PDB: 184050 件ウェブページステータス検索Chemie searchBIRD

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7JMM	Crystal structure of the substrate-binding domain of E. coli DnaK in complex with the peptide RAKNIILLSR 分子名称: Alkaline phosphatase, Chaperone protein DnaK, SULFATE ION 著者 Jansen, R.M, Ozden, C, Gierasch, L.M, Garman, S.C. 登録日 2020-08-02 公開日 2020-08-26 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Selective promiscuity in the binding of E. coli Hsp70 to an unfolded protein. Proc.Natl.Acad.Sci.USA, 118, 2021
4GSX	High resolution structure of dengue virus serotype 1 sE containing stem 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, CHLORIDE ION, ... 著者 Klein, D.E, Choi, J.L, Harrison, S.C. 登録日 2012-08-28 公開日 2012-12-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.903 Å) 主引用文献 Structure of a dengue virus envelope protein late-stage fusion intermediate. J.Virol., 87, 2013
1KE6	CYCLIN-DEPENDENT KINASE 2 (CDK2) COMPLEXED WITH N-METHYL-{4-[2-(7-OXO-6,7-DIHYDRO-8H-[1,3]THIAZOLO[5,4-E]INDOL-8-YLIDENE)HYDRAZINO]PHENYL}METHANESULFONAMIDE 分子名称: Cell division protein kinase 2, N-METHYL-{4-[2-(7-OXO-6,7-DIHYDRO-8H-[1,3]THIAZOLO[5,4-E]INDOL-8-YLIDENE)HYDRAZINO]PHENYL}METHANESULFONAMIDE 著者 Bramson, H.N, Corona, J, Davis, S.T, Dickerson, S.H, Edelstein, M, Frye, S.V, Gampe, R.T, Hassell, A.H, Shewchuk, L.M, Kuyper, L.F. 登録日 2001-11-14 公開日 2002-05-14 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Oxindole-based inhibitors of cyclin-dependent kinase 2 (CDK2): design, synthesis, enzymatic activities, and X-ray crystallographic analysis. J.Med.Chem., 44, 2001
4Q6D	Crystal structure of human carbonic anhydrase isozyme II with 4-[(Z)-azepan-1-yldiazenyl]benzenesulfonamide 分子名称: 4-[(E)-azepan-1-yldiazenyl]benzenesulfonamide, BICINE, Carbonic anhydrase 2, ... 著者 Smirnov, A, Manakova, E, Grazulis, S. 登録日 2014-04-22 公開日 2014-11-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 4-Amino-substituted Benzenesulfonamides as Inhibitors of Human Carbonic Anhydrases. Molecules, 19, 2014
5NAL	The crystal structure of inhibitor-15 covalently bound to PDE6D 分子名称: Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, ~{N}4-[(4-chlorophenyl)methyl]-~{N}1-(cyclohexylmethyl)-~{N}4-cyclopentyl-~{N}1-[(~{Z})-4-[(~{E})-methyliminomethyl]-5-oxidanyl-hex-4-enyl]benzene-1,4-disulfonamide 著者 Fansa, E.K, Martin-Gago, P, Waldmann, H, Wittinghofer, A. 登録日 2017-02-28 公開日 2017-05-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Covalent Protein Labeling at Glutamic Acids. Cell Chem Biol, 24, 2017
3MEG	HIV-1 K103N Reverse Transcriptase in Complex with TMC278 分子名称: 4-{[4-({4-[(E)-2-cyanoethenyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile, SULFATE ION, p51 Reverse transcriptase, ... 著者 Lansdon, E.B. 登録日 2010-03-31 公開日 2010-05-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal Structures of HIV-1 Reverse Transcriptase with Etravirine (TMC125) and Rilpivirine (TMC278): Implications for Drug Design. J.Med.Chem., 53, 2010
1TUG	Aspartate Transcarbamoylase Catalytic Chain Mutant E50A Complex with Phosphonoacetamide, Malonate, and Cytidine-5-Prime-Triphosphate (CTP) 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... 著者 Stieglitz, K, Stec, B, Baker, D.P, Kantrowitz, E.R. 登録日 2004-06-24 公開日 2004-07-20 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Monitoring the Transition from the T to the R State in E.coli Aspartate Transcarbamoylase by X-ray Crystallography: Crystal Structures of the E50A Mutant Enzyme in Four Distinct Allosteric States. J.Mol.Biol., 341, 2004
1TTH	Aspartate Transcarbamoylase Catalytic Chain Mutant Glu50Ala Complexed with N-(Phosphonacetyl-L-Aspartate) (PALA) 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, ... 著者 Stieglitz, K, Stec, B, Baker, D.P, Kantrowitz, E.R. 登録日 2004-06-22 公開日 2004-07-20 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Monitoring the Transition from the T to the R State in E.coli Aspartate Transcarbamoylase by X-ray Crystallography: Crystal Structures of the E50A Mutant Enzyme in Four Distinct Allosteric States. J.Mol.Biol., 341, 2004
