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PDB: 65 results

8G49
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FphE, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E, Oxadiazolone compound 3 bound
Descriptor: Fluorophosphonate-binding serine hydrolase E, methyl 2-formyl-2-[3-methyl-4-(3-phenoxybenzamido)phenyl]hydrazine-1-carboxylate
Authors:Fellner, M, Bakker, A.T, Martin, N.I, Stelt, M.
Deposit date:2023-02-08
Release date:2024-02-21
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:FphE, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E, Oxadiazolone compound 3 bound
To be published
8T88
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FphE, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E, Oxadiazolone JJ004 bound
Descriptor: Fluorophosphonate-binding serine hydrolase E, MAGNESIUM ION, methyl 2-formyl-2-[4-(undec-10-ynamido)phenyl]hydrazine-1-carboxylate
Authors:Fellner, M.
Deposit date:2023-06-22
Release date:2024-03-06
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Development of Oxadiazolone Activity-Based Probes Targeting FphE for Specific Detection of Staphylococcus aureus Infections.
J.Am.Chem.Soc., 146, 2024
8T87
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FphE, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E, unbound dimer crystal form 1
Descriptor: Fluorophosphonate-binding serine hydrolase E, MAGNESIUM ION
Authors:Fellner, M.
Deposit date:2023-06-22
Release date:2024-03-06
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Development of Oxadiazolone Activity-Based Probes Targeting FphE for Specific Detection of Staphylococcus aureus Infections.
J.Am.Chem.Soc., 146, 2024
8FTP
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FphH, Staphylococcus aureus fluorophosphonate-binding serine hydrolases H, apo form
Descriptor: Alpha/beta fold hydrolase, CALCIUM ION
Authors:Fellner, M.
Deposit date:2023-01-12
Release date:2023-10-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Biochemical and Cellular Characterization of the Function of Fluorophosphonate-Binding Hydrolase H (FphH) in Staphylococcus aureus Support a Role in Bacterial Stress Response.
Acs Infect Dis., 9, 2023
8G0N
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FphI, Staphylococcus aureus fluorophosphonate-binding serine hydrolases I, apo form
Descriptor: CHLORIDE ION, Fluorophosphonate-binding serine hydrolase I, MAGNESIUM ION
Authors:Fellner, M.
Deposit date:2023-01-31
Release date:2024-02-14
Method:X-RAY DIFFRACTION (1.14 Å)
Cite:FphI, Staphylococcus aureus fluorophosphonate-binding serine hydrolases I, apo form
To Be Published
8G48
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FphE, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E, dimeric apo form
Descriptor: Fluorophosphonate-binding serine hydrolase E
Authors:Fellner, M.
Deposit date:2023-02-08
Release date:2024-02-21
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:FphE, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E, dimeric apo form
To Be Published
8SBQ
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FphE, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E, fluorophosphonate JB101 bound
Descriptor: Fluorophosphonate-binding serine hydrolases E, MAGNESIUM ION, ethyl (R)-(10-{[(but-3-yn-1-yl)carbamoyl]oxy}decyl)phosphonofluoridate
Authors:Fellner, M.
Deposit date:2023-04-04
Release date:2024-04-17
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:FphE, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E, fluorophosphonate JB101 bound
To Be Published
8S9J
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FphA, Staphylococcus aureus fluorophosphonate-binding serine hydrolases A, apo form
Descriptor: Fluorophosphonate-binding serine hydrolase A, SULFATE ION
Authors:Fellner, M.
Deposit date:2023-03-28
Release date:2024-04-10
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:FphA, Staphylococcus aureus fluorophosphonate-binding serine hydrolases A, apo form
To Be Published
8S9R
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SAL2, Staphylococcus aureus lipase 2 (geh, lip2), apo form
Descriptor: CALCIUM ION, Lipase 2, PHOSPHATE ION, ...
Authors:Fellner, M.
