4W94
 
 | | Crystal structure of cross-linked tetragonal hen egg white lysozyme soaked with 5mM [Ru(CO)3Cl2]2 | | 分子名称: | CHLORIDE ION, DIMETHYLFORMAMIDE, Lysozyme C, ... | | 著者 | Tabe, H, Fujita, K, Abe, S, Tsujimoto, M, Kuchimaru, T, Kizaka-Kondo, S, Takano, M, Kitagawa, S, Ueno, T. | | 登録日 | 2014-08-27 | | 公開日 | 2014-12-31 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Preparation of a Cross-Linked Porous Protein Crystal Containing Ru Carbonyl Complexes as a CO-Releasing Extracellular Scaffold
Inorg.Chem., 54, 2015
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8HI5
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2RJX
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4W98
 | | Acinetobacter baumannii SDF NDK | | 分子名称: | Nucleoside diphosphate kinase | | 著者 | Hu, Y, Feng, F, Liang, H, Liu, Y. | | 登録日 | 2014-08-27 | | 公開日 | 2015-06-17 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | Structural and Functional Characterization of Acinetobacter baumannii Nucleoside Diphosphate Kinase
Prog.Biochem.Biophys., 42, 2015
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2RK3
 | | Structure of A104T DJ-1 | | 分子名称: | Protein DJ-1 | | 著者 | Lakshminarasimhan, M, Maldonado, M.T, Zhou, W, Fink, A.L, Wilson, M.A. | | 登録日 | 2007-10-16 | | 公開日 | 2008-01-15 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Structural Impact of Three Parkinsonism-Associated Missense Mutations on Human DJ-1.
Biochemistry, 47, 2008
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2RP4
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4W9E
 | | pVHL:EloB:EloC in complex with (2S,4R)-1-(3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(thiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (ligand 4) | | 分子名称: | (4R)-1-(3,3-dimethylbutanoyl)-4-hydroxy-N-[4-(1,3-thiazol-5-yl)benzyl]-L-prolinamide, Transcription elongation factor B polypeptide 1, Transcription elongation factor B polypeptide 2, ... | | 著者 | Gadd, M.S, Soares, P, Galdeano, C, van Molle, I, Ciulli, A. | | 登録日 | 2014-08-27 | | 公開日 | 2014-09-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure-Guided Design and Optimization of Small Molecules Targeting the Protein-Protein Interaction between the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase and the Hypoxia Inducible Factor (HIF) Alpha Subunit with in Vitro Nanomolar Affinities.
J.Med.Chem., 57, 2014
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8HKC
 | | Cryo-EM structure of E. coli RNAP sigma32 complex | | 分子名称: | DNA (54-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Wu, S, Ma, L.X. | | 登録日 | 2022-11-25 | | 公開日 | 2023-05-31 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.49 Å) | | 主引用文献 | Structural Insight into the Mechanism of sigma 32-Mediated Transcription Initiation of Bacterial RNA Polymerase.
Biomolecules, 13, 2023
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8HCN
 | | CryoEM Structure of Klebsiella pneumoniae UreD/urease complex | | 分子名称: | Urease accessory protein UreD, Urease subunit alpha, Urease subunit beta, ... | | 著者 | Nim, Y.S, Fong, I.Y.H, Deme, J, Tsang, K.L, Caesar, J, Johnson, S, Wong, K.B, Lea, S.M. | | 登録日 | 2022-11-02 | | 公開日 | 2023-05-03 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Delivering a toxic metal to the active site of urease.
Sci Adv, 9, 2023
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2RR0
 | | Structure of epidermal growth factor-like repeat 12 of mouse Notch-1 receptor | | 分子名称: | Neurogenic locus notch homolog protein 1 | | 著者 | Hosoguchi, K, Shimizu, K, Fujitani, N, Nishimura, S. | | 登録日 | 2010-02-26 | | 公開日 | 2010-10-13 | | 最終更新日 | 2024-10-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Chemical Synthesis, Folding, and Structural Insights into O-Fucosylated Epidermal Growth Factor-like Repeat 12 of Mouse Notch-1 Receptor
J.Am.Chem.Soc., 132, 2010
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4V7D
 | | Structure of the Ribosome with Elongation Factor G Trapped in the Pre-Translocation State (pre-translocation 70S*tRNA*EF-G structure) | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Brilot, A.F, Korostelev, A.A, Ermolenko, D.N, Grigorieff, N. | | 登録日 | 2013-11-21 | | 公開日 | 2014-07-09 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (7.6 Å) | | 主引用文献 | Structure of the ribosome with elongation factor G trapped in the pretranslocation state.
Proc.Natl.Acad.Sci.USA, 110, 2013
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8HAH
 | | Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 2 (3.9 angstrom resolution) | | 分子名称: | DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. | | 登録日 | 2022-10-26 | | 公開日 | 2023-05-17 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Epigenetic mechanisms to propagate histone acetylation by p300/CBP.
Nat Commun, 14, 2023
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2RR9
 | | The solution structure of the K63-Ub2:tUIMs complex | | 分子名称: | Putative uncharacterized protein UIMC1, ubiquitin | | 著者 | Sekiyama, N, Jee, J, Isogai, S, Akagi, K, Huang, T, Ariyoshi, M, Tochio, H, Shirakawa, M. | | 登録日 | 2010-06-16 | | 公開日 | 2011-07-06 | | 最終更新日 | 2011-07-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure of the K63-Ub2:tUIMs complex
To be Published
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4W9P
 | | The Fk1 domain of FKBP51 in complex with (1S,5S,6R)-10-[(3,5-dichlorophenyl)sulfonyl]-5-[(1S)-1,2-dihydroxyethyl]-3-[2-(3,4-dimethoxyphenoxy)ethyl]-3,10-diazabicyclo[4.3.1]decan-2-one | | 分子名称: | (1S,5S,6R)-10-[(3,5-dichlorophenyl)sulfonyl]-5-[(1S)-1,2-dihydroxyethyl]-3-[2-(3,4-dimethoxyphenoxy)ethyl]-3,10-diazabicyclo[4.3.1]decan-2-one, ACETATE ION, Peptidyl-prolyl cis-trans isomerase FKBP5 | | 著者 | Pomplun, S, Wang, Y, Kirschner, K, Kozany, C, Bracher, A, Hausch, F. | | 登録日 | 2014-08-27 | | 公開日 | 2014-12-03 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Rational Design and Asymmetric Synthesis of Potent and Neurotrophic Ligands for FK506-Binding Proteins (FKBPs).
Angew.Chem.Int.Ed.Engl., 54, 2015
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4W9W
 | | Crystal Structure of BMP-2-inducible kinase in complex with small molecule AZD-7762 | | 分子名称: | 1,2-ETHANEDIOL, 5-(3-fluorophenyl)-N-[(3S)-3-piperidyl]-3-ureido-thiophene-2-carboxamide, BMP-2-inducible protein kinase | | 著者 | Sorrell, F.J, Elkins, J.M, Krojer, T, Savitsky, P, Williams, E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2014-08-28 | | 公開日 | 2014-09-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Family-wide Structural Analysis of Human Numb-Associated Protein Kinases.
Structure, 24, 2016
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8HDJ
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2RTT
 | | Solution structure of the chitin-binding domain of Chi18aC from Streptomyces coelicolor | | 分子名称: | ChiC | | 著者 | Okumura, A, Uemura, M, Yamada, N, Chikaishi, E, Takai, T, Yoshio, S, Akagi, K, Morita, J, Lee, Y, Yokogawa, D, Suzuki, K, Watanabe, T, Ikegami, T. | | 登録日 | 2013-08-26 | | 公開日 | 2014-08-27 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the Chitin-binding domain of chitinase Chi18aC from Streptomyces coelicolor
To be Published
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4WA6
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8HJE
 | | Vismodegib binds to the catalytical domain of human Ubiquitin-Specific Protease 28 | | 分子名称: | 2-chloranyl-~{N}-(4-chloranyl-3-pyridin-2-yl-phenyl)-4-methylsulfonyl-benzamide, Ubiquitin carboxyl-terminal hydrolase 28 | | 著者 | Shi, L, Wang, H, Xu, Z, Xiong, B, Zhang, N. | | 登録日 | 2022-11-23 | | 公開日 | 2023-05-03 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structure-based discovery of potent USP28 inhibitors derived from Vismodegib.
Eur.J.Med.Chem., 254, 2023
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2RKG
 | | HIV-1 PR resistant mutant + LPV | | 分子名称: | GLYCEROL, N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE, PROTEASE RETROPEPSIN | | 著者 | Rezacova, P, Brynda, J, Kozisek, M, Saskova, K, Konvalinka, J. | | 登録日 | 2007-10-16 | | 公開日 | 2008-08-05 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Ninety-nine is not enough: molecular characterization of inhibitor-resistant human immunodeficiency virus type 1 protease mutants with insertions in the flap region
J.Virol., 82, 2008
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8H6D
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4WB3
 | | Crystal structure of the mirror-image L-RNA/L-DNA aptamer NOX-D20 in complex with mouse C5a-desArg complement anaphylatoxin | | 分子名称: | ACETATE ION, CALCIUM ION, Complement C5, ... | | 著者 | Yatime, L, Maasch, C, Hoehlig, K, Klussmann, S, Vater, A, Andersen, G.R. | | 登録日 | 2014-09-02 | | 公開日 | 2015-05-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis for the targeting of complement anaphylatoxin C5a using a mixed L-RNA/L-DNA aptamer.
Nat Commun, 6, 2015
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8H08
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2RUW
 | | Solution structures of the DNA-binding domain (ZF5) of immune-related zinc-finger protein ZFAT | | 分子名称: | ZINC ION, Zinc finger protein ZFAT | | 著者 | Tochio, N, Umehara, T, Kigawa, T, Yokoyama, S. | | 登録日 | 2015-01-26 | | 公開日 | 2015-04-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT
J.Struct.Funct.Genom., 16, 2015
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8HAI
 | | Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 1 (4.7 angstrom resolution) | | 分子名称: | DNA (180-mer), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. | | 登録日 | 2022-10-26 | | 公開日 | 2023-05-17 | | 最終更新日 | 2023-07-26 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | Epigenetic mechanisms to propagate histone acetylation by p300/CBP.
Nat Commun, 14, 2023
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