7DYQ	Crystal structure of histone lysine demethylase 4D (KDM4D) in complex with the inhibitor 5-hydroxy-2-methylpyrazolo[1,5-a]pyrido[3,2-e]pyrimidine-3-carbonitrile 分子名称: 5-hydroxy-2-methylpyrazolo[1,5-a]pyrido[3,2-e]pyrimidine-3-carbonitrile, FE (III) ION, Lysine-specific demethylase 4D 著者 Wang, T, Yang, L. 登録日 2021-01-22 公開日 2022-01-26 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.998 Å) 主引用文献 Crystal structure of histone lysine demethylase 4D (KDM4D) in complex with the inhibitor 5-hydroxy-2-methylpyrazolo[1,5-a]pyrido[3,2-e]pyrimidine-3-carbonitrile To Be Published
3BDW	Human CD94/NKG2A 分子名称: NKG2-A/NKG2-B type II integral membrane protein, Natural killer cells antigen CD94 著者 Sullivan, L.C, Clements, C.S. 登録日 2007-11-15 公開日 2008-01-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The Heterodimeric Assembly of the CD94-NKG2 Receptor Family and Implications for Human Leukocyte Antigen-E Recognition Immunity, 27, 2007
4HJU	Transthyretin in complex with (E)-N-(3-(4-hydroxy-3,5-dimethylstyryl)phenyl)acrylamide 分子名称: N-{3-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]phenyl}prop-2-enamide, Transthyretin 著者 Connelly, S, Wilson, I.A. 登録日 2012-10-14 公開日 2013-12-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Stilbene vinyl sulfonamides as fluorogenic sensors of and traceless covalent kinetic stabilizers of transthyretin that prevent amyloidogenesis. J.Am.Chem.Soc., 135, 2013
3N7O	X-ray structure of human chymase in complex with small molecule inhibitor. 分子名称: (S)-[(1S)-1-(5-chloro-1-benzothiophen-3-yl)-2-{[(E)-2-(3,4-difluorophenyl)ethenyl]amino}-2-oxoethyl]methylphosphinic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chymase, ... 著者 Abad, M.C, Kervinen, J, Crysler, C, Bayoumy, S, Spurlino, J, Deckman, I, Greco, M.N, Maryanoff, B.E, Degaravilla, L. 登録日 2010-05-27 公開日 2010-07-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Potency variation of small-molecule chymase inhibitors across species. Biochem. Pharmacol., 80, 2010
1G1T	CRYSTAL STRUCTURE OF E-SELECTIN LECTIN/EGF DOMAINS COMPLEXED WITH SLEX 分子名称: CALCIUM ION, E-SELECTIN, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]methyl 2-acetamido-2-deoxy-beta-D-glucopyranoside 著者 Somers, W.S, Camphausen, R.T. 登録日 2000-10-13 公開日 2001-10-13 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Insights into the molecular basis of leukocyte tethering and rolling revealed by structures of P- and E-selectin bound to SLe(X) and PSGL-1. Cell(Cambridge,Mass.), 103, 2000
1Y6V	Structure of E. coli Alkaline Phosphatase in presence of cobalt at 1.60 A resolution 分子名称: Alkaline phosphatase, COBALT (II) ION, PHOSPHATE ION, ... 著者 Wang, J, Stieglitz, K, Kantrowitz, E.R. 登録日 2004-12-07 公開日 2005-06-21 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Metal Specificity Is Correlated with Two Crucial Active Site Residues in Escherichia coli Alkaline Phosphatase(,). Biochemistry, 44, 2005
3WHI	Crystal structure of unautoprocessed form of IS1-inserted Pro-subtilisin E 分子名称: CALCIUM ION, Subtilisin E 著者 Uehara, R, Angkawidjaja, C, Koga, Y, Kanaya, S. 登録日 2013-08-26 公開日 2013-12-25 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Formation of the High-Affinity Calcium Binding Site in Pro-subtilisin E with the Insertion Sequence IS1 of Pro-Tk-subtilisin Biochemistry, 52, 2013
2AWQ	Solution Structure of pseudouridine-32 modified anticodon stem-loop of E. coli tRNAPhe 分子名称: 5'-R(*GP*GP*GP*GP*AP*(PSU)P*UP*GP*AP*AP*AP*AP*UP*CP*CP*CP*C)-3' 著者 Cabello-Villegas, J, Nikonowicz, E.P. 登録日 2005-09-01 公開日 2006-01-17 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of psi32-modified anticodon stem-loop of Escherichia coli tRNAPhe. Nucleic Acids Res., 33, 2005
