5VCG
Crystal structure of the cysteine depleted CYP3A4 bound to bromoergocryptine
Summary for 5VCG
| Entry DOI | 10.2210/pdb5vcg/pdb |
| Related | 5VC0 5VCC 5VCD 5VCE |
| Descriptor | Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, bromoergocryptine, ... (5 entities in total) |
| Functional Keywords | cytochrome p450, cyp3a4, monooxygenase, cysteine mutation, bromoergocryprine, oxidoreductase-substrate complex, oxidoreductase/substrate |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 57311.03 |
| Authors | Sevrioukova, I. (deposition date: 2017-03-31, release date: 2017-05-31, Last modification date: 2023-10-04) |
| Primary citation | Sevrioukova, I.F. High-Level Production and Properties of the Cysteine-Depleted Cytochrome P450 3A4. Biochemistry, 56:3058-3067, 2017 Cited by PubMed: 28590129DOI: 10.1021/acs.biochem.7b00334 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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