8GEQ

E. eligens beta-glucuronidase bound to ceritinib-glucuronide

Summary for 8GEQ

• Entry DOI: 10.2210/pdb8geq/pdb
• Descriptor: Beta-glucuronidase, 4-amino-5-chloro-2-{4-(1-beta-D-glucopyranuronosylpiperidin-4-yl)-5-methyl-2-[(propan-2-yl)oxy]anilino}pyrimidine (3 entities in total)
• Functional Keywords: beta-glucuronidase, inhibitor, glucuronide, hydrolase
• Biological source: Lachnospira eligens
• Total number of polymer chains: 1
• Total formula weight: 70387.14

Authors

Simpson, J.B.,Kowalewski, M.K.,Redinbo, M.R. (deposition date: 2023-03-07, release date: 2024-02-14)

• Primary citation: Simpson, J.B.,Redinbo, M.R.; Diverse Human Therapeutics Impact Hormone and Neurotransmitter Homeostasis by Inhibiting Gut Microbial Enzymes; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.75 Å)