PDB: 30476 件ウェブページステータス検索Chemie searchBIRD

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5KDR	The crystal structure of carboxyltransferase from Staphylococcus Aureus bound to the antimicrobial agent moiramide B. 分子名称: 1,2-ETHANEDIOL, Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ... 著者 Silvers, M.A, Pakhomova, S, Neau, D, Silvers, W.C, Anzalone, N, Taylor, C.M, Waldrop, G.L. 登録日 2016-06-08 公開日 2016-08-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structure of Carboxyltransferase from Staphylococcus aureus Bound to the Antibacterial Agent Moiramide B. Biochemistry, 55, 2016
8GJF	afupcna bound with peptide mimetic 分子名称: LYS-ARG-ARG-GLN-THR-SER-MET-THR-ASP-PHE-TYR-HIS-SER-LYS-ARG, Proliferating cell nuclear antigen 著者 Vandborg, B, Bruning, J.B. 登録日 2023-03-15 公開日 2024-01-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Towards a High-Affinity Peptidomimetic Targeting Proliferating Cell Nuclear Antigen from Aspergillus fumigatus. J Fungi, 9, 2023
5KF7	Structure of proline utilization A from Sinorhizobium meliloti complexed with L-tetrahydrofuroic acid and NAD+ in space group P3121 分子名称: Bifunctional protein PutA, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, ... 著者 Tanner, J.J. 登録日 2016-06-12 公開日 2016-10-05 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structures of Proline Utilization A (PutA) Reveal the Fold and Functions of the Aldehyde Dehydrogenase Superfamily Domain of Unknown Function. J.Biol.Chem., 291, 2016
8GJC	X-ray crystallographic structure of a beta-hairpin peptide derived from Abeta 17-35. (ORN)LVFFAED(ORN)GAI(N-Me-Ile)GLM 分子名称: DI(HYDROXYETHYL)ETHER, METHIONINE, beta-hairpin peptide derived from Abeta 17-35, ... 著者 Kreutzer, A.G, Ruttenberg, S.M, Nowick, J.S. 登録日 2023-03-15 公開日 2024-01-17 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.431 Å) 主引用文献 beta-Hairpin Alignment Alters Oligomer Formation in A beta-Derived Peptides. Biochemistry, 63, 2024
5JZL	The Structure of Monomeric Ultra Stable Green Fluorescent Protein 分子名称: CHLORIDE ION, Green fluorescent protein, SODIUM ION 著者 Gunn, N.J, Yong, K.J, Scott, D.J, Griffin, M.D.W. 登録日 2016-05-17 公開日 2017-12-06 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A Novel Ultra-Stable, Monomeric Green Fluorescent Protein For Direct Volumetric Imaging of Whole Organs Using CLARITY. Sci Rep, 8, 2018
7WUW	Crystal structure of AziU3/U2 from Streptomyces sahachiroi 分子名称: AziU2, AziU3, MAGNESIUM ION, ... 著者 Kurosawa, S, Yoshida, A, Tomita, T, Nishiyama, M. 登録日 2022-02-09 公開日 2022-09-07 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Molecular Basis for Enzymatic Aziridine Formation via Sulfate Elimination. J.Am.Chem.Soc., 144, 2022
8GJD	X-ray crystallographic structure of a beta-hairpin peptide derived from Abeta 17-36. (ORN)LVFFAED(ORN)AII(N-Me-Gly)LMV 分子名称: Beta-hairpin peptide derived from Abeta 17-36, IODIDE ION 著者 Kreutzer, A.G, Ruttenberg, S.M, Nowick, J.S, Truex, N.L. 登録日 2023-03-15 公開日 2024-01-17 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 beta-Hairpin Alignment Alters Oligomer Formation in A beta-Derived Peptides. Biochemistry, 63, 2024
8GDU	Crystal structure of a mutant methyl transferase from Methanosarcina acetivorans, Northeast Structural Genomics Consortium (NESG) Target MvR53-11M 分子名称: Methyltransferase domain-containing protein, S-ADENOSYL-L-HOMOCYSTEINE 著者 Forouhar, F, Banayan, N.E, Loughlin, B.L, Singh, S, Wong, V, Hunt, H.S, Handelman, S.K, Price, N, Hunt, J.F. 登録日 2023-03-06 公開日 2024-01-24 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Systematic enhancement of protein crystallization efficiency by bulk lysine-to-arginine (KR) substitution. Protein Sci., 33, 2024
