PDB: 13258 件ウェブページステータス検索Chemie searchBIRD

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6HU1	Crystal structure of Schistosoma mansoni HDAC8 complexed with a benzohydroxamate inhibitor 10 分子名称: 4-chloranyl-3-[(2,4-dichlorophenyl)carbonylamino]-~{N}-oxidanyl-benzamide, DIMETHYLFORMAMIDE, GLYCEROL, ... 著者 Shaik, T.B, Marek, M, Romier, C. 登録日 2018-10-05 公開日 2018-10-31 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.996 Å) 主引用文献 Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants. J. Med. Chem., 61, 2018
6HU0	Crystal structure of Schistosoma mansoni HDAC8 complexed with a benzohydroxamate inhibitor 9 分子名称: 3-[(2,4-dichlorophenyl)carbonylamino]-4-methoxy-~{N}-oxidanyl-benzamide, DIMETHYLFORMAMIDE, GLYCEROL, ... 著者 Shaik, T.B, Marek, M, Romier, C. 登録日 2018-10-05 公開日 2018-10-31 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.746 Å) 主引用文献 Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants. J. Med. Chem., 61, 2018
1NK3	VND/NK-2 HOMEODOMAIN/DNA COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE 分子名称: DNA (5'-D(*AP*CP*AP*GP*CP*CP*AP*CP*TP*TP*GP*AP*CP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*GP*TP*CP*AP*AP*GP*TP*GP*GP*CP*TP*GP*T)-3'), HOMEOBOX PROTEIN VND 著者 Gruschus, J.M, Tsao, D.H.H, Wang, L.-H, Nirenberg, M, Ferretti, J.A. 登録日 1998-05-06 公開日 1998-12-09 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Interactions of the vnd/NK-2 homeodomain with DNA by nuclear magnetic resonance spectroscopy: basis of binding specificity. Biochemistry, 36, 1997
1NK2	VND/NK-2 HOMEODOMAIN/DNA COMPLEX, NMR, 20 STRUCTURES 分子名称: DNA (5'-D(*AP*CP*AP*GP*CP*CP*AP*CP*TP*TP*GP*AP*CP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*GP*TP*CP*AP*AP*GP*TP*GP*GP*CP*TP*GP*T)-3'), HOMEOBOX PROTEIN VND 著者 Gruschus, J.M, Tsao, D.H.H, Wang, L.-H, Nirenberg, M, Ferretti, J.A. 登録日 1998-05-06 公開日 1999-02-23 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Interactions of the vnd/NK-2 homeodomain with DNA by nuclear magnetic resonance spectroscopy: basis of binding specificity. Biochemistry, 36, 1997
6HG4	Crystal Structure of the human IL-17RC ECD in complex with human IL-17F 分子名称: Interleukin-17 receptor C, Interleukin-17F 著者 Rondeau, J.M, Goepfert, A. 登録日 2018-08-22 公開日 2020-03-18 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.32 Å) 主引用文献 Structural Analysis Reveals that the Cytokine IL-17F Forms a Homodimeric Complex with Receptor IL-17RC to Drive IL-17RA-Independent Signaling. Immunity, 52, 2020
6HTG	Crystal structure of Schistosoma mansoni HDAC8 complexed with a benzohydroxamate inhibitor 4 分子名称: 3-benzamido-4-chloranyl-~{N}-oxidanyl-benzamide, DIMETHYLFORMAMIDE, GLYCEROL, ... 著者 Shaik, T.B, Marek, M, Romier, C. 登録日 2018-10-04 公開日 2018-10-31 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.939 Å) 主引用文献 Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants. J. Med. Chem., 61, 2018
6HTZ	Crystal structure of Schistosoma mansoni HDAC8 complexed with a benzohydroxamate inhibitor 8 分子名称: 4-methoxy-~{N}-oxidanyl-3-(2-phenylethanoylamino)benzamide, DIMETHYLFORMAMIDE, GLYCEROL, ... 著者 Shaik, T.B, Marek, M, Romier, C. 登録日 2018-10-05 公開日 2018-10-31 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.841 Å) 主引用文献 Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants. J. Med. Chem., 61, 2018
3QAM	Crystal Structure of Glu208Ala mutant of catalytic subunit of cAMP-dependent protein kinase 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Protein kinase inhibitor, ... 著者 Yang, J, Wu, J, Steichen, J, Taylor, S.S. 登録日 2011-01-11 公開日 2011-12-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 A conserved Glu-Arg salt bridge connects coevolved motifs that define the eukaryotic protein kinase fold. J.Mol.Biol., 415, 2012
7UG1	CDK2 liganded with para chloro ANS 分子名称: 1,2-ETHANEDIOL, 8-(4-chloroanilino)naphthalene-1-sulfonic acid, Cyclin-dependent kinase 2, ... 著者 Schonbrunn, E, Martin, M. 登録日 2022-03-23 公開日 2023-04-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Allosteric inhibitors of CDK2 To Be Published
3I8D	The Pairing Geometry of the Hydrophobic Thymine Analog 2,4-Difluorotoluene in Duplex DNA as Analyzed by X-ray Crystallography 分子名称: 5'-D(*CP*GP*CP*GP*AP*AP*TP*(DFT)P*CP*GP*CP*G)-3', GLYCEROL, Ribonuclease H 著者 Egli, M, Pallan, P.S. 登録日 2009-07-09 公開日 2009-09-01 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Pairing geometry of the hydrophobic thymine analogue 2,4-difluorotoluene in duplex DNA as analyzed by X-ray crystallography. J.Am.Chem.Soc., 131, 2009
1LDK	Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF Ubiquitin Ligase Complex 分子名称: CULLIN HOMOLOG, CYCLIN A/CDK2-ASSOCIATED PROTEIN P19, SKP2-like protein type gamma, ... 著者 Zheng, N, Schulman, B.A, Song, L, Miller, J.J, Jeffrey, P.D, Wang, P, Chu, C, Koepp, D.M, Elledge, S.J, Pagano, M, Conaway, R.C, Conaway, J.W, Harper, J.W, Pavletich, N.P. 登録日 2002-04-08 公開日 2002-05-08 最終更新日 2019-11-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex. Nature, 416, 2002
6HSK	Crystal structure of a human HDAC8 L6 loop mutant complexed with Quisinostat 分子名称: 2-[4-[[(1-methylindol-3-yl)methylamino]methyl]piperidin-1-yl]-~{N}-oxidanyl-pyrimidine-5-carboxamide, Histone deacetylase 8, POTASSIUM ION, ... 著者 Marek, M, Shaik, T.B, Ramos-Morales, E, Romier, C. 登録日 2018-10-01 公開日 2018-10-31 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.096 Å) 主引用文献 Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants. J. Med. Chem., 61, 2018
6HSZ	Crystal structure of Schistosoma mansoni HDAC8 complexed with a benzohydroxamate inhibitor 2 分子名称: 3-benzamido-4-methyl-~{N}-oxidanyl-benzamide, GLYCEROL, Histone deacetylase, ... 著者 Marek, M, Shaik, T.B, Romier, C. 登録日 2018-10-02 公開日 2018-10-31 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.374 Å) 主引用文献 Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants. J. Med. Chem., 61, 2018
6HG9	Crystal Structure of the human IL-17RC ECD in complex with human IL-17F, Crystal form II 分子名称: Interleukin-17 receptor C, Interleukin-17F 著者 Rondeau, J.M, Goepfert, A. 登録日 2018-08-23 公開日 2020-03-18 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.62 Å) 主引用文献 Structural Analysis Reveals that the Cytokine IL-17F Forms a Homodimeric Complex with Receptor IL-17RC to Drive IL-17RA-Independent Signaling. Immunity, 52, 2020
3PQJ	Crystal Structure of the transcriptional repressor BigR from Xylella fastidiosa 分子名称: Biofilm growth-associated repressor 著者 Guimaraes, B.G, Benedetti, C.E. 登録日 2010-11-26 公開日 2011-06-01 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Plant Pathogenic Bacteria Utilize Biofilm Growth-associated Repressor (BigR), a Novel Winged-helix Redox Switch, to Control Hydrogen Sulfide Detoxification under Hypoxia. J.Biol.Chem., 286, 2011
7V3U	Cryo-EM structure of MCM double hexamer with structured Mcm4-NSD 分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, ... 著者 Cheng, J, Li, N, Huo, Y, Dang, S, Tye, B, Gao, N, Zhai, Y. 登録日 2021-08-11 公開日 2022-04-13 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural Insight into the MCM double hexamer activation by Dbf4-Cdc7 kinase. Nat Commun, 13, 2022
