6B8P
 
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6I8V
 | | KtrC with ATP bound | | 分子名称: | 1,4-BUTANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ... | | 著者 | Rocha, R, Morais-Cabral, J.H. | | 登録日 | 2018-11-21 | | 公開日 | 2019-10-30 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.991 Å) | | 主引用文献 | Characterization of the molecular properties of KtrC, a second RCK domain that regulates a Ktr channel in Bacillus subtilis.
J.Struct.Biol., 205, 2019
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8D3Y
 | | Human alpha3 Na+/K+-ATPase in its exoplasmic side-open state | | 分子名称: | FXYD domain-containing ion transport regulator 6, Sodium/potassium-transporting ATPase subunit alpha-3, Sodium/potassium-transporting ATPase subunit beta-1 | | 著者 | Nguyen, P.T, Bai, X. | | 登録日 | 2022-06-01 | | 公開日 | 2022-09-21 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural basis for gating mechanism of the human sodium-potassium pump.
Nat Commun, 13, 2022
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8D3X
 | | Human alpha3 Na+/K+-ATPase in its K+-occluded state | | 分子名称: | FXYD domain-containing ion transport regulator 6, Sodium/potassium-transporting ATPase subunit alpha-3, Sodium/potassium-transporting ATPase subunit beta-1, ... | | 著者 | Nguyen, P.T, Bai, X. | | 登録日 | 2022-06-01 | | 公開日 | 2022-09-21 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural basis for gating mechanism of the human sodium-potassium pump.
Nat Commun, 13, 2022
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8D3U
 | | Human alpha3 Na+/K+-ATPase in its Na+-occluded state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, FXYD domain-containing ion transport regulator 6, Sodium/potassium-transporting ATPase subunit alpha-3, ... | | 著者 | Nguyen, P.T, Bai, X. | | 登録日 | 2022-06-01 | | 公開日 | 2022-09-21 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural basis for gating mechanism of the human sodium-potassium pump.
Nat Commun, 13, 2022
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8D3W
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8D3V
 | | Human alpha3 Na+/K+-ATPase in its cytoplasmic side-open state | | 分子名称: | FXYD domain-containing ion transport regulator 6, Sodium/potassium-transporting ATPase subunit alpha-3, Sodium/potassium-transporting ATPase subunit beta-1 | | 著者 | Nguyen, P.T, Bai, X. | | 登録日 | 2022-06-01 | | 公開日 | 2022-09-21 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural basis for gating mechanism of the human sodium-potassium pump.
Nat Commun, 13, 2022
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6DU8
 | | Human Polycsytin 2-l1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Polycystic kidney disease 2-like 1 protein | | 著者 | Hulse, R.E, Clapham, D.E, Li, Z, Huang, R.K, Zhang, J. | | 登録日 | 2018-06-20 | | 公開日 | 2018-07-25 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | | 主引用文献 | Cryo-EM structure of the polycystin 2-l1 ion channel.
Elife, 7, 2018
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6NZZ
 | | LRRC8A-DCPIB in MSP1E3D1 nanodisc expanded state | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 4-{[(2S)-2-butyl-6,7-dichloro-2-cyclopentyl-1-oxo-2,3-dihydro-1H-inden-5-yl]oxy}butanoic acid, Volume-regulated anion channel subunit LRRC8A | | 著者 | Kern, D.M, Hite, R.K, Brohawn, S.G. | | 登録日 | 2019-02-14 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | | 主引用文献 | Cryo-EM structures of the DCPIB-inhibited volume-regulated anion channel LRRC8A in lipid nanodiscs.
Elife, 8, 2019
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6O00
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6NZW
 | | LRRC8A-DCPIB in MSP1E3D1 nanodisc constricted state | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 4-{[(2S)-2-butyl-6,7-dichloro-2-cyclopentyl-1-oxo-2,3-dihydro-1H-inden-5-yl]oxy}butanoic acid, Volume-regulated anion channel subunit LRRC8A | | 著者 | Kern, D.M, Hite, R.K, Brohawn, S.G. | | 登録日 | 2019-02-14 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | | 主引用文献 | Cryo-EM structures of the DCPIB-inhibited volume-regulated anion channel LRRC8A in lipid nanodiscs.
Elife, 8, 2019
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6AUP
 | | Exploring Cystine Dense Peptide Space to Open a Unique Molecular Toolbox | | 分子名称: | GLYCEROL, Potassium channel toxin gamma-KTx 2.2, SULFATE ION | | 著者 | Gewe, M.M, Rupert, P, Strong, R.K. | | 登録日 | 2017-09-01 | | 公開日 | 2018-02-28 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Screening, large-scale production and structure-based classification of cystine-dense peptides.
Nat. Struct. Mol. Biol., 25, 2018
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6AU7
 | | Exploring Cystine Dense Peptide Space to Open a Unique Molecular Toolbox | | 分子名称: | GLYCEROL, Potassium channel toxin gamma-KTx 2.2, SULFATE ION | | 著者 | Gewe, M.M, Rupert, P, Strong, R.K. | | 登録日 | 2017-08-30 | | 公開日 | 2018-02-28 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Screening, large-scale production and structure-based classification of cystine-dense peptides.