1TU0	Aspartate Transcarbamoylase Catalytic Chain Mutant E50A Complex with Phosphonoacetamide 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, PHOSPHONOACETAMIDE, ... 著者 Stieglitz, K, Stec, B, Baker, D.P, Kantrowitz, E.R. 登録日 2004-06-23 公開日 2004-07-20 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Monitoring the Transition from the T to the R State in E.coli Aspartate Transcarbamoylase by X-ray Crystallography: Crystal Structures of the E50A Mutant Enzyme in Four Distinct Allosteric States. J.Mol.Biol., 341, 2004
1PS6	Crystal structure of E.coli PdxA 分子名称: 4-HYDROXY-L-THREONINE-5-MONOPHOSPHATE, 4-hydroxythreonine-4-phosphate dehydrogenase, ZINC ION 著者 Sivaraman, J, Li, Y, Banks, J, Cane, D.E, Matte, A, Cygler, M. 登録日 2003-06-20 公開日 2003-11-04 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal Structure of Escherichia coli PdxA, an Enzyme Involved in the Pyridoxal Phosphate Biosynthesis Pathway J.Biol.Chem., 278, 2003
2WKX	Crystal structure of the native E. coli zinc amidase AmiD 分子名称: CHLORIDE ION, GLYCEROL, N-ACETYLMURAMOYL-L-ALANINE AMIDASE AMID, ... 著者 Petrella, S, Kerff, F, Herman, R, Genereux, C, Pennartz, A, Sauvage, E, Joris, B, Charlier, P. 登録日 2009-06-18 公開日 2010-01-12 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Specific Structural Features of the N-Acetylmuramoyl-L-Alanine Amidase Amid from Escherichia Coli and Mechanistic Implications for Enzymes of This Family. J.Mol.Biol., 397, 2010
1TOI	Hydrocinnamic acid-bound structure of Hexamutant + A293D mutant of E. coli aspartate aminotransferase 分子名称: Aspartate aminotransferase, HYDROCINNAMIC ACID 著者 Chow, M.A, McElroy, K.E, Corbett, K.D, Berger, J.M, Kirsch, J.F. 登録日 2004-06-14 公開日 2004-10-05 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Narrowing substrate specificity in a directly evolved enzyme: the A293D mutant of aspartate aminotransferase Biochemistry, 43, 2004
3JZ1	Crystal structure of human thrombin mutant N143P in E:Na+ form 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, NITRATE ION, ... 著者 Niu, W, Chen, Z, Bush-Pelc, L.A, Bah, A, Gandhi, P.S, Di Cera, E. 登録日 2009-09-22 公開日 2009-10-20 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Mutant N143P reveals how Na+ activates thrombin J.Biol.Chem., 284, 2009
1PTM	Crystal structure of E.coli PdxA 分子名称: 4-hydroxythreonine-4-phosphate dehydrogenase, PHOSPHATE ION, ZINC ION 著者 Sivaraman, J, Li, Y, Banks, J, Cane, D.E, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) 登録日 2003-06-23 公開日 2003-11-04 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Crystal Structure of Escherichia coli PdxA, an Enzyme Involved in the Pyridoxal Phosphate Biosynthesis Pathway J.Biol.Chem., 278, 2003
1GKS	ECTOTHIORHODOSPIRA HALOPHILA CYTOCHROME C551 (REDUCED), NMR, 37 STRUCTURES 分子名称: CYTOCHROME C551, PROTOPORPHYRIN IX CONTAINING FE 著者 Bersch, B, Blackledge, M.J, Meyer, T.E, Marion, D. 登録日 1996-07-16 公開日 1997-01-27 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 Ectothiorhodospira halophila ferrocytochrome c551: solution structure and comparison with bacterial cytochromes c. J.Mol.Biol., 264, 1996
4P6F	Crystal structure of the peptolide 12C bound to bacterial ribosome 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Fagan, C.E, Dunham, C.M. 登録日 2014-03-24 公開日 2014-10-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Macrolide-Peptide Conjugates as Probes of the Path of Travel of the Nascent Peptides through the Ribosome. Acs Chem.Biol., 9, 2014
1OO6	Nitroreductase from e-coli in complex with the dinitrobenzamide prodrug SN23862 分子名称: 5-[BIS-2(CHLORO-ETHYL)-AMINO]-2,4-DINTRO-BENZAMIDE, FLAVIN MONONUCLEOTIDE, Oxygen-insensitive NAD(P)H nitroreductase 著者 Johansson, E, Parkinson, G.N, Denny, W.A, Neidle, S. 登録日 2003-03-03 公開日 2003-04-08 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Studies on the Nitroreductase Prodrug-Activating System. Crystal Structures of Complexes with the Inhibitor Dicoumarol and Dinitrobenzamide Prodrugs and of the Enzyme Active Form J.Med.Chem., 46, 2003

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