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1N33
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Structure of the Thermus thermophilus 30S ribosomal subunit bound to codon and near-cognate transfer rna anticodon stem-loop mismatched at the second codon position at the a site with paromomycin
分子名称: 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ...
著者Ogle, J.M, Murphy IV, F.V, Tarry, M.J, Ramakrishnan, V.
登録日2002-10-25
公開日2002-11-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Selection of tRNA by the Ribosome Requires a Transition from an Open to a Closed Form
Cell(Cambridge,Mass.), 111, 2002
4P5D
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CRYSTAL STRUCTURE OF RAT DNPH1 (RCL) WITH 6-NAPHTHYL-PURINE-RIBOSIDE-MONOPHOSPHATE
分子名称: 2'-deoxynucleoside 5'-phosphate N-hydrolase 1, 6-(naphthalen-2-yl)-9-(5-O-phosphono-beta-D-ribofuranosyl)-9H-purine, SULFATE ION
著者Padilla, A, Labesse, G, Kaminski, P.A.
登録日2014-03-16
公開日2014-08-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献6-(Hetero)Arylpurine nucleotides as inhibitors of the oncogenic target DNPH1: Synthesis, structural studies and cytotoxic activities.
Eur.J.Med.Chem., 85C, 2014
5HQN
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Catalytic domain of murine Acid Sphingomyelinase (ASMase, ASM, SMPD1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gorelik, A, Illes, K, Heinz, L.X, Superti-Furga, G, Nagar, B.
登録日2016-01-21
公開日2016-07-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of mammalian acid sphingomyelinase.
Nat Commun, 7, 2016
5W0W
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Crystal structure of Protein Phosphatase 2A bound to TIPRL
分子名称: MANGANESE (II) ION, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, ...
著者Wu, C, Zheng, A, Li, J, Satyshur, K, Xing, Y.
登録日2017-06-01
公開日2018-01-17
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Methylation-regulated decommissioning of multimeric PP2A complexes.
Nat Commun, 8, 2017
5W3L
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BU of 5w3l by Molmil
CryoEM structure of rhinovirus B14 in complex with C5 Fab (4 degrees Celsius, molar ratio 1:3, full particle)
分子名称: C5 antibody variable heavy domain, C5 antibody variable light domain, viral protein 1, ...
著者Liu, Y, Dong, Y, Rossmann, M.G.
登録日2017-06-08
公開日2017-07-12
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (2.71 Å)
主引用文献Antibody-induced uncoating of human rhinovirus B14.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1N1I
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The structure of MSP-1(19) from Plasmodium knowlesi
分子名称: HISTIDINE, IMIDAZOLE, Merozoite surface protein-1
著者Garman, S.C, Simcoke, W.N, Stowers, A.W, Garboczi, D.N.
登録日2002-10-17
公開日2003-02-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the C-terminal domains of merozoite surface protein-1 from Plasmodium knowlesi reveals a novel histidine binding site
J.Biol.Chem., 278, 2003
1MQP
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THE CRYSTAL STRUCTURE OF ALPHA-D-GLUCURONIDASE FROM BACILLUS STEAROTHERMOPHILUS T-6
分子名称: GLYCEROL, alpha-D-glucuronidase
著者Golan, G, Shallom, D, Teplitsky, A, Zaide, G, Shulami, S, Baasov, T, Stojanoff, V, Thompson, A, Shoham, Y, Shoham, G.
登録日2002-09-17
公開日2003-09-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of Geobacillus stearothermophilus alpha-glucuronidase complexed with its substrate and products: mechanistic implications.
J.Biol.Chem., 279, 2004
5W1W
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Structure of the HLA-E-VMAPRTLVL/GF4 TCR complex
分子名称: Beta-2-microglobulin, GF4 T cell receptor alpha chain, GF4 T cell receptor beta chain, ...
著者Gras, S, Walpole, N, Farenc, C, Rossjohn, J.
登録日2017-06-05
公開日2017-10-04
最終更新日2018-01-03
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A conserved energetic footprint underpins recognition of human leukocyte antigen-E by two distinct alpha beta T cell receptors.
J. Biol. Chem., 292, 2017
5W3E
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CryoEM structure of rhinovirus B14 in complex with C5 Fab (33 degrees Celsius, molar ratio 1:3, full particle)
分子名称: C5 antibody variable heavy domain, C5 antibody variable light domain, viral protein 1, ...
著者Liu, Y, Dong, Y, Rossmann, M.G.
登録日2017-06-07
公開日2017-07-12
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (2.53 Å)
主引用文献Antibody-induced uncoating of human rhinovirus B14.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7SIM
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BU of 7sim by Molmil
Structure of positive allosteric modulator-free active human calcium-sensing receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Park, J, Zuo, H, Frangaj, A, Fu, Z, Yen, L.Y, Zhang, Z, Mosyak, L, Slavkovich, V.N, Liu, J, Ray, K.M, Cao, B, Vallese, F, Geng, Y, Chen, S, Grassucci, R, Dandey, V.P, Tan, Y.Z, Eng, E, Lee, Y, Kloss, B, Liu, Z, Hendrickson, W.A, Potter, C.S, Carragher, B, Graziano, J, Conigrave, A.D, Frank, J, Clarke, O.B, Fan, Q.R.
登録日2021-10-14
公開日2022-01-19
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Symmetric activation and modulation of the human calcium-sensing receptor.
Proc.Natl.Acad.Sci.USA, 118, 2021
5W4I
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BU of 5w4i by Molmil
X-ray crystallographic structure of a beta-hairpin peptide mimic derived from Abeta 16-36. Rigaku data set. (ORN)KLV(MEA)FAE(ORN)AIIGLMV.
分子名称: A-beta 17_36: ORN-LYS-LEU-VAL-MEA-PHE-ALA-GLU-ORN-ALA-ILE-ILE-GLY-LEU-MET-VAL, CHLORIDE ION, IODIDE ION
著者Kreutzer, A.G, McKnelly, K.J, Nowick, J.S.
登録日2017-06-11
公開日2017-11-22
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.026 Å)
主引用文献A Hexamer of a Peptide Derived from A beta 16-36.
Biochemistry, 56, 2017
5W65
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RNA polymerase I Initial Transcribing Complex State 2
分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ...
著者Han, Y, He, Y.
登録日2017-06-16
公開日2017-08-02
最終更新日2019-11-27
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structural mechanism of ATP-independent transcription initiation by RNA polymerase I.
Elife, 6, 2017
5W4J
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BU of 5w4j by Molmil
X-ray crystallographic structure of a beta-hairpin peptide mimic. (ORN)KLV(MEA)FAE(ORN)AIIGLMV.
分子名称: A-beta 17_36 peptide: ORN-LYS-VAL-PHE-MEA-ALA-ALA-ASP-ORN-ALA-ILE-ILE-GLY-LEU-MET-VAL
著者Kreutzer, A.G, Nowick, J.S.
登録日2017-06-11
公開日2017-11-22
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献A Hexamer of a Peptide Derived from A beta 16-36.
Biochemistry, 56, 2017
5W64
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RNA Polymerase I Initial Transcribing Complex State 1
分子名称: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ...
著者Han, Y, He, Y.
登録日2017-06-16
公開日2017-07-26
最終更新日2019-11-27
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural mechanism of ATP-independent transcription initiation by RNA polymerase I.
Elife, 6, 2017
7SIL
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BU of 7sil by Molmil
Structure of positive allosteric modulator-bound active human calcium-sensing receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(2-chlorophenyl)-N-[(1R)-1-(3-methoxyphenyl)ethyl]propan-1-amine, ...
著者Park, J, Zuo, H, Frangaj, A, Fu, Z, Yen, L.Y, Zhang, Z, Mosyak, L, Slavkovich, V.N, Liu, J, Ray, K.M, Cao, B, Vallese, F, Geng, Y, Chen, S, Grassucci, R, Dandey, V.P, Tan, Y.Z, Eng, E, Lee, Y, Kloss, B, Liu, Z, Hendrickson, W.A, Potter, C.S, Carragher, B, Graziano, J, Conigrave, A.D, Frank, J, Clarke, O.B, Fan, Q.R.
登録日2021-10-14
公開日2022-01-19
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Symmetric activation and modulation of the human calcium-sensing receptor.
Proc.Natl.Acad.Sci.USA, 118, 2021
4GMX
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BU of 4gmx by Molmil
Crystal structure of KPT185 in complex with CRM1-Ran-RanBP1
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ...
著者Sun, Q, Chook, Y.M.
登録日2012-08-16
公開日2012-10-17
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia.
Blood, 120, 2012
3CS0
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BU of 3cs0 by Molmil
Crystal structure of DegP24
分子名称: Periplasmic serine endoprotease DegP, pentapeptide
著者Krojer, T, Sawa, J, Schaefer, E, Saibil, H.R, Ehrmann, M, Clausen, T.
登録日2008-04-08
公開日2008-05-27
最終更新日2019-11-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for the regulated protease and chaperone function of DegP
Nature, 453, 2008
5WBS
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BU of 5wbs by Molmil
Crystal structure of Frizzled-7 CRD with an inhibitor peptide Fz7-21
分子名称: Frizzled-7,inhibitor peptide Fz7-21
著者Nile, A.H, Mukund, S, Hannoush, R.N, Wang, W.
登録日2017-06-29
公開日2018-04-18
最終更新日2018-05-30
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells.
Nat. Chem. Biol., 14, 2018
1MVF
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MazE addiction antidote
分子名称: PemI-like protein 1, immunoglobulin heavy chain variable region
著者Loris, R, Marianovsky, I, Lah, J, Laeremans, T, Engelberg-Kulka, H, Glaser, G, Muyldermans, S, Wyns, L.
登録日2002-09-25
公開日2003-06-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of the intrinsically flexible addiction antidote MazE.
J.Biol.Chem., 278, 2003
5WL2
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VH1-69 germline antibody with CDR H3 sequence of CR9114
分子名称: Germline-reverted light chain of CR9114, Heavy chain of VH1-69 germline antibody with CDR H3 sequence of CR9114
著者Wilson, I.A, Lang, S.
登録日2017-07-25
公開日2018-08-01
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Anti-idiotypic antibody K1-18 engages VH1-69 precursor and affinity-matured, anti-stem antibodies through mimicry of the HA stem.
To Be Published
3VDN
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BU of 3vdn by Molmil
Crystal Structure of VldE, the pseudo-glycosyltransferase, in complex with GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, VldE
著者Cavalier, M.C, Yim, Y.-S, Asamizu, S, Neau, D, Mahmud, T, Lee, Y.-H.
登録日2012-01-05
公開日2013-01-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal Structure of the VldE, the pseudo-glycosyltransferase, which catalyzes non-glycosidic C-N coupling in Validamycin A biosynthesis
To be Published
5WLL
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BU of 5wll by Molmil
De Novo Design of Polynuclear Transition Metal Clusters in Helix Bundles-4DH1
分子名称: GLYCEROL, Helical Bundle 4DH1, ZINC ION
著者Zhang, S.-Q, Liu, L, DeGrado, W.F.
登録日2017-07-27
公開日2018-01-03
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献De Novo Design of Tetranuclear Transition Metal Clusters Stabilized by Hydrogen-Bonded Networks in Helical Bundles.
J. Am. Chem. Soc., 140, 2018
1MVU
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SINGLE CHAIN FV OF C219 HEAVY CHAIN V101L MUTANT IN COMPLEX WITH SYNTHETIC EPITOPE PEPTIDE
分子名称: Ig VDJ-region (HEAVY CHAIN), Ig kappa-chain VJ-region (Light chain), P-GLYCOPROTEIN, ...
著者Chan, D.C.M, Kuntz, D.A, Rose, D.R.
登録日2002-09-26
公開日2003-10-07
最終更新日2013-09-18
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Single Chain C219 V(101H)L Mutant Antibody Complexed with a Helical Peptide
To be Published
3VE0
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BU of 3ve0 by Molmil
Crystal structure of Sudan Ebolavirus Glycoprotein (strain Boniface) bound to 16F6
分子名称: 16F6 Antibody chain A, 16F6 Antibody chain B, Envelope glycoprotein, ...
著者Saphire, E.O, Bale, S, Dias, J.M.
登録日2012-01-06
公開日2012-04-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.353 Å)
主引用文献Structural basis for differential neutralization of ebolaviruses.
Viruses, 4, 2012
1N0H
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Crystal Structure of Yeast Acetohydroxyacid Synthase in Complex with a Sulfonylurea Herbicide, Chlorimuron Ethyl
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-[[[[(4-CHLORO-6-METHOXY-2-PYRIMIDINYL)AMINO]CARBONYL]AMINO]SULFONYL]BENZOIC ACID ETHYL ESTER, 4-{[(4'-AMINO-2'-METHYLPYRIMIDIN-5'-YL)METHYL]AMINO}PENT-3-ENYL DIPHOSPHATE, ...
著者Pang, S.S, Guddat, L.W, Duggleby, R.G.
登録日2002-10-14
公開日2003-01-07
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular basis of sulfonylurea herbicide inhibition of acetohydroxyacid synthase
J.BIOL.CHEM., 278, 2003

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