Nat. Struct. Mol. Biol., 25, 2018
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5TJA
 | | I-II linker of TRPML1 channel at pH 6 | | 分子名称: | Mucolipin-1 | | 著者 | Li, M, Zhang, W.K, Benvin, N.M, Zhou, X, Su, D, Li, H, Wang, S, Michailidis, I.E, Tong, L, Li, X, Yang, J. | | 登録日 | 2016-10-04 | | 公開日 | 2017-01-25 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis of dual Ca(2+)/pH regulation of the endolysosomal TRPML1 channel.
Nat. Struct. Mol. Biol., 24, 2017
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7CU3
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7RXQ
 | | Crystal structure of junctophilin-2 in complex with a CaV1.1 peptide | | 分子名称: | ETHANOL, Junctophilin-2 N-terminal fragment, SULFATE ION, ... | | 著者 | Yang, Z, Panwar, P, Van Petegem, F. | | 登録日 | 2021-08-23 | | 公開日 | 2022-02-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Structures of the junctophilin/voltage-gated calcium channel interface reveal hot spot for cardiomyopathy mutations.
Proc.Natl.Acad.Sci.USA, 119, 2022
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6DAH
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6B8Q
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6BGJ
 | | Cryo-EM structure of the TMEM16A calcium-activated chloride channel in LMNG | | 分子名称: | Anoctamin-1, CALCIUM ION | | 著者 | Dang, S, Feng, S, Tien, J, Peters, C.J, Bulkley, D, Lolicato, M, Zhao, J, Zuberbuhler, K, Ye, W, Qi, L, Chen, T, Craik, C.S, Jan, Y.N, Minor Jr, D.L, Cheng, Y, Jan, L.Y. | | 登録日 | 2017-10-28 | | 公開日 | 2017-12-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Cryo-EM structures of the TMEM16A calcium-activated chloride channel.
Nature, 552, 2017
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6BGI
 | | Cryo-EM structure of the TMEM16A calcium-activated chloride channel in nanodisc | | 分子名称: | Anoctamin-1, CALCIUM ION | | 著者 | Dang, S, Feng, S, Tien, J, Peters, C.J, Bulkley, D, Lolicato, M, Zhao, J, Zuberbuhler, K, Ye, W, Qi, J, Chen, T, Craik, C.S, Jan, Y.N, Minor Jr, D.L, Cheng, Y, Jan, L.Y. | | 登録日 | 2017-10-28 | | 公開日 | 2017-12-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Cryo-EM structures of the TMEM16A calcium-activated chloride channel.
Nature, 552, 2017
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6FIZ
 | | Crystal Structure of CNG mimicking NaK-EAPP mutant (T67A) cocrystallized with K+ | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCINE, POTASSIUM ION, ... | | 著者 | Napolitano, L.M.R, De March, M, Steiner, R.A, Onesti, S. | | 登録日 | 2018-01-19 | | 公開日 | 2019-03-06 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | | 主引用文献 | Crystal Structure of CNG mimicking NaK-EAPP mutant (T67A) cocrystallized with K+
To Be Published
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4OVN
 | | Voltage-gated Sodium Channel 1.5 (Nav1.5) C-terminal domain in complex with Calmodulin poised for activation | | 分子名称: | Calmodulin, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Gabelli, S.B, Bianchet, M.A, Boto, A, Jakoncic, J, Tomaselli, G.F, Amzel, L.M. | | 登録日 | 2013-12-10 | | 公開日 | 2014-12-03 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Regulation of the NaV1.5 cytoplasmic domain by calmodulin.
Nat Commun, 5, 2014
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2VAY
 | | Calmodulin complexed with CaV1.1 IQ peptide | | 分子名称: | CALCIUM ION, CALMODULIN, CHLORIDE ION, ... | | 著者 | Halling, D.B, Black, D.J, Pedersen, S.E, Hamilton, S.L. | | 登録日 | 2007-09-05 | | 公開日 | 2008-09-16 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Determinants in Cav1 Channels that Regulate the Ca2+ Sensitivity of Bound Calmodulin.
J.Biol.Chem., 284, 2009
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3J41
 | | Pseudo-atomic model of the Aquaporin-0/Calmodulin complex derived from electron microscopy | | 分子名称: | CALCIUM ION, Calmodulin, Lens fiber major intrinsic protein | | 著者 | Reichow, S.L, Clemens, D.M, Freites, J.A, Nemeth-Cahalan, K.L, Heyden, M, Tobias, D.J, Hall, J.E, Gonen, T. | | 登録日 | 2013-05-31 | | 公開日 | 2013-07-31 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (25 Å) | | 主引用文献 | Allosteric mechanism of water-channel gating by Ca(2+)-calmodulin.
Nat.Struct.Mol.Biol., 20, 2013
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2KJ1
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