6T7D

Structure of human Sox11 transcription factor in complex with a nucleosome

Summary for 6T7D

• Entry DOI: 10.2210/pdb6t7d/pdb
• EMDB information: 10394
• Descriptor: Histone H3.2, Histone H4, Histone H2A type 1-B/E, ... (7 entities in total)
• Functional Keywords: nucleosome, dna, histones, sox11, transcription factor, pioneer factor, nuclear protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 11
• Total formula weight: 220878.52

Authors

Dodonova, S.O.,Zhu, F.,Dienemann, C.,Taipale, J.,Cramer, P. (deposition date: 2019-10-21, release date: 2020-04-29, Last modification date: 2024-05-22)

• Primary citation: Dodonova, S.O.,Zhu, F.,Dienemann, C.,Taipale, J.,Cramer, P.; Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function.; Nature, 580:669-672, 2020; PubMed: 32350470; DOI: 10.1038/s41586-020-2195-y

Experimental method

ELECTRON MICROSCOPY (4.4 Å)