4RJY

Crystal structure of E. coli L-Threonine Aldolase in complex with a non-covalently uncleaved bound L-serine substrate

Summary for 4RJY

Entry DOI	10.2210/pdb4rjy/pdb
Descriptor	Low specificity L-threonine aldolase, SODIUM ION, SERINE, ... (4 entities in total)
Functional Keywords	pyridoxal-5-phosphate, threonine aldolase, aldimine, catalytic mechanism, retro-aldol cleavage, plp-dependent enzymes, lyase
Biological source	Escherichia coli
Total number of polymer chains	4
Total formula weight	147585.84
Authors	Safo, M.K.,Chowdhury, N.,Gandhi, A.K. (deposition date: 2014-10-11, release date: 2014-10-29, Last modification date: 2015-02-04)
Primary citation	Remesh, S.G.,Ghatge, M.S.,Ahmed, M.H.,Musayev, F.N.,Gandhi, A.,Chowdhury, N.,di Salvo, M.L.,Kellogg, G.E.,Contestabile, R.,Schirch, V.,Safo, M.K. Molecular basis of E. colil-threonine aldolase catalytic inactivation at low pH. Biochim.Biophys.Acta, 1854:278-283, 2015 Cited by PubMed: 25560296 DOI: 10.1016/j.bbapap.2014.12.023 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation