PDB: 2866 件ウェブページステータス検索Chemie searchBIRD

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8B3F	Pol II-CSB-CSA-DDB1-ELOF1 分子名称: DNA damage-binding protein 1, DNA excision repair protein ERCC-6, DNA excision repair protein ERCC-8, ... 著者 Kokic, G, Cramer, P. 登録日 2022-09-16 公開日 2023-09-27 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Pol II-CSB-CSA-DDB1-ELOF1 structure. To Be Published
9IPU	cryo-EM structure of the RNF168(1-193)/UbcH5c-Ub ubiquitylation module bound to H1.0-K63-Ub3 modified chromatosome 分子名称: DNA (171-MER), E3 ubiquitin-protein ligase RNF168, Histone H1.0, ... 著者 Ai, H.S, Deng, Z.H, Liu, L. 登録日 2024-07-11 公開日 2024-10-02 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Chemically and Site-specifically Ubiquitylated Linker Histone H1 Facilitates RNF168-Mediated Nucleosomal H2A Ubiquitylation To Be Published
8QMA	Structure of the plastid-encoded RNA polymerase complex (PEP) from Sinapis alba 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 do Prado, P.F.V, Ahrens, F.M, Pfannschmidt, T, Hillen, H.S. 登録日 2023-09-21 公開日 2024-03-06 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structure of the multi-subunit chloroplast RNA polymerase. Mol.Cell, 84, 2024
8WA1	The cryo-EM structure of the Nicotiana tabacum PEP-PAP-TEC2 分子名称: DNA (24-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Wu, X.X, Zhang, Y. 登録日 2023-09-06 公開日 2024-03-13 最終更新日 2024-10-30 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Cryo-EM structures of the plant plastid-encoded RNA polymerase. Cell, 187, 2024
8WA0	The cryo-EM structure of the Nicotiana tabacum PEP-PAP-TEC1 分子名称: DNA (48-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Wu, X.X, Zhang, Y. 登録日 2023-09-06 公開日 2024-03-13 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Cryo-EM structures of the plant plastid-encoded RNA polymerase. Cell, 187, 2024
6EKM	Crystal structure of mammalian Rev7 in complex with human Rev3 second binding site 分子名称: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B 著者 Huber, F, Tropia, L, Emamzadah, S, Halazonetis, T. 登録日 2017-09-26 公開日 2018-10-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Crystal structure of mammalian Rev7 in complex with human Rev3 To Be Published
8W9Z	The cryo-EM structure of the Nicotiana tabacum PEP-PAP 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta'', ... 著者 Wu, X.X, Zhang, Y. 登録日 2023-09-06 公開日 2024-03-13 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Cryo-EM structures of the plant plastid-encoded RNA polymerase. Cell, 187, 2024
8CEO	Yeast RNA polymerase II transcription pre-initiation complex with core Mediator and the +1 nucleosome 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Wang, H, Cramer, P. 登録日 2023-02-02 公開日 2023-03-08 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain. Proc.Natl.Acad.Sci.USA, 120, 2023
8CEN	Yeast RNA polymerase II transcription pre-initiation complex with core Mediator 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Wang, H, Schilbach, S, Cramer, P. 登録日 2023-02-02 公開日 2023-03-22 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain. Proc.Natl.Acad.Sci.USA, 120, 2023
4TZ4	Crystal Structure of Human Cereblon in Complex with DDB1 and Lenalidomide 分子名称: DNA damage-binding protein 1, Protein cereblon, S-Lenalidomide, ... 著者 Chamberlain, P.P, Pagarigan, B, Delker, S, Leon, B, Riley, M. 登録日 2014-07-09 公開日 2014-08-06 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 Structural Basis for Responsiveness to Thalidomide-Analog Drugs Defined by the Crystal Structure of the Human Cereblon:DDB1:Lenalidomide Complex To Be Published
8OF0	Structure of the mammalian Pol II-SPT6-Elongin complex, Structure 1 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... 著者 Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P. 登録日 2023-03-13 公開日 2023-10-18 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (3.05 Å) 主引用文献 Structure of the transcribing RNA polymerase II-Elongin complex. Nat.Struct.Mol.Biol., 30, 2023
8OEV	Structure of the mammalian Pol II-SPT6-Elongin complex, lacking ELOA latch (composite structure, structure 3) 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... 著者 Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P. 登録日 2023-03-13 公開日 2023-10-18 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (2.86 Å) 主引用文献 Structure of the transcribing RNA polymerase II-Elongin complex. Nat.Struct.Mol.Biol., 30, 2023
8OEW	Structure of the mammalian Pol II-Elongin complex, lacking the ELOA latch (composite structure, structure 2) 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... 著者 Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P. 登録日 2023-03-13 公開日 2023-10-18 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structure of the transcribing RNA polymerase II-Elongin complex. Nat.Struct.Mol.Biol., 30, 2023
