1NC1

Crystal structure of E. coli MTA/AdoHcy nucleosidase complexed with 5'-methylthiotubercidin (MTH)

Summary for 1NC1

Entry DOI	10.2210/pdb1nc1/pdb
Related	1JYS
Descriptor	MTA/SAH nucleosidase, 2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-METHYLSULFANYLMETHYL-TETRAHYDRO-FURAN-3,4-DIOL (3 entities in total)
Functional Keywords	mixed alpha/beta dimer, hydrolase
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	51568.94
Authors	Lee, J.E.,Cornell, K.A.,Riscoe, M.K.,Howell, P.L. (deposition date: 2002-12-04, release date: 2003-11-25, Last modification date: 2023-08-16)
Primary citation	Lee, J.E.,Cornell, K.A.,Riscoe, M.K.,Howell, P.L. Structure of Escherichia coli 5'-methylthioadenosine/ S-adenosylhomocysteine nucleosidase inhibitor complexes provide insight into the conformational changes required for substrate binding and catalysis. J.Biol.Chem., 278:8761-8770, 2003 Cited by PubMed: 12496243 DOI: 10.1074/jbc.M210836200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation