PDB: 17012 件ウェブページステータス検索Chemie searchBIRD

---

3KV4	Structure of PHF8 in complex with histone H3 分子名称: 1,2-ETHANEDIOL, FE (II) ION, Histone H3-like, ... 著者 Horton, J.R, Upadhyay, A.K, Qi, H.H, Zhang, X, Shi, Y, Cheng, X. 登録日 2009-11-29 公開日 2009-12-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases. Nat.Struct.Mol.Biol., 17, 2010
5VR7	ABA-mimicking ligand AMF1alpha in complex with ABA receptor PYL2 and PP2C HAB1 分子名称: 1-(2-fluoro-4-methylphenyl)-N-(2-oxo-1-propyl-1,2,3,4-tetrahydroquinolin-6-yl)methanesulfonamide, Abscisic acid receptor PYL2, MAGNESIUM ION, ... 著者 Cao, M.-J, Zhang, Y.-L, Liu, X, Huang, H, Zhou, X.E, Wang, W.-L, Zeng, A, Zhao, C.-Z, Si, T, Du, J.-M, Wu, W.-W, Wang, F.-X, Xu, H.E, Zhu, J.-K. 登録日 2017-05-10 公開日 2017-11-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.612 Å) 主引用文献 Combining chemical and genetic approaches to increase drought resistance in plants. Nat Commun, 8, 2017
4Z34	Crystal Structure of Human Lysophosphatidic Acid Receptor 1 in complex with ONO9780307 分子名称: (2S)-2,3-dihydroxypropyl (7Z)-tetradec-7-enoate, Lysophosphatidic acid receptor 1, Soluble cytochrome b562, ... 著者 Chrencik, J.E, Roth, C.B, Terakado, M, Kurata, H, Omi, R, Kihara, Y, Warshaviak, D, Nakade, S, Asmar-Rovira, G, Mileni, M, Mizuno, H, Griffith, M.T, Rodgers, C, Han, G.W, Velasquez, J, Chun, J, Stevens, R.C, Hanson, M.A, GPCR Network (GPCR) 登録日 2015-03-30 公開日 2015-06-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1. Cell, 161, 2015
3KVK	Crystal structure of human dihydroorotate dehydrogenase (DHODH) with amino-benzoic acid inhibitor 641 at 2.05A resolution 分子名称: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, 2-{[(3,5-dichlorophenyl)carbamoyl]amino}benzoic acid, Dihydroorotate dehydrogenase, ... 著者 McLean, L, Zhang, Y. 登録日 2009-11-30 公開日 2010-03-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Discovery of novel inhibitors for DHODH via virtual screening and X-ray crystallographic structures. Bioorg.Med.Chem.Lett., 20, 2010
5VEP	MOUSE KYNURENINE AMINOTRANSFERASE III, RE-REFINEMENT OF THE PDB STRUCTURE 3E2F 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... 著者 Wlodawer, A, Dauter, Z, Minor, W, Stanfield, R, Porebski, P, Jaskolski, M, Pozharski, E, Weichenberger, C.X, Rupp, B. 登録日 2017-04-05 公開日 2017-11-29 最終更新日 2022-04-13 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Detect, correct, retract: How to manage incorrect structural models. FEBS J., 285, 2018
3KXV	Structure of complement Factor H variant Q1139A 分子名称: Complement factor H, SULFATE ION 著者 Bhattacharjee, A, Lehtinen, M.J, Kajander, T, Goldman, A, Jokiranta, T.S. 登録日 2009-12-04 公開日 2010-05-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.004 Å) 主引用文献 Both domain 19 and domain 20 of factor H are involved in binding to complement C3b and C3d Mol.Immunol., 47, 2010
5VS1	Human DNA polymerase beta pre-catalytic 8-oxoG:dA extension complex with dTTP bound in non-planar conformation 分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*CP*CP*GP*AP*CP*AP*(8OG)P*GP*CP*GP*CP*AP*TP*CP*AP*G)-3'), ... 著者 Reed, A.J, Suo, Z. 登録日 2017-05-11 公開日 2017-07-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Time-Dependent Extension from an 8-Oxoguanine Lesion by Human DNA Polymerase Beta. J. Am. Chem. Soc., 139, 2017
1T2U	Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1: structure of BRCA1 missense variant V1809F 分子名称: Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION 著者 Williams, R.S, Lee, M.S, Duong, D.D, Glover, J.N.M. 登録日 2004-04-22 公開日 2004-05-11 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural Basis of Phosphopeptide recognition by the BRCT domain of BRCA1 Nat.Struct.Mol.Biol., 11, 2004
1ATT	CRYSTAL STRUCTURE OF CLEAVED BOVINE ANTITHROMBIN III AT 3.2 ANGSTROMS RESOLUTION 分子名称: ANTITHROMBIN III 著者 Mourey, L, Samama, J.P, Delarue, M, Moras, D. 登録日 1993-03-29 公開日 1994-07-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structure of cleaved bovine antithrombin III at 3.2 A resolution. J.Mol.Biol., 232, 1993
1AQM	ALPHA-AMYLASE FROM ALTEROMONAS HALOPLANCTIS COMPLEXED WITH TRIS 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ALPHA-AMYLASE, CALCIUM ION, ... 著者 Aghajari, N, Haser, R. 登録日 1997-07-31 公開日 1999-03-02 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structures of the psychrophilic alpha-amylase from Alteromonas haloplanctis in its native form and complexed with an inhibitor. Protein Sci., 7, 1998
5VDQ	Human cyclic GMP-AMP synthase (cGAS) in complex with 2',5'-GpAp 分子名称: 2',5'-GpAp, Cyclic GMP-AMP synthase, ZINC ION 著者 Byrnes, L.J, Hall, J.D. 登録日 2017-04-03 公開日 2017-09-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.246 Å) 主引用文献 The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition. Protein Sci., 26, 2017
4ZGA	Structural basis for inhibition of human autotaxin by four novel compounds 分子名称: (11aS)-6-(4-fluorobenzyl)-5,6,11,11a-tetrahydro-1H-imidazo[1',5':1,6]pyrido[3,4-b]indole-1,3(2H)-dione, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Stein, A.J, Bain, G, Hutchinson, J.H, Evans, J.F. 登録日 2015-04-22 公開日 2015-10-14 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Basis for Inhibition of Human Autotaxin by Four Potent Compounds with Distinct Modes of Binding. Mol.Pharmacol., 88, 2015
1T3G	Crystal structure of the Toll/interleukin-1 receptor (TIR) domain of human IL-1RAPL 分子名称: X-linked interleukin-1 receptor accessory protein-like 1 著者 Khan, J.A, Tong, L. 登録日 2004-04-26 公開日 2005-02-08 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of the Toll/interleukin-1 receptor domain of human IL-1RAPL J.Biol.Chem., 279, 2004
3HO3	Crystal structure of Hedgehog-interacting protein (HHIP) 分子名称: Hedgehog-interacting protein 著者 Bosanac, I, Hymowitz, S.G. 登録日 2009-06-01 公開日 2009-06-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling. Nat.Struct.Mol.Biol., 16, 2009
5V9L	KRAS G12C in bound to quinazoline based switch II pocket (SWIIP) binder 分子名称: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Westover, K, Lu, J. 登録日 2017-03-23 公開日 2017-08-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.981 Å) 主引用文献 Potent and Selective Covalent Quinazoline Inhibitors of KRAS G12C. Cell Chem Biol, 24, 2017
5VCG	Crystal structure of the cysteine depleted CYP3A4 bound to bromoergocryptine 分子名称: Cytochrome P450 3A4, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Sevrioukova, I. 登録日 2017-03-31 公開日 2017-05-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 High-Level Production and Properties of the Cysteine-Depleted Cytochrome P450 3A4. Biochemistry, 56, 2017
4ZPQ	Crystal Structure of Protocadherin Gamma C5 EC1-3 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, MCG133388, ... 著者 Wolcott, H.N, Goodman, K.M, Bahna, F, Mannepalli, S, Shapiro, L. 登録日 2015-05-08 公開日 2015-10-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.099 Å) 主引用文献 Molecular Logic of Neuronal Self-Recognition through Protocadherin Domain Interactions. Cell, 163, 2015