Deposit date:2023-03-30
Release date:2024-04-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:SAL2, Staphylococcus aureus lipase 2 (geh, lip2), apo form
To Be Published
6OC5
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Lanthanide-dependent methanol dehydrogenase XoxF from Methylobacterium extorquens, in complex with Lanthanum
Descriptor: LANTHANUM (III) ION, Lanthanide-dependent methanol dehydrogenase XoxF
Authors:Fellner, M, Good, N.M, Martinez-Gomez, N.C, Hausinger, R.P, Hu, J.
Deposit date:2019-03-21
Release date:2020-05-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Lanthanide-dependent alcohol dehydrogenases require an essential aspartate residue for metal coordination and enzymatic function.
J.Biol.Chem., 295, 2020
6OC6
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Lanthanide-dependent methanol dehydrogenase XoxF from Methylobacterium extorquens, in complex with Lanthanum and Pyrroloquinoline quinone
Descriptor: LANTHANUM (III) ION, Lanthanide-dependent methanol dehydrogenase XoxF, PYRROLOQUINOLINE QUINONE
Authors:Fellner, M, Good, N.M, Martinez-Gomez, N.C, Hausinger, R.P, Hu, J.
Deposit date:2019-03-21
Release date:2020-05-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Lanthanide-dependent alcohol dehydrogenases require an essential aspartate residue for metal coordination and enzymatic function.
J.Biol.Chem., 295, 2020
6D6Z
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Structure of the malate racemase apoprotein from Thermoanaerobacterium thermosaccharolyticum
Descriptor: Malate racemase Mar2
Authors:Fellner, M, Hausinger, R.P, Hu, J.
Deposit date:2018-04-23
Release date:2019-04-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Uncovering a superfamily of nickel-dependent hydroxyacid racemases and epimerases.
Sci Rep, 10, 2020
4TLF
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Crystal structure of Thiol dioxygenase from Pseudomonas aeruginosa
Descriptor: 3-mercaptopropionate dioxygenase, FE (II) ION
Authors:Fellner, M, Tchesnokov, E.P, Jameson, G.N.L, Wilbanks, S.M.
Deposit date:2014-05-29
Release date:2015-06-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.137 Å)
Cite:The Cysteine Dioxygenase Homologue from Pseudomonas aeruginosa Is a 3-Mercaptopropionate Dioxygenase.
J.Biol.Chem., 290, 2015
4UBG
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Resting state of rat cysteine dioxygenase C93G variant
Descriptor: Cysteine dioxygenase type 1, FE (II) ION, SODIUM ION
Authors:Fellner, M, Tchesnokov, E.P, Jameson, G.N, Wilbanks, S.M.
Deposit date:2014-08-13
Release date:2014-11-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Cys-Tyr Cross-Link of Cysteine Dioxygenase Changes the Optimal pH of the Reaction without a Structural Change.
Biochemistry, 53, 2014
4Z82
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Cysteine bound rat cysteine dioxygenase C164S variant at pH 8.1
Descriptor: CYSTEINE, Cysteine dioxygenase type 1, FE (II) ION
Authors:Fellner, M, Tchesnokov, E.P, Siakkou, E, Rutledge, M.T, Kanitz, M, Jameson, G.N.L, Wilbanks, S.M.
Deposit date:2015-04-08
Release date:2016-06-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Influence of cysteine 164 on active site structure in rat cysteine dioxygenase.
J.Biol.Inorg.Chem., 21, 2016
6VH9
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FphF, Staphylococcus aureus fluorophosphonate-binding serine hydrolases F, apo form
Descriptor: Esterase family protein, SODIUM ION
Authors:Fellner, M, Jamieson, S.A, Brewster, J.L, Mace, P.D.
Deposit date:2020-01-09
Release date:2020-09-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Structural Basis for the Inhibitor and Substrate Specificity of the Unique Fph Serine Hydrolases of Staphylococcus aureus .
Acs Infect Dis., 6, 2020
6VHD
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FphF, Staphylococcus aureus fluorophosphonate-binding serine hydrolases F, KT129 bound
Descriptor: (2~{R})-2-phenylpiperidine-1-carbaldehyde, Esterase family protein
Authors:Fellner, M, Mace, P.D.
