8HAI

Cryo-EM structure of the p300 catalytic core bound to the H4K12acK16ac nucleosome, class 1 (4.7 angstrom resolution)

Summary for 8HAI

• Entry DOI: 10.2210/pdb8hai/pdb
• EMDB information: 34591
• Descriptor: Histone H3.1, Histone H4, Histone H2A type 1-B/E, ... (6 entities in total)
• Functional Keywords: acetyl taransferase, complex, nucleosome, transferase, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 11
• Total formula weight: 312414.76

Authors

Kikuchi, M.,Morita, S.,Wakamori, M.,Shin, S.,Uchikubo-Kamo, T.,Shirouzu, M.,Umehara, T. (deposition date: 2022-10-26, release date: 2023-05-17, Last modification date: 2023-07-26)

• Primary citation: Kikuchi, M.,Morita, S.,Wakamori, M.,Sato, S.,Uchikubo-Kamo, T.,Suzuki, T.,Dohmae, N.,Shirouzu, M.,Umehara, T.; Epigenetic mechanisms to propagate histone acetylation by p300/CBP.; Nat Commun, 14:4103-4103, 2023; PubMed: 37460559; DOI: 10.1038/s41467-023-39735-4

Experimental method

ELECTRON MICROSCOPY (4.7 Å)