2ESV
Structure of the HLA-E-VMAPRTLIL/KK50.4 TCR complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA class I histocompatibility antigen, alpha chain E | polymer | 275 | 31867.1 | 1 | UniProt (P13747) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (human) | HLA-E*103, MHC class I antigen E |
| 2 | B (B) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | |
| 3 | C (P) | VMAPRTLIL peptide from CMV gpUL40 | polymer | 9 | 1014.3 | 1 | UniProt (by SIFTS) (P16780) | HLA-Cw3 leader sequence fragment | |
| 4 | D (D) | KK50.4 T cell receptor alpha chain | polymer | 199 | 22221.7 | 1 | UniProt (P01848) Pfam (PF09291) | Homo sapiens (human) | |
| 5 | E (E) | KK50.4 T cell receptor beta chain | polymer | 240 | 27282.4 | 1 | UniProt (P01850) Pfam (PF07654) | Homo sapiens (human) | |
| 6 | F, G, H, I, J (B, D, E) | IODIDE ION | non-polymer | 126.9 | 5 | Chemie (IOD) | |||
| 7 | K, L, M, N, O (A, B, P, D, E) | water | water | 18.0 | 185 | Chemie (HOH) |
Sequence modifications
B: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 94264.9 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 634.5 | |
| All* | Total formula weight | 94899.4 |