6DRD	RNA Pol II(G) 分子名称: DNA-directed RNA polymerase II subunit GRINL1A, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11-a, ... 著者 Yu, X, Jishage, M, Shi, Y, Ganesan, S, Sali, A, Chait, B.T, Asturias, F, Roeder, R.G. 登録日 2018-06-11 公開日 2019-06-12 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1. Nat. Struct. Mol. Biol., 25, 2018
6R75	Crystal structure of human Ube2T E54R mutant 分子名称: Ubiquitin-conjugating enzyme E2 T 著者 Chaugule, V.K, Rennie, M.L, Walden, H, Arkinson, C, Kamarainen, O, Toth, R. 登録日 2019-03-28 公開日 2019-10-16 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Allosteric mechanism for site-specific ubiquitination of FANCD2. Nat.Chem.Biol., 16, 2020
7YCX	The structure of INTAC-PEC complex 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1,DNA-directed RNA polymerase II subunit RPB1, ... 著者 Zheng, H, Jin, Q, Wang, X, Qi, Y, Liu, W, Ren, Y, Zhao, D, Chen, F.X, Cheng, J, Chen, X, Xu, Y. 登録日 2022-07-02 公開日 2023-03-15 最終更新日 2023-09-27 実験手法 ELECTRON MICROSCOPY (4.18 Å) 主引用文献 Structural basis of INTAC-regulated transcription. Protein Cell, 14, 2023
8PP7	human RYBP-PRC1 bound to mononucleosome 分子名称: DNA (215-mer), E3 ubiquitin-protein ligase RING2, Histone H2A, ... 著者 Ciapponi, M, Benda, C, Mueller, J. 登録日 2023-07-06 公開日 2024-03-27 最終更新日 2024-07-31 実験手法 ELECTRON MICROSCOPY (2.91 Å) 主引用文献 Structural basis of the histone ubiquitination read-write mechanism of RYBP-PRC1. Nat.Struct.Mol.Biol., 31, 2024
4EXT	Structure of polymerase-interacting domain of human Rev1 in complex with translesional synthesis polymerase zeta 分子名称: DNA repair protein REV1, Mitotic spindle assembly checkpoint protein MAD2B, peptide from DNA polymerase zeta catalytic subunit 著者 Liu, D.N, Ryu, K.S, Ko, J.S, Choi, B.S. 登録日 2012-05-01 公開日 2013-05-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Insights into the scaffold mechanism of human Rev1 in translesional synthesis revealed by structural studies on its polymerase-interacting domain To be Published
5O8K	Crystal structure of mammalian Rev7 in complex with Rev3 1875-1895 分子名称: DNA polymerase zeta catalytic subunit, Mitotic spindle assembly checkpoint protein MAD2B 著者 Emamzadah, S, Tropia, L, Huber, F, Halazonetis, T. 登録日 2017-06-13 公開日 2018-06-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of mammalian Rev7 in complex with Rev3 1875-1895 To Be Published
8U17	The ternary complex structure of DDB1-CRBN-SALL4(ZF1,2)-long bound to Pomalidomide 分子名称: DNA damage-binding protein 1, Protein cereblon, S-Pomalidomide, ... 著者 Clifton, M.C, Ma, X, Ornelas, E. 登録日 2023-08-30 公開日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural and biophysical comparisons of the pomalidomide- and CC-220-induced interactions of SALL4 with cereblon. Sci Rep, 13, 2023
8QU8	PROTAC-mediated complex of KRAS with VHL/Elongin-B/Elongin-C/Cullin-2/Rbx1 分子名称: (2S,4R)-1-[(2S)-2-[4-[4-[(3S)-4-[4-[5-[(4S)-2-azanyl-3-cyano-4-methyl-6,7-dihydro-5H-1-benzothiophen-4-yl]-1,2,4-oxadiazol-3-yl]pyrimidin-2-yl]-3-methyl-1,4-diazepan-1-yl]butoxy]-1,2,3-triazol-1-yl]-3-methyl-butanoyl]-N-[(1R)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]-2-oxidanyl-ethyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... 著者 Fischer, G, Peter, D, Arce-Solano, S. 登録日 2023-10-14 公開日 2023-12-06 最終更新日 2024-10-02 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Targeting cancer with small-molecule pan-KRAS degraders. Science, 385, 2024
8QH5	CryoEM structure of UVSSA(VHS)-CSA-DDB1-DDA1 分子名称: DET1- and DDB1-associated protein 1, DNA damage-binding protein 1, DNA excision repair protein ERCC-8, ... 著者 Lee, S.-H, Sixma, T.K. 登録日 2023-09-06 公開日 2024-08-14 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 CryoEM structure of UVSSA(VHS)-CSA-DDB1-DDA1 To Be Published
8BYA	Cryo-EM structure of SKP1-SKP2-CKS1-CDK2-CyclinA-p27KIP1 Complex 分子名称: Cyclin-A2, Cyclin-dependent kinase 2, Cyclin-dependent kinase inhibitor 1B, ... 著者 Rowland, R.J, Salamina, M, Endicott, J.A, Noble, M.E. 登録日 2022-12-12 公開日 2023-06-28 最終更新日 2023-07-19 実験手法 ELECTRON MICROSCOPY (3.38 Å) 主引用文献 Cryo-EM structure of SKP1-SKP2-CKS1 in complex with CDK2-cyclin A-p27KIP1. Sci Rep, 13, 2023
8B3I	CRL4CSA-E2-Ub (state 2) 分子名称: Cullin-4A, DNA damage-binding protein 1, DNA excision repair protein ERCC-8, ... 著者 Kokic, G, Cramer, P. 登録日 2022-09-16 公開日 2023-09-27 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 C(N)RL4CSA-E2-Ub (state 2) To Be Published
5AVM	Crystal structures of 5-aminoimidazole ribonucleotide (AIR) synthetase, PurM, from Thermus thermophilus 分子名称: Phosphoribosylformylglycinamidine cyclo-ligase, SULFATE ION 著者 Kanagawa, M, Baba, S, Watanabe, Y, Nakagawa, N, Ebihara, A, Sampei, G, Kawai, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2015-06-23 公開日 2015-11-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structures and ligand binding of PurM proteins from Thermus thermophilus and Geobacillus kaustophilus J.Biochem., 159, 2016

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