Lactam cyclised mimetic of a fragment of p21

Summary for 6CIV

Related6CEJ 6CIX
Descriptorp21 (1 entity in total)
Functional Keywordspip-box motif, p21, constrained, peptidomimetic, biosynthetic protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total molecular weight1801.06
Wegener, K.L. (deposition date: 2018-02-25, release date: 2018-07-04, Last modification date: 2018-08-29)
Primary citation
Wegener, K.L.,McGrath, A.E.,Dixon, N.E.,Oakley, A.J.,Scanlon, D.B.,Abell, A.D.,Bruning, J.B.
Rational Design of a 310-Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp.
Chemistry, 24:11325-11331, 2018
PubMed: 29917264 (PDB entries with the same primary citation)
DOI: 10.1002/chem.201801734
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers22.3%2.1%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures

More Asymmetric unit images

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