7V3V	Cryo-EM structure of MCM double hexamer bound with DDK in State I 分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 7, DDK kinase regulatory subunit DBF4, ... 著者 Cheng, J, Li, N, Huo, Y, Dang, S, Tye, B, Gao, N, Zhai, Y. 登録日 2021-08-11 公開日 2022-04-13 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural Insight into the MCM double hexamer activation by Dbf4-Cdc7 kinase. Nat Commun, 13, 2022
1M1G	Crystal Structure of Aquifex aeolicus N-utilization substance G (NusG), Space Group P2(1) 分子名称: Transcription antitermination protein nusG 著者 Steiner, T, Kaiser, J.T, Marinkovic, S, Huber, R, Wahl, M.C. 登録日 2002-06-19 公開日 2003-02-04 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structures of transcription factor NusG in light of its nucleic acid- and protein-binding activities Embo J., 21, 2002
7EL2	Crystal structure of apo-HpaR from Acinetobacter baumannii 分子名称: Homoprotocatechuate degradation operon regulator HpaR 著者 Permsirivisarn, P, Pakotiprapha, D. 登録日 2021-04-07 公開日 2022-01-19 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Mechanism of transcription regulation by Acinetobacter baumannii HpaR in the catabolism of p-hydroxyphenylacetate. Febs J., 289, 2022
7EL3	Crystal structure of HpaR-DNA complex from Acinetobacter baumannii 分子名称: Chains: C, Chains: D, GLYCEROL, ... 著者 Permsirivisarn, P, Pakotiprapha, D. 登録日 2021-04-07 公開日 2022-01-19 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Mechanism of transcription regulation by Acinetobacter baumannii HpaR in the catabolism of p-hydroxyphenylacetate. Febs J., 289, 2022
6K0C	Crystal structure of ceNAP1-H2A.Z-H2B complex 分子名称: Histone H2B 2,Histone H2A.V, Nucleosome Assembly Protein 著者 Liu, Y.R. 登録日 2019-05-05 公開日 2019-10-09 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.281 Å) 主引用文献 Crystal structure of xlH2A-H2B Structure, 2019
6INL	Crystal structure of CDK2 IN complex with Inhibitor CVT-313 分子名称: 2,2'-{[6-{[(4-methoxyphenyl)methyl]amino}-9-(propan-2-yl)-9H-purin-2-yl]azanediyl}di(ethan-1-ol), Cyclin-dependent kinase 2 著者 Talapati, S.R, Krishnamurthy, N.R. 登録日 2018-10-25 公開日 2019-10-30 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure of cyclin-dependent kinase 2 (CDK2) in complex with the specific and potent inhibitor CVT-313. Acta Crystallogr.,Sect.F, 76, 2020
1NYT	SHIKIMATE DEHYDROGENASE AroE COMPLEXED WITH NADP+ 分子名称: (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ... 著者 Roszak, A.W, Lapthorn, A.J. 登録日 2003-02-13 公開日 2003-03-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structures of shikimate dehydrogenase AroE and its Paralog YdiB. A common structural framework for different activities. J.Biol.Chem., 278, 2003
1NOU	Native human lysosomal beta-hexosaminidase isoform B 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, SULFATE ION, ... 著者 Mark, B.L, Mahuran, D.J, Cherney, M.M, Zhao, D, Knapp, S, James, M.N.G. 登録日 2003-01-16 公開日 2003-04-08 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of Human beta-hexosaminidase B: Understanding the molecular basis of Sandhoff and Tay-Sachs disease J.Mol.Biol., 327, 2003
1OCP	SOLUTION STRUCTURE OF OCT3 POU-HOMEODOMAIN 分子名称: OCT-3 著者 Morita, E.H, Hayashi, F, Shirakawa, M, Kyogoku, Y. 登録日 1995-02-21 公開日 1995-09-15 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure of the Oct-3 POU-Homeodomain in Solution, as Determined by Triple Resonance Heteronuclear Multidimensional NMR Spectroscopy Protein Sci., 4, 1995

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