1CRZ

CRYSTAL STRUCTURE OF THE E. COLI TOLB PROTEIN

Summary for 1CRZ

• Entry DOI: 10.2210/pdb1crz/pdb
• Descriptor: TOLB PROTEIN (2 entities in total)
• Functional Keywords: two domains: beta propeller and alpha/beta fold, toxin binding protein
• Biological source: Escherichia coli
• Cellular location: Periplasm : P0A855
• Total number of polymer chains: 1
• Total formula weight: 43207.86

Authors

Abergel, C.,Bouveret, E.,Claverie, J.-M.,Brown, K.,Rigal, A.,Lazdunski, C.,Benedetti, H. (deposition date: 1999-08-16, release date: 2000-08-16, Last modification date: 2024-10-09)

Primary citation

Abergel, C.,Bouveret, E.,Claverie, J.M.,Brown, K.,Rigal, A.,Lazdunski, C.,Benedetti, H.
Structure of the Escherichia coli TolB protein determined by MAD methods at 1.95 A resolution.
Structure Fold.Des., 7:1291-1300, 1999

PubMed Abstract: The periplasmic protein TolB from Escherichia coli is part of the Tol-PAL (peptidoglycan-associated lipoprotein) multiprotein complex used by group A colicins to penetrate and kill cells. TolB homologues are found in many gram-negative bacteria and the Tol-PAL system is thought to play a role in bacterial envelope integrity. TolB is required for lethal infection by Salmonella typhimurium in mice.

PubMed: 10545334
DOI: 10.1016/S0969-2126(00)80062-3

Experimental method

X-RAY DIFFRACTION (1.95 Å)