4K7F

Newly identified epitope V60 from HBV core protein complexed with HLA-A*0201

Summary for 4K7F
DescriptorHLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Core protein, ... (4 entities in total)
Functional Keywordshost-virus interaction, immune response, disease mutation, viral replication, ig-like domain, immune system, tcr, membrane glycoprotein, viral capsid protein
Biological sourceHomo sapiens (human)
More
Cellular locationMembrane; Single-pass type I membrane protein: P01892
Secreted: P61769
Total number of polymer chains6
Total formula weight89595.67
Authors
Meng, S.D.,Zhang, Y.,Wu, Y.,Qi, J.X. (deposition date: 2013-04-17, release date: 2013-06-05)
Primary citationGao, G.F.,Li, X.,Liu, J.,Meng, S.D.,Qiu, L.,Ren, Y.,Wu, Y.,Xu, D.,Zhang, Y.,Zhao, B.
The L60V variation in HBV core protein elicits new epitope-specific cytotoxic T lymphocytes and enhances viral replication
J.Virol., 2013
PubMed: 23678186
DOI: 110.1128/JVI.00577-13
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation
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PDB entries from 2021-06-16