5V3A	Novel Structural Insights into GDP-Mediated Regulation of Acyl-CoA Thioesterases 分子名称: Acyl-CoA hydrolase, COENZYME A, GUANOSINE-5'-DIPHOSPHATE 著者 Khandokar, Y.B, Srivastava, P, Forwood, J.K. 登録日 2017-03-06 公開日 2017-05-24 最終更新日 2017-12-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural insights into GDP-mediated regulation of a bacterial acyl-CoA thioesterase. J. Biol. Chem., 292, 2017
3HMK	Crystal Structure of Serine Racemase 分子名称: MANGANESE (II) ION, PYRIDOXAL-5'-PHOSPHATE, Serine racemase 著者 Smith, M.A, Barker, J, Mack, V, Ebneth, A, Felicetti, B, Woods, M. 登録日 2009-05-29 公開日 2010-01-26 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The structure of mammalian serine racemase: evidence for conformational changes upon inhibitor binding. J.Biol.Chem., 285, 2010
1TAZ	Catalytic Domain Of Human Phosphodiesterase 1B 分子名称: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, MAGNESIUM ION, ZINC ION 著者 Zhang, K.Y.J, Card, G.L, Suzuki, Y, Artis, D.R, Fong, D, Gillette, S, Hsieh, D, Neiman, J, West, B.L, Zhang, C, Milburn, M.V, Kim, S.-H, Schlessinger, J, Bollag, G. 登録日 2004-05-19 公開日 2004-08-03 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 A Glutamine Switch Mechanism for Nucleotide Selectivity by Phosphodiesterases Mol.Cell, 15, 2004
1BH8	HTAFII18/HTAFII28 HETERODIMER CRYSTAL STRUCTURE 分子名称: TAFII18, TAFII28 著者 Birck, C, Poch, O, Romier, C, Ruff, M, Mengus, G, Lavigne, A.-C, Davidson, I, Moras, D. 登録日 1998-06-16 公開日 1999-06-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Human TAF(II)28 and TAF(II)18 interact through a histone fold encoded by atypical evolutionary conserved motifs also found in the SPT3 family. Cell(Cambridge,Mass.), 94, 1998
3I3F	Hypothetical protein from Giardia lamblia GL50803_14299 分子名称: BUTANOIC ACID, Hypothetical protein, PENTANOIC ACID 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2009-06-30 公開日 2009-09-01 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Hypothetical protein from Giardia lamblia GL50803_14299 To be Published
5UIP	structure of DHFR with bound DAP, p-ABG and NADP 分子名称: Dihydrofolate reductase, N-(4-aminobenzene-1-carbonyl)-L-glutamic acid, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Pedersen, L.C, London, R.E. 登録日 2017-01-14 公開日 2017-11-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A Structural Basis for Biguanide Activity. Biochemistry, 56, 2017
4ZGY	STRUCTURE of HUMAN ORNITHINE DECARBOXYLASE IN COMPLEX WITH A C-TERMINAL FRAGMENT OF ANTIZYME 分子名称: MAGNESIUM ION, Ornithine decarboxylase, Ornithine decarboxylase antizyme 1, ... 著者 Wu, H.Y, Chan, N.L. 登録日 2015-04-24 公開日 2015-09-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 Structural basis of antizyme-mediated regulation of polyamine homeostasis Proc.Natl.Acad.Sci.USA, 112, 2015
1UQS	The Crystal Structure of Human CD1b with a Bound Bacterial Glycolipid 分子名称: BETA-2-MICROGLOBULIN, GLUCOSE MONOMYCOLATE, T-CELL SURFACE GLYCOPROTEIN CD1B 著者 Batuwangala, T, Shepherd, D, Gadola, S.D, Gibson, K.J.C, Zaccai, N.R, Besra, G.S, Cerundolo, V, Jones, E.Y. 登録日 2003-10-16 公開日 2003-10-30 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The crystal structure of human CD1b with a bound bacterial glycolipid. J Immunol., 172, 2004

<454455456457458459460461462463464465466467468469>