7XNE	Crystal structure of CBP bromodomain liganded with Y08284 分子名称: CREB-binding protein, GLYCEROL, N-[3-(1-cyclopropylpyrazol-4-yl)-2-fluoranyl-5-[(1S)-1-oxidanylethyl]phenyl]-3-ethanoyl-7-methoxy-indolizine-1-carboxamide 著者 Xiang, Q, Wang, C, Wu, T, Zhang, C, Hu, Q, Luo, G, Hu, J, Zhuang, X, Zou, L, Shen, H, Wu, X, Zhang, Y, Kong, X, Xu, Y. 登録日 2022-04-28 公開日 2022-07-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Design, Synthesis, and Biological Evaluation of 1-(Indolizin-3-yl)ethan-1-ones as CBP Bromodomain Inhibitors for the Treatment of Prostate Cancer. J.Med.Chem., 65, 2022
5K3I	Crystal structure of Acyl-CoA oxidase-1 in Caenorhabditis elegans complexed with FAD and ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Acyl-coenzyme A oxidase, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Zhang, X, Li, K, Jones, R.A, Bruner, S.D, Butcher, R.A. 登録日 2016-05-19 公開日 2016-08-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.683 Å) 主引用文献 Structural characterization of acyl-CoA oxidases reveals a direct link between pheromone biosynthesis and metabolic state in Caenorhabditis elegans. Proc.Natl.Acad.Sci.USA, 113, 2016
8GC7	Bruton's tyrosine kinase in complex with 5-(piperidin-1-yl)-3-{[4-(piperidin-4-yl)phenyl]amino}pyrazine-2-carboxamide 分子名称: 1,2-ETHANEDIOL, 5-(piperidin-1-yl)-3-[4-(piperidin-4-yl)anilino]pyrazine-2-carboxamide, CHLORIDE ION, ... 著者 Gajewski, S. 登録日 2023-03-01 公開日 2024-01-31 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Kinase-impaired BTK mutations are susceptible to clinical-stage BTK and IKZF1/3 degrader NX-2127. Science, 383, 2024
7X0E	Structure of Pseudomonas NRPS protein, AmbB-TC in apo form 分子名称: AMB antimetabolite synthase AmbB, N-methyl-N-[(2S,3R,4R,5R)-2,3,4,5,6-pentakis(oxidanyl)hexyl]nonanamide 著者 ChuYuanKee, M, Bharath, S.R, Song, H. 登録日 2022-02-22 公開日 2022-07-06 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural insights into the substrate-bound condensation domains of non-ribosomal peptide synthetase AmbB. Sci Rep, 12, 2022
8GLY	Crystal structure of T252E-CYP199A4 in complex with 4-hydroxybenzoic acid 分子名称: CHLORIDE ION, Cytochrome P450, P-HYDROXYBENZOIC ACID, ... 著者 Lee, J.H.Z, Bruning, J.B, Bell, S.G. 登録日 2023-03-23 公開日 2024-02-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 An In Crystallo Reaction with an Engineered Cytochrome P450 Peroxygenase. Chemistry, 30, 2024
8G48	FphE, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E, dimeric apo form 分子名称: Fluorophosphonate-binding serine hydrolase E 著者 Fellner, M. 登録日 2023-02-08 公開日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 FphE, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E, dimeric apo form To Be Published
8GEQ	E. eligens beta-glucuronidase bound to ceritinib-glucuronide 分子名称: 4-amino-5-chloro-2-{4-(1-beta-D-glucopyranuronosylpiperidin-4-yl)-5-methyl-2-[(propan-2-yl)oxy]anilino}pyrimidine, Beta-glucuronidase 著者 Simpson, J.B, Kowalewski, M.K, Redinbo, M.R. 登録日 2023-03-07 公開日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Diverse Human Therapeutics Impact Hormone and Neurotransmitter Homeostasis by Inhibiting Gut Microbial Enzymes To Be Published
5K4C	Structure of eukaryotic translation initiation factor 3 subunit D (eIF3d) cap binding domain from Nasonia vitripennis, Crystal form 2 分子名称: Eukaryotic translation initiation factor 3 subunit D, GLYCEROL 著者 Kranzusch, P.J, Lee, A.S.Y, Doudna, J.A, Cate, J.H.D. 登録日 2016-05-20 公開日 2016-07-27 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.698 Å) 主引用文献 eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation. Nature, 536, 2016
