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4WDI
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BU of 4wdi by Molmil
Weak TCR binding to an unstable insulin epitope drives type 1 diabetes
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
著者Rizkallah, P.J, Cole, D.K.
登録日2014-09-08
公開日2015-06-24
最終更新日2015-07-01
実験手法X-RAY DIFFRACTION (2.313 Å)
主引用文献Distortion of the Major Histocompatibility Complex Class I Binding Groove to Accommodate an Insulin-derived 10-Mer Peptide.
J.Biol.Chem., 290, 2015
4WJ5
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BU of 4wj5 by Molmil
Structure of HLA-A2 in complex with an altered peptide ligands based on Mart-1 variant epitope
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Celie, P.H.N, Rodenko, B, Ovaa, H.
登録日2014-09-29
公開日2014-10-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Altered Peptide Ligands Revisited: Vaccine Design through Chemically Modified HLA-A2-Restricted T Cell Epitopes.
J Immunol., 193, 2014
4K7F
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BU of 4k7f by Molmil
Newly identified epitope V60 from HBV core protein complexed with HLA-A*0201
分子名称: Beta-2-microglobulin, Core protein, HLA class I histocompatibility antigen, ...
著者Meng, S.D, Zhang, Y, Wu, Y, Qi, J.X.
登録日2013-04-17
公開日2013-06-05
最終更新日2022-08-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The L60V variation in hepatitis B virus core protein elicits new epitope-specific cytotoxic T lymphocytes and enhances viral replication.
J.Virol., 87, 2013
4R42
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BU of 4r42 by Molmil
Crystal structure of KatB, a manganese catalase from Anabaena PCC7120
分子名称: Alr3090 protein, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
著者Bihani, S.C.
登録日2014-08-19
公開日2015-08-19
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.902 Å)
主引用文献KatB, a cyanobacterial Mn-catalase with unique active site configuration: Implications for enzyme function.
Free Radic. Biol. Med., 93, 2016
5L2J
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BU of 5l2j by Molmil
Crystal Structure of human CD1b in complex with C36-GMM
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-O-[(2R,3R)-3-hydroxy-2-tetradecyldocosanoyl]-alpha-L-idopyranose, ACETATE ION, ...
著者Gras, S, Shahine, A, Le Nours, J, Rossjohn, J.
登録日2016-08-02
公開日2016-11-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献T cell receptor recognition of CD1b presenting a mycobacterial glycolipid.
Nat Commun, 7, 2016
5L2K
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BU of 5l2k by Molmil
Crystal structure of GEM42 TCR-CD1b-GMM complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-O-[(2R,3R)-3-hydroxy-2-tetradecyldocosanoyl]-alpha-L-idopyranose, Beta-2-microglobulin, ...
著者Gras, S, Shahine, A, Le Nours, J, Rossjohn, J.
登録日2016-08-02
公開日2016-11-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献T cell receptor recognition of CD1b presenting a mycobacterial glycolipid.
Nat Commun, 7, 2016
7MLE
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BU of 7mle by Molmil
Crystal Structure of HLA-A*03:01 in complex with VVRPSVASK, an 9-mer epitope from Influenza B virus
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A alpha chain, ...
著者Gras, S, Nguyen, A.T, Szeto, C.
登録日2021-04-28
公開日2022-04-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Homologous peptides derived from influenza A, B and C viruses induce variable CD8 + T cell responses with cross-reactive potential.
Clin Transl Immunology, 11, 2022
1N76
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BU of 1n76 by Molmil
CRYSTAL STRUCTURE OF HUMAN SEMINAL LACTOFERRIN AT 3.4 A RESOLUTION
分子名称: CARBONATE ION, FE (III) ION, LACTOFERRIN, ...
著者Kumar, J, Weber, W, Munchau, S, Yadav, S, Singh, S.B, Sarvanan, K, Paramsivam, M, Sharma, S, Kaur, P, Bhushan, A, Srinivasan, A, Betzel, C, Singh, T.P.
登録日2002-11-12
公開日2003-02-18
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Crystal Structure of human seminal lactoferrin at 3.4A resolution
Indian J.Biochem.Biophys., 40, 2003
4U1J
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HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GAG protein, ...
著者Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
登録日2014-07-15
公開日2015-04-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
4U1N
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BU of 4u1n by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
登録日2014-07-15
公開日2015-04-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
4U1S
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BU of 4u1s by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
登録日2014-07-16
公開日2015-04-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
1I6Q
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BU of 1i6q by Molmil
Formation of a protein intermediate and its trapping by the simultaneous crystallization process: Crystal structure of an iron-saturated intermediate in the FE3+ binding pathway of camel lactoferrin at 2.7 resolution
分子名称: CARBONATE ION, FE (III) ION, LACTOFERRIN
著者Khan, J.A, Kumar, P, Srinivasan, A, Singh, T.P.
登録日2001-03-03
公開日2001-11-07
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Protein intermediate trapped by the simultaneous crystallization process. Crystal structure of an iron-saturated intermediate in the Fe3+ binding pathway of camel lactoferrin at 2.7 a resolution.
J.Biol.Chem., 276, 2001
4U1K
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BU of 4u1k by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
登録日2014-07-15
公開日2015-04-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
1SQY
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BU of 1sqy by Molmil
Structure of human diferric lactoferrin at 2.5A resolution using crystals grown at pH 6.5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ...
著者Vikram, P, Prem Kumar, R, Singh, N, Kumar, J, Ethayathulla, A.S, Sharma, S, Kaur, P, Singh, T.P.
登録日2004-03-22
公開日2004-04-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of human diferric lactoferrin at 2.5A resolution using crystals grown at pH 6.5.