Deposit date:2020-01-09
Release date:2020-09-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural Basis for the Inhibitor and Substrate Specificity of the Unique Fph Serine Hydrolases of Staphylococcus aureus .
Acs Infect Dis., 6, 2020
6VHE
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FphF, Staphylococcus aureus fluorophosphonate-binding serine hydrolases F, KT130 bound
Descriptor: (2~{R})-2-phenylpiperidine-1-carbaldehyde, Esterase family protein
Authors:Fellner, M, Mace, P.D.
Deposit date:2020-01-09
Release date:2020-09-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structural Basis for the Inhibitor and Substrate Specificity of the Unique Fph Serine Hydrolases of Staphylococcus aureus .
Acs Infect Dis., 6, 2020
6WCX
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FphF, Staphylococcus aureus fluorophosphonate-binding serine hydrolases F, substrate bound
Descriptor: Esterase family protein, HEPTAN-1-OL
Authors:Fellner, M, Mace, P.D.
Deposit date:2020-03-31
Release date:2020-09-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Structural Basis for the Inhibitor and Substrate Specificity of the Unique Fph Serine Hydrolases of Staphylococcus aureus .
Acs Infect Dis., 6, 2020
6DG3
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LarE, a sulfur transferase involved in synthesis of the cofactor for lactate racemase, in complex with caesium
Descriptor: CESIUM ION, PHOSPHATE ION, Pyridinium-3,5-biscarboxylic acid mononucleotide sulfurtransferase
Authors:Fellner, M, Hausinger, R.P, Hu, J.
Deposit date:2018-05-16
Release date:2019-05-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.944 Å)
Cite:Unique cesium-binding sites in proteins, a case study with the sacrificial sulfur transferase LarE
J Life Sci, 2021
6ECJ
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BU of 6ecj by Molmil
Human cytochrome c G41T
Descriptor: Cytochrome c, HEME C
Authors:Fellner, M, Jameson, G.N.L, Ledgerwood, E.C, Wilbanks, S.M.
Deposit date:2018-08-08
Release date:2019-08-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Altered structure and dynamics of pathogenic cytochrome c variants correlate with increased apoptotic activity.
Biochem.J., 2021
4WVZ
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Crystal structure of artificial crosslinked thiol dioxygenase G95C variant from Pseudomonas aeruginosa
Descriptor: 3-mercaptopropionate dioxygenase, FE (II) ION
Authors:Fellner, M, Tchesnokov, E.P, Jameson, G.N.L, Wilbanks, S.M.
Deposit date:2014-11-09
Release date:2016-02-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Substrate and pH-Dependent Kinetic Profile of 3-Mercaptopropionate Dioxygenase from Pseudomonas aeruginosa.
Biochemistry, 55, 2016
4YNI
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Iron free succinate bound rat cysteine dioxygenase
Descriptor: Cysteine dioxygenase type 1, SODIUM ION, SUCCINIC ACID
Authors:Fellner, M, Tchesnokov, E.P, Jameson, G.N.L, Wilbanks, S.M.
Deposit date:2015-03-10
Release date:2016-03-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.404 Å)
Cite:Iron free succinate bound rat cysteine dioxygenase
To be published
4YSF
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Resting state of rat cysteine dioxygenase H155N variant
Descriptor: Cysteine dioxygenase type 1, FE (II) ION
Authors:Fellner, M, Tchesnokov, E.P, Jameson, G.N.L, Wilbanks, S.M.
Deposit date:2015-03-17
Release date:2016-07-20
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Resting state of rat cysteine dioxygenase H155N variant
To be published
4YYO
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Resting state of rat cysteine dioxygenase C164S variant
Descriptor: CHLORIDE ION, Cysteine dioxygenase type 1, FE (II) ION
Authors:Fellner, M, Tchesnokov, E.P, Siakkou, E, Rutledge, M.T, Jameson, G.N.L, Wilbanks, S.M.
Deposit date:2015-03-24
Release date:2016-06-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Influence of cysteine 164 on active site structure in rat cysteine dioxygenase.
J.Biol.Inorg.Chem., 21, 2016

 

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