6S30

Crystal Structure of Seryl-tRNA Synthetase from Klebsiella pneumoniae

Summary for 6S30

Entry DOI	10.2210/pdb6s30/pdb
Related	6HDZ 6HE1 6HE3 6HHV 6HHW 6HHX 6HHY 6HHZ 6HI0 6RLT 6RLU 6RLV
Descriptor	Serine--tRNA ligase, 1,2-ETHANEDIOL, CALCIUM ION, ... (4 entities in total)
Functional Keywords	coil-coil, beta barrel, trna synthetase, inhibitor, complex, ligase
Biological source	Klebsiella pneumoniae
Total number of polymer chains	1
Total formula weight	48913.55
Authors	Pang, L.,De Graef, S.,Weeks, S.D.,Strelkov, S.V. (deposition date: 2019-06-23, release date: 2020-01-08, Last modification date: 2024-01-24)
Primary citation	Pang, L.,Nautiyal, M.,De Graef, S.,Gadakh, B.,Zorzini, V.,Economou, A.,Strelkov, S.V.,Van Aerschot, A.,Weeks, S.D. Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases. Acs Chem.Biol., 15:407-415, 2020 Cited by PubMed: 31869198 DOI: 10.1021/acschembio.9b00887 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.41 Å)

Structure validation