To be Published
7KKZ
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BU of 7kkz by Molmil
Crystal structure of mouse anti-HIV potent neutralizing antibody M4H2K1
分子名称: 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Heavy chain of Fab fragment of mouse monoclonal antibody M4H2K1, ...
著者Kumar, S, Wilson, I.A.
登録日2020-10-28
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Neutralizing Antibodies Induced by First-Generation gp41-Stabilized HIV-1 Envelope Trimers and Nanoparticles.
Mbio, 12, 2021
7KMD
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BU of 7kmd by Molmil
Crystal structure of a HIV-1 clade C isolate Du172.17 HR1.R4.664 Env trimer in complex with human Fabs PGT124 and 35O22
分子名称: 124 Heavy chain, 124 Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kumar, S, Wilson, I.A.
登録日2020-11-02
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.39228582 Å)
主引用文献Neutralizing Antibodies Induced by First-Generation gp41-Stabilized HIV-1 Envelope Trimers and Nanoparticles.
Mbio, 12, 2021
7KLC
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BU of 7klc by Molmil
Crystal structure of M4H2K1 Fab bound to HIV-1 BG505 gp120 core and to 17b Fab
分子名称: 17b Fab heavy chain, 17b Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kumar, S, Wilson, I.A.
登録日2020-10-29
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Neutralizing Antibodies Induced by First-Generation gp41-Stabilized HIV-1 Envelope Trimers and Nanoparticles.
Mbio, 12, 2021
8SBK
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BU of 8sbk by Molmil
Structure of HLA-A*24:02 in complex with peptide, LYLPVRVLI (ATG2A).
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, LEU-TYR-LEU-PRO-VAL-ARG-VAL-LEU-ILE, ...
著者Mallik, L, Young, M.C, Sgourakis, N.G.
登録日2023-04-03
公開日2023-12-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion.
Sci Immunol, 8, 2023
8SBL
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BU of 8sbl by Molmil
Structure of HLA-A*24:02 in complex with peptide, LYLPVRVLI
分子名称: Beta-2-microglobulin, LEU-TYR-LEU-PRO-VAL-ARG-VAL-LEU-ILE, MHC class I antigen
著者Mallik, L, Young, M.C, Sgourakis, N.G.
登録日2023-04-03
公開日2023-12-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion.
Sci Immunol, 8, 2023
8SOS
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BU of 8sos by Molmil
Human CD1d presenting sphingomyelin C24:1 in complex with VHH nanobody 1D17
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, Beta-2-microglobulin, ...
著者Shahine, A, Rossjohn, J.
登録日2023-04-29
公開日2023-12-13
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Enhanced CD1d phosphatidylserine presentation using a single-domain antibody promotes immunomodulatory CD1d-TIM-3 interactions.
J Immunother Cancer, 11, 2023
8SGM
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BU of 8sgm by Molmil
Crystal Structure of CD1d-lipid complexed with Beta-2-Microglobulin, TCR Alpha-Chain and TCR Beta-Chain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, ...
著者Chan Yew Poa, K.T.O, Le Nours, J, Rossjohn, J.
登録日2023-04-12
公開日2024-04-24
実験手法X-RAY DIFFRACTION (2.50000215 Å)
主引用文献Semi-invariant human type II Natural Killer T cells recognise CD1d independently of bound lipids.
To Be Published
8SGB
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BU of 8sgb by Molmil
Crystal Structure of CD1d-lipid complexed with Beta-2-Microglobulin, TCR Alpha-Chain and TCR Beta-Chain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, Beta-2-microglobulin, ...
著者Chan Yew Poa, K.T.O, Le Nours, J, Rossjohn, J.
登録日2023-04-12
公開日2024-04-24
実験手法X-RAY DIFFRACTION (2.80001545 Å)
主引用文献Semi-invariant human type II Natural Killer T cells recognise CD1d independently of bound lipids.
To Be Published
1L5T
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BU of 1l5t by Molmil
Crystal Structure of a Domain-Opened Mutant (R121D) of the Human Lactoferrin N-lobe Refined From a Merohedrally-Twinned Crystal Form.
分子名称: lactoferrin
著者Jameson, G.B, Anderson, B.F, Breyer, W.A, Tweedie, J.W, Baker, E.N.
登録日2002-03-07
公開日2002-03-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of a domain-opened mutant (R121D) of the human lactoferrin N-lobe refined from a merohedrally twinned crystal form.
Acta Crystallogr.,Sect.D, 58, 2002
6D78
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BU of 6d78 by Molmil
The complex between high-affinity TCR DMF5(alpha-D26Y,beta-L98W) and human Class I MHC HLA-A2 with the bound MART-1(27-35)peptide
分子名称: Beta-2-microglobulin, DMF5 alpha chain,DMF5 alpha chain, DMF5 beta chain,DMF5 beta chain, ...
著者Hellman, L.M, Singh, N.K.
登録日2018-04-24
公開日2019-04-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.347 Å)
主引用文献Improving T Cell Receptor On-Target Specificity via Structure-Guided Design.
Mol. Ther., 27, 2019
6DKP
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BU of 6dkp by Molmil
The complex among DMF5(alpha-D26Y, alpha-Y50A,beta-L98W) TCR, human Class I MHC HLA-A2 and MART-1(26-35)(A27L) peptide
分子名称: Beta-2-microglobulin, DMF5 T-cell Receptor Alpha Chain fusion, DMF5 T-cell Receptor Beta Chain fusion, ...
著者Hellman, L.M, Singh, N.K.
登録日2018-05-30
公開日2019-04-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.966 Å)
主引用文献Improving T Cell Receptor On-Target Specificity via Structure-Guided Design.
Mol. Ther., 27, 2019

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件を2024-08-14に公開中

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