5K6R	Crystal structure of Arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylamino-carbonyl-triazolinone herbicide, thiencarbazone-methyl 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-4-METHYL-2-OXO-2,3-DIHYDRO-1,3-THIAZOL-5-YL}ETHYL TRIHYDROGEN DIPHOSPHATE, Acetolactate synthase, ... 著者 Garcia, M.D, Lonhienne, T, Guddat, L.W. 登録日 2016-05-25 公開日 2017-02-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.734 Å) 主引用文献 Comprehensive understanding of acetohydroxyacid synthase inhibition by different herbicide families. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5K4M	Directed evolutionary changes in MBL super family - NDM-1 Round 10 crystal-3 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, Metallo-beta-lactamase type 2, ... 著者 Hong, N.-S, Jackson, C.J, Carr, P.D. 登録日 2016-05-20 公開日 2017-04-26 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Enzyme evolvability is contingent on the initial sequence background To Be Published
8GM1	Crystal structure of T252E-CYP199A4 in complex with 4-methoxybenzoic acid soaked with 1 mM hydrogen peroxide 分子名称: 4-METHOXYBENZOIC ACID, CHLORIDE ION, Cytochrome P450, ... 著者 Lee, J.H.Z, Bruning, J.B, Bell, S.G. 登録日 2023-03-24 公開日 2024-02-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 An In Crystallo Reaction with an Engineered Cytochrome P450 Peroxygenase. Chemistry, 30, 2024
8G49	FphE, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E, Oxadiazolone compound 3 bound 分子名称: Fluorophosphonate-binding serine hydrolase E, methyl 2-formyl-2-[3-methyl-4-(3-phenoxybenzamido)phenyl]hydrazine-1-carboxylate 著者 Fellner, M, Bakker, A.T, Martin, N.I, Stelt, M. 登録日 2023-02-08 公開日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 FphE, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E, Oxadiazolone compound 3 bound To be published
5K7B	Beclin 2 CCD homodimer 分子名称: Beclin-2 著者 Su, M, Sinha, S. 登録日 2016-05-25 公開日 2017-03-08 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 BECN2 interacts with ATG14 through a metastable coiled-coil to mediate autophagy. Protein Sci., 26, 2017
8G8J	Crystal structure of human DNA polymerase eta incorporating ITP across dT 分子名称: CALCIUM ION, DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3'), DNA (5'-D(P*AP*TP*TP*CP*TP*CP*AP*CP*AP*CP*T)-3'), ... 著者 Jung, H. 登録日 2023-02-17 公開日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Crystal structure of human DNA polymerase eta incorporating ITP across dT To Be Published
8G8R	RelB NLS in complex with Importin alpha 2 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Importin subunit alpha-1, Transcription factor RelB 著者 Tsimbslyuk, S, Stewart, M, Forwood, J.K. 登録日 2023-02-19 公開日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 monopartite p52 NLS in complex with Importin alpha 2 To Be Published
8G8Q	RelB NLS in complex with Importin alpha 2 分子名称: Importin subunit alpha-1, bacterial peptide, monopartite p52 NLS 著者 Tsimbslyuk, S, Stewart, M, Forwood, J.K. 登録日 2023-02-19 公開日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 p52 monopartite NLS in complex with Importin alpha 2 To Be Published
7X6K	SARS-CoV-2 3CL protease (3CLpro) in complex with compound 3w 分子名称: 1H-indole-2-carbaldehyde, 3C-like proteinase 著者 Su, H, Nie, T, Xie, H, Li, Z.W, Li, M.J, Xu, Y. 登録日 2022-03-07 公開日 2022-07-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Small-Molecule Thioesters as SARS-CoV-2 Main Protease Inhibitors: Enzyme Inhibition, Structure-Activity Relationships, Antiviral Activity, and X-ray Structure Determination. J.Med.Chem., 65, 2022

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