2ESV
Structure of the HLA-E-VMAPRTLIL/KK50.4 TCR complex
Summary for 2ESV
Entry DOI | 10.2210/pdb2esv/pdb |
Descriptor | HLA class I histocompatibility antigen, alpha chain E, Beta-2-microglobulin, VMAPRTLIL peptide from CMV gpUL40, ... (7 entities in total) |
Functional Keywords | t cell receptor, tcr, hla-e, cmv, pmhc-tcr complex, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P13747 Secreted: P61769 Membrane; Single-pass membrane protein (Potential): P01848 P01850 |
Total number of polymer chains | 5 |
Total formula weight | 94899.38 |
Authors | Hoare, H.L.,Rossjohn, J. (deposition date: 2005-10-27, release date: 2006-03-21, Last modification date: 2011-07-13) |
Primary citation | Hoare, H.L.,Sullivan, L.C.,Pietra, G.,Clements, C.S.,Lee, E.J.,Ely, L.K.,Beddoe, T.,Falco, M.,Kjer-Nielsen, L.,Reid, H.H.,McCluskey, J.,Moretta, L.,Rossjohn, J.,Brooks, A.G. Structural basis for a major histocompatibility complex class Ib-restricted T cell response Nat.Immunol., 7:256-264, 2006 Cited by PubMed: 16474394DOI: 10.1038/ni1312 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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