biol., 15, 2020
7TB1	Crystal structure of STUB1 with a macrocyclic peptide 分子名称: 1,3-bis(sulfanyl)propan-2-one, ALA-CYS-SER-SER-ILE-TRP-CYS-PRO-ASP-GLY, E3 ubiquitin-protein ligase CHIP 著者 Bahmanjah, S, Klein, D.J. 登録日 2021-12-21 公開日 2022-07-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.785 Å) 主引用文献 Discovery and Structure-Based Design of Macrocyclic Peptides Targeting STUB1. J.Med.Chem., 2022
6CIV	Lactam cyclised mimetic of a fragment of p21 分子名称: p21 著者 Wegener, K.L. 登録日 2018-02-25 公開日 2018-07-04 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Rational Design of a 310-Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp. Chemistry, 24, 2018
6D0Y	X-ray Crystal Structure of PGC-1beta C-terminus bound to the CBP80-CBP20 Cap Binding Complex 分子名称: MAGNESIUM ION, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ... 著者 Gleghorn, M.L, Maquat, L.E. 登録日 2018-04-11 公開日 2018-04-25 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (2.676 Å) 主引用文献 Transcriptional coactivator PGC-1 alpha contains a novel CBP80-binding motif that orchestrates efficient target gene expression. Genes Dev., 32, 2018
6SIE	Crystal structure of the C-lobe of drosophila Arc 2 分子名称: Activity-regulated cytoskeleton associated protein 2, SULFATE ION 著者 Hallin, E.I, Kursula, P. 登録日 2019-08-09 公開日 2019-08-28 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal and solution structures reveal oligomerization of individual capsid homology domains of Drosophila Arc. Plos One, 16, 2021
4YNM	ASH1L wild-type SET domain in complex with S-adenosyl methionine (SAM) 分子名称: Histone-lysine N-methyltransferase ASH1L, S-ADENOSYLMETHIONINE, ZINC ION 著者 Rogawski, D.S, Ndoj, J, Cho, H.-J, Maillard, I, Grembecka, J, Cierpicki, T. 登録日 2015-03-10 公開日 2015-09-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Two Loops Undergoing Concerted Dynamics Regulate the Activity of the ASH1L Histone Methyltransferase. Biochemistry, 54, 2015
1NWM	GAT domain of human GGA1 分子名称: ADP-ribosylation factor binding protein GGA1 著者 Suer, S, Misra, S, Saidi, L.F, Hurley, J.H. 登録日 2003-02-06 公開日 2003-03-25 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of the GAT domain of human GGA1: a syntaxin amino-terminal domain fold in an endosomal trafficking adaptor. Proc.Natl.Acad.Sci.USA, 100, 2003
4YPE	ASH1L SET domain H2193F mutant in complex with S-adenosyl methionine (SAM) 分子名称: Histone-lysine N-methyltransferase ASH1L, S-ADENOSYLMETHIONINE, ZINC ION 著者 Rogawski, D.S, Ndoj, J, Cho, H.J, Maillard, I, Grembecka, J, Cierpicki, T. 登録日 2015-03-12 公開日 2015-09-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Two Loops Undergoing Concerted Dynamics Regulate the Activity of the ASH1L Histone Methyltransferase. Biochemistry, 54, 2015

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